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Microbiology

D-Index
72
Citations
18164
World Ranking
1757
National Ranking
748

Overview

Ren Sun is a researcher affiliated with the University of California, Los Angeles, specializing in the field of Medicine. Their work primarily spans the study of Infectious Diseases, Epidemiology, Molecular Biology, Oncology, and Biomedical Engineering.

Their research covers several key topics including:

  • SARS-CoV-2 and COVID-19 Research
  • Cytomegalovirus and herpesvirus research
  • Viral-associated cancers and disorders
  • COVID-19 Clinical Research Studies
  • Cancer Cells and Metastasis
  • Genetic factors in colorectal cancer
  • Mosquito-borne diseases and control

Ren Sun has contributed to several recent publications that reflect the diversity and focus of their research. Significant papers include:

  • "Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing" (2020, Nature)
  • "A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns" (2020, Nature Communications)
  • "Clofazimine broadly inhibits coronaviruses including SARS-CoV-2" (2021, Nature)
  • "Sex differences in oncogenic mutational processes" (2020, Nature Communications)
  • "A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals" (2020, bioRxiv [Cold Spring Harbor Laboratory])

The researcher frequently publishes in several venues, with notable contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature
  • UNC Libraries
  • Cancer Research

Collaborative efforts define a significant part of Ren Sun's work. Frequent co-authors include:

  • Yushen Du
  • Kwok-Yung Yuen
  • Shuofeng Yuan
  • Paul C. Boutros
  • Nolan Ung

Their research incorporates a broad interdisciplinary approach spanning from fundamental molecular biology to clinical research studies, particularly emphasizing the molecular mechanisms of infectious diseases and cancer. This multidisciplinary strategy supports investigations into both viral infections such as SARS-CoV-2 and oncogenic processes contributing to cancer biology.

Best Publications

  • IRF3 mediates a TLR3/TLR4-specific antiviral gene program

    Sean E. Doyle;Sagar A. Vaidya;Ryan O'Connell;Hajir Dadgostar

  • Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.

    Laura Riva;Shuofeng Yuan;Xin Yin;Laura Martin-Sancho

  • A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus.

    Ren Sun;Su-Fang Lin;Lyndle Gradoville;Yan Yuan

  • Kinetics of Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression

    Ren Sun;Su Fang Lin;Su Fang Lin;Katherine Staskus;Lyndle Gradoville

  • Fluorescent Imaging of Single Nanoparticles and Viruses on a Smart Phone

    Qingshan Wei;Hangfei Qi;Wei Luo;Derek Tseng

  • Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

    Autumn G. York;Kevin J. Williams;Joseph P. Argus;Quan D. Zhou

  • A Comprehensive Biophysical Description of Pairwise Epistasis throughout an Entire Protein Domain

    C. Anders Olson;Nicholas C. Wu;Ren Sun

  • Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

    Momoko Watanabe;Jessie E. Buth;Neda Vishlaghi;Luis de la Torre-Ubieta

  • 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model

    Chunfeng Li;Yong-Qiang Deng;Shuo Wang;Feng Ma;Feng Ma

  • Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells.

    G Miller;L Heston;E Grogan;L Gradoville

  • The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum.

    Sonal Srikanth;Jin Seok Woo;Beibei Wu;Yasser M. El-Sherbiny;Yasser M. El-Sherbiny;Yasser M. El-Sherbiny

  • Adaptation in protein fitness landscapes is facilitated by indirect paths

    Nicholas C Wu;Lei Dai;C Anders Olson;James O Lloyd-Smith

  • Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection.

    George Miller;Michael O. Rigsby;Lee Heston;Elizabeth Grogan

  • NF-κB Inhibits Gammaherpesvirus Lytic Replication

    Helen J. Brown;Moon Jung Song;Hongyu Deng;Ting Ting Wu

  • Cellular Tropism and Viral Interleukin-6 Expression Distinguish Human Herpesvirus 8 Involvement in Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman’s Disease

    Katherine A. Staskus;Ren Sun;George Miller;Paul Racz

  • Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirus.

    Ren Sun;Su-Fang Lin;Lyn Gradoville;George Miller

  • The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.

    Oscar Gonzalez;Vanessa Fontanes;Santanu Raychaudhuri;Rachel Loo

  • Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm

    Pak Kin Wong;Fuqu Yu;Arash Shahangian;Genhong Cheng

  • Genetic Analysis of H1N1 Influenza Virus from Throat Swab Samples in a Microfluidic System for Point-of-Care Diagnostics

    B. Scott Ferguson;Steven F. Buchsbaum;Ting-Ting Wu;Kuangwen Hsieh

  • Label-Free, Electrical Detection of the SARS Virus N-Protein with Nanowire Biosensors Utilizing Antibody Mimics as Capture Probes

    Fumiaki N. Ishikawa;Hsiao Kang Chang;Marco Curreli;Hsiang I. Liao

  • Author response: Adaptation in protein fitness landscapes is facilitated by indirect paths

    Nicholas C Wu;Lei Dai;C Anders Olson;James O Lloyd-Smith

Frequent Co-Authors

Nicholas C. Wu
Nicholas C. Wu Scripps Research Institute
James O. Lloyd-Smith
James O. Lloyd-Smith University of California, Los Angeles
Z. Hong Zhou
Z. Hong Zhou University of California, Los Angeles
Alexander Zelikovsky
Alexander Zelikovsky Georgia State University
Genhong Cheng
Genhong Cheng University of California, Los Angeles
Eleazar Eskin
Eleazar Eskin University of California, Los Angeles
Sumit K. Chanda
Sumit K. Chanda Discovery Institute
George Miller
George Miller Yale University
Marcia A. Blackman
Marcia A. Blackman Trudeau Institute
Otto O. Yang
Otto O. Yang University of California, Los Angeles

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