2019 - Fellow of American Physical Society (APS) Citation For discovering that biophysical constraints are a primary driver of protein sequence evolution
Claus O. Wilke mostly deals with Genetics, Evolutionary biology, Gene, Robustness and Saccharomyces cerevisiae. Claus O. Wilke works mostly in the field of Genetics, limiting it down to concerns involving Protein folding and, occasionally, Protein structure. His Evolutionary biology research is multidisciplinary, relying on both Population genetics, Viral quasispecies, Sequence, Range and Neutral network.
His research in Gene intersects with topics in Viral disease, Lentivirus and T lymphocyte. His Robustness research is multidisciplinary, incorporating elements of Survival of the fittest, Biological evolution, Avida, Genotype and Lattice protein. As part of the same scientific family, Claus O. Wilke usually focuses on Protein sequencing, concentrating on Phylogenetics and intersecting with Adaptation.
The scientist’s investigation covers issues in Genetics, Evolutionary biology, Computational biology, Gene and Mutation rate. His Genetics course of study focuses on Protein structure and Biological system. His work in Evolutionary biology addresses issues such as Fitness landscape, which are connected to fields such as Evolutionary dynamics.
When carried out as part of a general Gene research project, his work on Start codon and Saccharomyces cerevisiae is frequently linked to work in Context, therefore connecting diverse disciplines of study. His Mutation rate study incorporates themes from Statistical physics, Viral quasispecies, Mutation and Robustness. His work carried out in the field of Genome brings together such families of science as Bacteriophage, Gene expression and Virulence.
His primary areas of study are Computational biology, Genome, Gene, Evolutionary biology and Epistasis. Claus O. Wilke interconnects Bacteriophage, Gene expression and Virulence in the investigation of issues within Genome. His study on Virulence is covered under Genetics.
His research in Gene tackles topics such as Vibrio cholerae which are related to areas like Horizontal gene transfer, Model organism, Transposable element, DNA sequencing and Network analysis. Claus O. Wilke combines subjects such as Biological system, Protein evolution, Protein structure, Coupling and Small population size with his study of Epistasis. His study looks at the relationship between Small population size and topics such as Robustness, which overlap with Mutation rate.
Claus O. Wilke focuses on Evolutionary biology, Functional divergence, In silico, Gene and Color model. His work in the fields of Evolutionary biology, such as Function, overlaps with other areas such as Context. His work deals with themes such as Genome evolution, Selection, Adaptation and Gene duplication, Neofunctionalization, which intersect with Function.
Claus O. Wilke integrates Context and Saccharomyces cerevisiae in his research. His Bacteriophage, Gene expression, Genome, Codon usage bias and Transcription study are his primary interests in Gene. His research integrates issues of RGB color model, Coding, Hue and Categorical variable in his study of Statistical graphics.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Welcome to the Tidyverse
Hadley Wickham;Mara Averick;Jennifer Bryan;Winston Chang.
The Journal of Open Source Software (2019)
Mistranslation-Induced Protein Misfolding as a Dominant Constraint on Coding-Sequence Evolution
D. Allan Drummond;Claus O. Wilke.
Cell (2008)
Why highly expressed proteins evolve slowly
D. Allan Drummond;Jesse D. Bloom;Christoph Adami;Christoph Adami;Claus O. Wilke;Claus O. Wilke.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Evolution of digital organisms at high mutation rates leads to survival of the flattest
Claus O. Wilke;Jia Lan Wang;Charles Ofria;Richard E. Lenski.
Nature (2001)
The evolutionary consequences of erroneous protein synthesis
D. Allan Drummond;Claus O. Wilke.
Nature Reviews Genetics (2009)
A Single Determinant Dominates the Rate of Yeast Protein Evolution
D. Allan Drummond;Alpan Raval;Alpan Raval;Claus O. Wilke.
Molecular Biology and Evolution (2006)
Avida: a software platform for research in computational evolutionary biology
Charles Ofria;Claus O. Wilke.
Artificial Life (2004)
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
Aashiq H. Kachroo;Jon M. Laurent;Christopher M. Yellman;Austin G. Meyer.
Science (2015)
Residual Human Immunodeficiency Virus Type 1 Viremia in Some Patients on Antiretroviral Therapy Is Dominated by a Small Number of Invariant Clones Rarely Found in Circulating CD4+ T Cells
Justin R. Bailey;Ahmad R. Sedaghat;Tara Kieffer;Timothy Brennan.
Journal of Virology (2006)
Thermodynamic prediction of protein neutrality
Jesse D. Bloom;Jonathan J. Silberg;Claus O. Wilke;D. Allan Drummond.
Proceedings of the National Academy of Sciences of the United States of America (2005)
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