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Immunology

D-Index
121
Citations
57765
World Ranking
323
National Ranking
205

Medicine

D-Index
121
Citations
57771
World Ranking
3590
National Ranking
1981

Research.com Recognitions

  • 2020 - Fellow of the American Academy of Arts and Sciences
  • 2017 - Member of the National Academy of Sciences
  • 2017 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert F. Siliciano is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily focuses on HIV, contributing extensively to the fields of immunology, microbiology, and medicine. The scientist's work spans subfields such as virology, immunology, infectious diseases, epidemiology, and molecular biology.

Throughout their career, Robert F. Siliciano has explored several main research topics, including:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • HIV/AIDS Drug Development and Treatment
  • HIV/AIDS Research and Interventions
  • Cytomegalovirus and Herpesvirus Research
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research

The scientist has published frequently in various academic venues. Key venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Proceedings of the National Academy of Sciences
  • Science Translational Medicine
  • The Journal of Infectious Diseases

Prominent recent papers authored by or involving Robert F. Siliciano include:

  • Distinct viral reservoirs in individuals with spontaneous control of HIV-1, 2020, Nature
  • Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy, 2020, JCI Insight
  • Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo, 2020, Journal of Clinical Investigation
  • Recommendations for measuring HIV reservoir size in cure-directed clinical trials, 2020, Nature Medicine
  • Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA, 2020, Proceedings of the National Academy of Sciences

Frequent collaborators in Robert F. Siliciano's research include:

  • Janet D. Siliciano
  • Francesco R. Simonetti
  • Steven G. Deeks
  • Emily J. Fray
  • Luis J. Montaner

Robert F. Siliciano has been recognized by several professional organizations. Awards and memberships include:

  • Fellow of the American Academy of Arts and Sciences, 2020
  • Member of the National Academy of Sciences, 2017
  • Member of the National Academy of Medicine (NAM), 2017
  • Member of the Association of American Physicians

Best Publications

  • Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

    Diana Finzi;Monika Hermankova;Theodore Pierson;Lucy M. Carruth

  • Latent infection of CD4 + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

    Diana Finzi;Joel N Blankson;Janet M Siliciano;Joseph Bernard Margolick

  • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

    Tae Wook Chun;Lucy Carruth;Diana Finzi;Xuefei Shen

  • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

    Janet D Siliciano;Joleen Kajdas;Diana Finzi;Thomas C Quinn;Thomas C Quinn

  • Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

    Ya Chi Ho;Liang Shan;Nina N. Hosmane;Jeffrey Wang

  • In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency

    Tae Wook Chun;Diana Finzi;Joseph Margolick;Karen Chadwick

  • The challenge of viral reservoirs in HIV-1 infection.

    Joel N. Blankson;Deborah Persaud;Robert F. Siliciano

  • Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

    Liang Shan;Kai Deng;Neeta S. Shroff;Christine M. Durand

  • Defective proviruses rapidly accumulate during acute HIV-1 infection.

    Katherine M. Bruner;Alexandra J. Murray;Ross A. Pollack;Mary G. Soliman

  • Reservoirs for HIV-1: Mechanisms for Viral Persistence in the Presence of Antiviral Immune Responses and Antiretroviral Therapy

    Theodore Pierson;Justin McArthur;Robert F. Siliciano

  • A quantitative approach for measuring the reservoir of latent HIV-1 proviruses

    Katherine M. Bruner;Katherine M. Bruner;Zheng Wang;Francesco R. Simonetti;Alexandra M. Bender

  • Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

    Susanne Eriksson;Erin H. Graf;Viktor Dahl;Matthew C. Strain

  • Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

    Kai Deng;Mihaela Pertea;Anthony Rongvaux;Leyao Wang

  • New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

    C Korin Bullen;Gregory M Laird;Christine M Durand;Janet D Siliciano

  • A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.

    Rebecca E. Hussey;Neil E. Richardson;Mark Kowalski;Nicholas R. Brown

  • Redefining the Viral Reservoirs that Prevent HIV-1 Eradication

    Evelyn Eisele;Robert F. Siliciano;Robert F. Siliciano

  • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

    J. B. Dinoso;S. Y. Kim;A. M. Wiegand;S. E. Palmer;S. E. Palmer

  • Intermittent HIV-1 Viremia (Blips) and Drug Resistance in Patients Receiving HAART

    Richard E. Nettles;Tara L. Kieffer;Tara L. Kieffer;Patty Kwon;Daphne Monie

  • HIV-1 Integration Landscape during Latent and Active Infection

    Lillian B. Cohn;Israel T. Silva;Israel T. Silva;Thiago Y. Oliveira;Rafael A. Rosales

  • Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion.

    Robert F. Siliciano;Robert F. Siliciano;Trebor Lawton;Cindy Knall;Robert W. Karr

  • HIV latency.

    Unknown

Frequent Co-Authors

Janet D. Siliciano
Janet D. Siliciano Johns Hopkins University School of Medicine
Joel N. Blankson
Joel N. Blankson Johns Hopkins University School of Medicine
Thomas C. Quinn
Thomas C. Quinn Johns Hopkins University
Joseph B. Margolick
Joseph B. Margolick Johns Hopkins University
Steven G. Deeks
Steven G. Deeks University of California, San Francisco
Stuart C. Ray
Stuart C. Ray Johns Hopkins University School of Medicine
Hung-Chih Yang
Hung-Chih Yang National Taiwan University
Ellis L. Reinherz
Ellis L. Reinherz Harvard University
Bruce D. Walker
Bruce D. Walker Harvard University
Christopher B. Buck
Christopher B. Buck National Institutes of Health

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