World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Genetics
USA
2026

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Best Scientists

D-Index
189
Citations
167262
World Ranking
439
National Ranking
292

Genetics

D-Index
186
Citations
167155
World Ranking
40
National Ranking
24

Medicine

D-Index
194
Citations
179593
World Ranking
222
National Ranking
149

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Hakon Hakonarson is affiliated with the Children's Hospital of Philadelphia in the United States. Their research spans extensive work in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a specialization in multiple subfields including Genetics, Molecular Biology, Immunology, Surgery, and Epidemiology.

The scientist's publications cover a variety of main research topics:

  • Genetic Associations and Epidemiology
  • Genomics and Rare Diseases
  • Genetics and Neurodevelopmental Disorders
  • Genomic variations and chromosomal abnormalities
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Asthma and respiratory diseases

Their prolific publication record includes significant recent papers:

  • "Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study" (2020), published in Nature Communications
  • "Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients" (2020), published in European Respiratory Journal
  • "Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease" (2020), published in Nature Genetics
  • "A cross-disorder dosage sensitivity map of the human genome" (2022), published in Cell
  • "Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel" (2020), published in JAMA Neurology

Frequently appearing publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine
  • Nature Communications
  • American Journal of Medical Genetics Part A
  • UNC Libraries

Collaborations feature prominently in Hakonarson's research. Their most frequent co-authors are:

  • Hui-Qi Qu
  • Joseph Glessner
  • Frank Mentch
  • Patrick Sleiman
  • Yichuan Liu

Among professional recognitions, Hakonarson is a Member of the Association of American Physicians.

Best Publications

  • ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

    Kai Wang;Mingyao Li;Hakon Hakonarson

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Functional impact of global rare copy number variation in autism spectrum disorders

    Dalila Pinto;Alistair T. Pagnamenta;Lambertus Klei;Richard Anney

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • An Improved Framework for Confound Regression and Filtering for Control of Motion Artifact in the Preprocessing of Resting-State Functional Connectivity Data

    Theodore D. Satterthwaite;Mark A. Elliott;Raphael T. Gerraty;Kosha Ruparel

  • PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

    Kai Wang;Mingyao Li;Dexter Hadley;Rui Liu

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

    Joseph T. Glessner;Kai Wang;Guiqing Cai;Olena Korvatska

  • Identification of ALK as a major familial neuroblastoma predisposition gene

    Yaël P. Mossé;Marci Laudenslager;Luca Longo;Kristina A. Cole

  • Sex differences in the structural connectome of the human brain.

    Madhura Ingalhalikar;Alex Smith;Drew Parker;Theodore D. Satterthwaite

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

    Sekar Kathiresan;Benjamin F Voight;Shaun Purcell;Kiran Musunuru

  • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

    Anna Helgadottir;Andrei Manolescu;Gudmar Thorleifsson;Solveig Gretarsdottir

Frequent Co-Authors

Struan F.A. Grant
Struan F.A. Grant University of Pennsylvania
Patrick M.A. Sleiman
Patrick M.A. Sleiman Children's Hospital of Philadelphia
Jonathan P. Bradfield
Jonathan P. Bradfield Children's Hospital of Philadelphia
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia
Brendan J. Keating
Brendan J. Keating University of Pennsylvania
Rosetta M. Chiavacci
Rosetta M. Chiavacci Children's Hospital of Philadelphia
Mingyao Li
Mingyao Li University of Pennsylvania
Gail P. Jarvik
Gail P. Jarvik University of Washington
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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