D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 67 Citations 17,395 163 World Ranking 1397 National Ranking 617

Research.com Recognitions

Awards & Achievements

2012 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Virus
  • Genetics

His primary scientific interests are in Virology, Antibody, Genetics, Virus and Mutation. His research ties Antigen and Virology together. His work in Epitope, Neutralizing antibody and Serology are all subfields of Antibody research.

Jesse D. Bloom combines subjects such as Polyclonal antibodies and Severe acute respiratory syndrome coronavirus 2 with his study of Epitope. His Genetics study integrates concerns from other disciplines, such as Evolutionary biology and Protein structure. His Mutation research includes themes of Plasma protein binding, Computational biology, Influenza A virus and Binding site.

His most cited work include:

  • Protein stability promotes evolvability. (818 citations)
  • Why highly expressed proteins evolve slowly (651 citations)
  • Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance (499 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Virology, Virus, Antibody, Epitope and Genetics. His research integrates issues of Mutation, Viral evolution, Immunity and Polyclonal antibodies in his study of Virology. His Mutation course of study focuses on Plasma protein binding and Binding site.

His work deals with themes such as Antigen and Severe acute respiratory syndrome coronavirus 2, which intersect with Antibody. His studies deal with areas such as Lineage, Viral entry and In vitro as well as Epitope. His work carried out in the field of Neutralization brings together such families of science as HEK 293 cells and Coronavirus.

He most often published in these fields:

  • Virology (110.54%)
  • Virus (79.55%)
  • Antibody (85.62%)

What were the highlights of his more recent work (between 2020-2021)?

  • Virology (110.54%)
  • Antibody (85.62%)
  • Epitope (62.30%)

In recent papers he was focusing on the following fields of study:

Jesse D. Bloom mainly focuses on Virology, Antibody, Epitope, Severe acute respiratory syndrome coronavirus 2 and Antigen. His Virology research is multidisciplinary, incorporating perspectives in Viral evolution, Mutant and Polyclonal antibodies. His Antibody study incorporates themes from Immune system and Immunity.

Jesse D. Bloom usually deals with Epitope and limits it to topics linked to Mutation and Protein domain and Plasma protein binding. His Severe acute respiratory syndrome coronavirus 2 research includes elements of Computational biology and Coronavirus. The various areas that Jesse D. Bloom examines in his Virus study include Cell culture and Germline.

Between 2020 and 2021, his most popular works were:

  • Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition. (185 citations)
  • Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition. (185 citations)
  • Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition. (185 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • Genetics

His primary areas of investigation include Antibody, Epitope, Virology, Virus and Mutation. Jesse D. Bloom combines subjects such as Protein domain, Immunity and Severe acute respiratory syndrome coronavirus 2 with his study of Antibody. The concepts of his Protein domain study are interwoven with issues in Plasma protein binding, Immunization and Monoclonal.

His biological study spans a wide range of topics, including Titer and Coronavirus. His work in Virus addresses issues such as Polyclonal antibodies, which are connected to fields such as Neutralization, Antigen binding and Binding site. His Monoclonal antibody research includes themes of Viral evolution, Lineage, Rational design, Antigen and Coronavirus disease 2019.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

Tyler N. Starr;Allison J. Greaney;Allison J. Greaney;Sarah K. Hilton;Sarah K. Hilton;Daniel Ellis.
Cell (2020)

1263 Citations

Protein stability promotes evolvability.

Jesse D. Bloom;Sy T. Labthavikul;Christopher R. Otey;Frances H. Arnold.
Proceedings of the National Academy of Sciences of the United States of America (2006)

1145 Citations

Why highly expressed proteins evolve slowly

D. Allan Drummond;Jesse D. Bloom;Christoph Adami;Christoph Adami;Claus O. Wilke;Claus O. Wilke.
Proceedings of the National Academy of Sciences of the United States of America (2005)

830 Citations

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition.

Allison J. Greaney;Allison J. Greaney;Tyler N. Starr;Pavlo Gilchuk;Seth J. Zost.
Cell Host & Microbe (2021)

706 Citations

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

Jesse D. Bloom;Lizhi Ian Gong;David Baltimore.
Science (2010)

698 Citations

Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays.

Katharine H D Crawford;Katharine H D Crawford;Rachel Eguia;Adam S Dingens;Andrea N Loes.
Viruses (2020)

529 Citations

In the light of directed evolution: pathways of adaptive protein evolution.

Jesse D. Bloom;Frances H. Arnold.
Proceedings of the National Academy of Sciences of the United States of America (2009)

482 Citations

Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate.

Amin Addetia;Katharine H.D. Crawford;Katharine H.D. Crawford;Adam Dingens;Haiying Zhu.
Journal of Clinical Microbiology (2020)

441 Citations

Evolving strategies for enzyme engineering.

Jesse D Bloom;Michelle M Meyer;Peter Meinhold;Christopher R Otey.
Current Opinion in Structural Biology (2005)

438 Citations

Thermodynamic prediction of protein neutrality

Jesse D. Bloom;Jonathan J. Silberg;Claus O. Wilke;D. Allan Drummond.
Proceedings of the National Academy of Sciences of the United States of America (2005)

365 Citations

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