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Philip L. De Jager

Philip L. De Jager

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Genetics
USA
2025
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Genetics and Molecular Biology
USA
2024

D-Index & Metrics

Genetics

D-Index
138
Citations
100210
World Ranking
195
National Ranking
103

Medicine

D-Index
146
Citations
110298
World Ranking
1317
National Ranking
760

Research.com Recognitions

  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award

Overview

Philip L. De Jager is affiliated with Columbia University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on subfields such as Molecular Biology, Physiology, Neurology, Genetics, and Psychiatry and Mental Health.

The scientific work conducted involves multiple key topics, including:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Bioinformatics and Genomic Networks
  • Genetic Associations and Epidemiology
  • Dementia and Cognitive Impairment Research
  • Epigenetics and DNA Methylation
  • Multiple Sclerosis Research Studies

Notable recent papers authored by Philip L. De Jager or included in their body of work are:

  • Microglia states and nomenclature: A field at its crossroads, 2022, Neuron
  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation, 2020, Nature Medicine
  • Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease, 2020, Nature Communications
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level, 2022, Nature Neuroscience
  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications

Their frequent coauthors reflect collaboration across diverse expertise and include:

  • David A. Bennett
  • Vilas Menon
  • Julie A. Schneider
  • Nicholas T. Seyfried
  • Hans-Ulrich Klein

Philip L. De Jager's work often appears in the following publication venues, demonstrating continued contributions to both preprint and peer-reviewed literature:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s & Dementia
  • Nature Communications
  • Neurology
  • SSRN Electronic Journal

Best Publications

  • Integrative analysis of 111 reference human epigenomes

    Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors.

    Alexandra Chloé Villani;Alexandra Chloé Villani;Rahul Satija;Rahul Satija;Gary Reynolds;Siranush Sarkizova

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Risk alleles for multiple sclerosis identified by a genomewide study.

    David A. Hafler;Alastair Compston;Stephen Sawcer;Mark J. Daly

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants

    Kyle Kai How Farh;Alexander Marson;Jiang Zhu;Markus Kleinewietfeld

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    Eli A Stahl;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Gang Xie

  • Charting a dynamic DNA methylation landscape of the human genome

    Michael J. Ziller;Hongcang Gu;Fabian Müller;Julie Donaghey;Julie Donaghey

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Alterations of the human gut microbiome in multiple sclerosis

    Sushrut Jangi;Roopali Gandhi;Laura M. Cox;Ning Li

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M L Baselmans;Jan-Emmanuel De Neve;Patrick Turley

  • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

    Cornelius A. Rietveld;Sarah E. Medland;Jaime Lane Derringer;Jian Yang

  • Parkinson's Disease: Genetics and Pathogenesis

    Joshua M. Shulman;Philip L. De Jager;Mel B. Feany

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

Frequent Co-Authors

David A. Bennett
David A. Bennett Rush University Medical Center
Lori B. Chibnik
Lori B. Chibnik Harvard University
David A. Hafler
David A. Hafler Yale University
Lei Yu
Lei Yu Rush University Medical Center
Julie A. Schneider
Julie A. Schneider Rush University Medical Center
Towfique Raj
Towfique Raj Icahn School of Medicine at Mount Sinai
Joshua M. Shulman
Joshua M. Shulman Baylor College of Medicine
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor
Denis A. Evans
Denis A. Evans Rush University Medical Center

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