World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
15495
World Ranking
7102
National Ranking
248

Overview

Hannu Larjava is affiliated with the University of British Columbia in Canada and has focused their research primarily in the fields of Dentistry and Medicine. Their work spans several subfields including Urology, Oral Surgery, Periodontics, Orthodontics, and Pharmacy.

Their research covers a range of topics related to oral health and dental treatments, with a strong emphasis on periodontal regeneration and treatments, oral microbiology and periodontitis research, dental implant techniques and outcomes, dental materials and restorations, as well as oral and gingival health research. They have also contributed to research in oral and maxillofacial pathology and bone and dental protein studies.

Hannu Larjava's recent publications include:

  • Leucocyte- and platelet-rich fibrin regulates expression of genes related to early wound healing in human gingival fibroblasts, 2020, Journal Of Clinical Periodontology
  • Decontamination of rough implant surfaces colonized by multispecies oral biofilm by application of leukocyte- and platelet-rich fibrin, 2020, Journal of Periodontology
  • Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures, 2023, Scientific Reports
  • Decontamination of multispecies oral biofilm from rough implant surface by airflow with glycine, 2021, Clinical and Experimental Dental Research
  • Scanning electron microscopic analysis of adherent bacterial biofilms associated with peri-implantitis, 2023, Clinical and Experimental Dental Research

The venues where Hannu Larjava has frequently published include:

  • Scientific Reports
  • Clinical and Experimental Dental Research
  • Journal Of Clinical Periodontology
  • Journal of Periodontology
  • American Journal of Preventive Cardiology

Among frequent collaborators, Hannu Larjava has worked multiple times with Lari Häkkinen, Jiarui Bi, Leeni Koivisto, Gethin Owen, and Guoqiao Jiang.

Best Publications

  • The Activation and Function of Host Matrix Metalloproteinases in Dentin Matrix Breakdown in Caries Lesions

    L. Tjäderhane;H. Larjava;T. Sorsa;V.-J. Uitto

  • Expression of matrix metalloproteinase-2 and -9 during early human wound healing

    T Salo;M Mäkelä;M Kylmäniemi;H Autio-Harmainen

  • Expression of integrins and basement membrane components by wound keratinocytes.

    H Larjava;T Salo;K Haapasalmi;R H Kramer

  • Novel function for beta 1 integrins in keratinocyte cell-cell interactions.

    H Larjava;J Peltonen;S K Akiyama;S S Yamada

  • Integrin-mediated cell adhesion to type I collagen fibrils.

    Johanna Jokinen;Elina Dadu;Petri Nykvist;Jarmo Käpylä

  • Matrix Metalloproteinases (MMP-2 and MMP-9) of the Oral Cavity: Cellular Origin and Relationship to Periodontal Status:

    M. Makela;T. Salo;V.-J. Uitto;H. Larjava

  • Cell biology of gingival wound healing.

    Lari Häkkinen;Veli-Jukka Uitto;Hannu Larjava

  • Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes.

    T Salo;J G Lyons;F Rahemtulla;H Birkedal-Hansen

  • Expression of proteoglycans and hyaluronan during wound healing.

    O Oksala;T Salo;R Tammi;L Häkkinen

  • Differential regulation of extracellular matrix proteoglycan (PG) gene expression. Transforming growth factor-beta 1 up-regulates biglycan (PGI), and versican (large fibroblast PG) but down-regulates decorin (PGII) mRNA levels in human fibroblasts in culture.

    Veli-Matti Kahari;H. Larjava;J. Uitto

  • Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

    J Peltonen;H Larjava;S Jaakkola;H Gralnick

  • Transforming Growth Factor-β Induces Collagenase-3 Expression by Human Gingival Fibroblasts via p38 Mitogen-activated Protein Kinase

    Laura Ravanti;Lari Häkkinen;Hannu Larjava;Ulpu Saarialho-Kere

  • Proteolytic Events of Wound-Healing — Coordinated Interactions Among Matrix Metalloproteinases (MMPs), Integrins, and Extracellular Matrix Molecules

    Bjorn Steffensen;Lari Häkkinen;Hannu Larjava

  • Kindlins: essential regulators of integrin signalling and cell–matrix adhesion

    Hannu Larjava;Edward F Plow;Chuanyue Wu

  • Scarless healing of oral mucosa is characterized by faster resolution of inflammation and control of myofibroblast action compared to skin wounds in the red Duroc pig model

    Karen Mak;Aleem Manji;Aleem Manji;Corrie Gallant-Behm;Corrie Gallant-Behm;Colin Wiebe

  • Wound healing in oral mucosa results in reduced scar formation as compared with skin: Evidence from the red Duroc pig model and humans

    Joyce W. Wong;Corrie Gallant-Behm;Corrie Gallant-Behm;Colin Wiebe;Karen Mak

  • Regulation of Fibroblast Migration on Collagenous Matrix by a Cell Surface Peptidase Complex

    Giulio Ghersi;Huan Dong;Leslie A. Goldstein;Yunyun Yeh

  • Integrins in Wound Healing

    Leeni Koivisto;Jyrki Heino;Lari Häkkinen;Hannu Larjava

  • Differential expression of matrilysin‐1 (MMP‐7), 92 kD gelatinase (MMP‐9), and metalloelastase (MMP‐12) in oral verrucous and squamous cell cancer

    U Impola;V J Uitto;J Hietanen;L Hakkinen

  • Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes.

    Marja Mäkelä;Hannu Larjava;Emma Pirilä;Päivi Maisi

Frequent Co-Authors

Jyrki Heino
Jyrki Heino University of Turku
Tuula Salo
Tuula Salo University of Helsinki
Veli-Jukka Uitto
Veli-Jukka Uitto University of Helsinki
Kenneth M. Yamada
Kenneth M. Yamada National Institutes of Health
Chuanyue Wu
Chuanyue Wu University of Pittsburgh
Veli-Matti Kähäri
Veli-Matti Kähäri Turku University Hospital
Steven K. Akiyama
Steven K. Akiyama National Institutes of Health
Eero Vuorio
Eero Vuorio University of Turku
Timo Sorsa
Timo Sorsa University of Helsinki
Markku Jalkanen
Markku Jalkanen Faron Pharmaceuticals

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