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Microbiology

D-Index
63
Citations
13022
World Ranking
2758
National Ranking
243

Research.com Recognitions

  • 2008 - Member of Academia Europaea

Overview

Peter O'Hare is affiliated with Imperial College London in the United Kingdom and has an active research profile in medicine, particularly focused on immunology, microbiology, and epidemiology. Their work encompasses various aspects of viral infections, immune responses, and neurological conditions linked to infectious diseases.

The main fields of study for this scientist include:

  • Medicine
  • Immunology and Microbiology

The subfields of study reflect specialized areas within these disciplines:

  • Epidemiology
  • Immunology
  • Infectious Diseases
  • Genetics
  • Neurology

Their primary research focuses on viral infections and immune system interactions, with major topics including:

  • Herpesvirus Infections and Treatments
  • Interferon and Immune Responses
  • Cytomegalovirus and Herpesvirus Research
  • Viral Infections and Vectors
  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Lymphoma Diagnosis and Treatment

Recent publications by Peter O'Hare cover a range of virology and neuro-oncology topics. Notable papers include:

  • "HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection" (2020) published in The Journal of Experimental Medicine
  • "pUL36 Deubiquitinase Activity Augments Both the Initiation and the Progression of Lytic Herpes Simplex Virus Infection in IFN-Primed Cells" (2022) published in Journal of Virology
  • "Regarding "Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma"" (2020) published in Neuro-Oncology Practice
  • "Evasion of Innate Cytosolic DNA Sensing by a Gammaherpesvirus Facilitates Establishment of Latent Infection" (2020) published by UNC Libraries
  • "Investigating the effect of Herpes Simplex Virus 1 Latency-Associated Non-Coding RNAs on the Human Neuronal Transcriptome" (2020) published in Access Microbiology

Frequent co-authors collaborating with Peter O'Hare include:

  • Beate Sodeik
  • Chenglong Sun
  • Søren R. Paludan
  • Jonas Mohnke
  • Irmgard Stark

The scientist's work has been published in diverse venues, demonstrating interdisciplinary engagement:

  • The Journal of Experimental Medicine
  • Journal of Virology
  • Neuro-Oncology Practice
  • UNC Libraries
  • Access Microbiology

Recognition for Peter O'Hare's contributions includes election as a Member of Academia Europaea in 2008.

Best Publications

  • Intercellular trafficking and protein delivery by a herpesvirus structural protein.

    Gillian Elliott;Peter O'Hare

  • Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters.

    P O'Hare;G S Hayward

  • Intercellular delivery of functional p53 by the herpesvirus protein VP22.

    Anne Phelan;Gill Elliott;Peter O'Hare

  • Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

    P. O'Hare;C.R. Goding

  • Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation.

    P O'Hare;G S Hayward

  • Three functional classes of transcriptional activation domain.

    Justin Blau;Hua Xiao;Susan McCracken;Peter O'Hare

  • trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus.

    M C Pizzorno;P O'Hare;L Sha;R L LaFemina

  • Live-cell analysis of a green fluorescent protein-tagged herpes simplex virus infection.

    Gillian Elliott;Peter O’Hare

  • Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.

    Daniel Bailey;Peter O'Hare

  • VP16 interacts via its activation domain with VP22, a tegument protein of herpes simplex virus, and is relocated to a novel macromolecular assembly in coexpressing cells.

    G Elliott;G Mouzakitis;P O'Hare

  • Herpes Simplex Virus Type 1 Tegument Protein VP22 Induces the Stabilization and Hyperacetylation of Microtubules

    Gillian Elliott;Peter O’Hare

  • The virion transactivator of herpes simplex virus

    P. O'Hare

  • Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein.

    M S Roberts;A Boundy;P O'Hare;M C Pizzorno

  • Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor.

    R Lu;P Yang;P O'Hare;V Misra

  • Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression.

    P. O'Hare;C. R. Goding;A. Haigh

  • Intercellular trafficking of VP22-GFP fusion proteins.

    G Elliott;P O'Hare

  • Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis

    Camilo Raggo;Noreen Rapin;Julie Stirling;Philipe Gobeil

  • Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22

    M. S. Dilber;A. Phelan;A. Aints;A. J. Mohamed

  • Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.

    A H Batchelor;P O'Hare

  • Delivery of substances to cells

    Peter Francis Joseph O'hare;Nadia Michelle Normand

Frequent Co-Authors

Gary S. Hayward
Gary S. Hayward Johns Hopkins University
Søren R. Paludan
Søren R. Paludan Aarhus University
Colin R. Goding
Colin R. Goding University of Oxford
Edward W. Tate
Edward W. Tate Imperial College London
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Bryan T. Grenfell
Bryan T. Grenfell Princeton University
Ren Sun
Ren Sun University of California, Los Angeles
Blossom Damania
Blossom Damania University of North Carolina at Chapel Hill
John McLauchlan
John McLauchlan University of Glasgow
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School

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