World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
100
Citations
45076
World Ranking
747
National Ranking
372

Medicine

D-Index
103
Citations
46718
World Ranking
7264
National Ranking
3805

Overview

Struan F.A. Grant is affiliated with the University of Pennsylvania in the United States and has an extensive publication record spanning fields related to biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on genetic associations and epidemiology, epigenetics and DNA methylation, RNA modifications and cancer, genomics and chromatin dynamics, birth, development, and health, immune cell function and interaction, and pancreatic function and diabetes.

The scientist's publication venues highlight a broad engagement with both foundational and clinical research journals. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • SLEEP
  • Diabetes
  • Nature Communications

Grant's work includes notable papers published recently, such as:

  • Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program (2024, Science)
  • A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation (2022, Nature Genetics)
  • Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes (2020, Diabetes)
  • Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual (2021, Genome Biology)
  • Genetic Determinants of Childhood Obesity (2020, Molecular Diagnosis & Therapy)

The scientist collaborates frequently with several researchers, with co-authorship counts indicating sustained partnerships. Their most common collaborators include:

  • Andrew D. Wells
  • Alessandra Chesi
  • James A. Pippin
  • Matthew C. Pahl
  • Babette S. Zemel

Struan F.A. Grant's subfields of study reflect a concentration in areas underpinning molecular mechanisms and clinical applications. These subfields include:

  • Molecular Biology
  • Genetics
  • Immunology
  • Cancer Research
  • Surgery

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

    Struan F. A. Grant;Gudmar Thorleifsson;Inga Reynisdottir;Rafil Benediktsson

  • PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

    Kai Wang;Mingyao Li;Dexter Hadley;Rui Liu

  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

    Joseph T. Glessner;Kai Wang;Guiqing Cai;Olena Korvatska

  • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

    Anna Helgadottir;Andrei Manolescu;Gudmar Thorleifsson;Solveig Gretarsdottir

  • Common genetic variants on 5p14.1 associate with autism spectrum disorders

    Kai Wang;Haitao Zhang;Deqiong Ma;Maja Bucan

  • Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene.

    Struan F. A. Grant;David M. Reid;Glen Blake;Ruth Herd

  • A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

    Hakon Hakonarson;Struan F A Grant;Jonathan P. Bradfield;Luc Marchand

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

    Agnar Helgason;Snæbjörn Pálsson;Snæbjörn Pálsson;Gudmar Thorleifsson;Struan F A Grant;Struan F A Grant

  • Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes

    J. Elia;X. Gai;H. M. Xie;J. C. Perin

  • A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality

    Val Mann;Emma E. Hobson;Baohua Li;Tracy L. Stewart

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • Relation of alleles of the collagen type Ialpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women

    A. G. Uitterlinden;H. Burger;Qiuju Huang;Fang Yue

  • Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

    Maja Bucan;Brett S. Abrahams;Kai Wang;Joseph T. Glessner

  • Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies

    Brendan J. Keating;Sam Tischfield;Sam Tischfield;Sarah S. Murray;Tushar Bhangale

  • A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction.

    Anna Helgadottir;Andrei Manolescu;Agnar Helgason;Gudmar Thorleifsson

  • Copy number variation at 1q21.1 associated with neuroblastoma

    Sharon J. Diskin;Cuiping Hou;Joseph T. Glessner;Edward F. Attiyeh;Edward F. Attiyeh

  • High-resolution mapping and analysis of copy number variations in the human genome: A data resource for clinical and research applications

    Tamim H. Shaikh;Xiaowu Gai;Juan C. Perin;Joseph T. Glessner

Frequent Co-Authors

Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Jonathan P. Bradfield
Jonathan P. Bradfield Children's Hospital of Philadelphia
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia
Babette S. Zemel
Babette S. Zemel Children's Hospital of Philadelphia
Andrew D. Wells
Andrew D. Wells Children's Hospital of Philadelphia
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Rosetta M. Chiavacci
Rosetta M. Chiavacci Children's Hospital of Philadelphia
Mads Melbye
Mads Melbye University of Copenhagen
Hans Bisgaard
Hans Bisgaard University of Copenhagen

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