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Markku Jalkanen

Markku Jalkanen

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
11448
World Ranking
15011
National Ranking
107

Overview

Markku Jalkanen is affiliated with Faron Pharmaceuticals in Finland and has contributed to research primarily in the fields of Medicine and Immunology and Microbiology. The scientist's work covers several subfields including Immunology, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, Oncology, and Critical Care and Intensive Care Medicine.

The main topics of Markku Jalkanen's research include:

  • Immune cells in cancer
  • Respiratory Support and Mechanisms
  • Monoclonal and Polyclonal Antibodies Research
  • Intensive Care Unit Cognitive Disorders
  • Cardiac Arrest and Resuscitation
  • Galectins and Cancer Biology
  • Immunotherapy and Immune Responses

Key recent papers by this scientist and their publication details are:

  • Effect of Intravenous Interferon β-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome, 2020, JAMA
  • Nonclinical Characterization of Bexmarilimab, a Clever-1-Targeting Antibody for Supporting Immune Defense Against Cancers, 2022, Molecular Cancer Therapeutics
  • Immune activation in first-in-human anti-macrophage antibody (anti-Clever-1 mAb; FP-1305) phase I/II MATINS trial: Part I dose-escalation, safety, and efficacy results, 2020, Journal of Clinical Oncology
  • Glucocorticoids inhibit type I IFN beta signaling and the upregulation of CD73 in human lung, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • 1024MO A phase I/II MATINS trial: Part 1 pharmacokinetic, safety and efficacy results of Clever-1 blockade in advanced cancer, 2020, Annals of Oncology

Frequent co-authors collaborating with Markku Jalkanen include:

  • Matti K. Karvonen
  • Sirpa Jalkanen
  • Maija Hollmén
  • Jami Mandelin
  • V. Marco Ranieri

The scientist's publications have appeared in various journals including:

  • JAMA
  • Molecular Cancer Therapeutics
  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of Oncology

Best Publications

  • Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin.

    Sirpa Jalkanen;Markku Jalkanen

  • Molecular cloning of syndecan, an integral membrane proteoglycan.

    Scott Saunders;M. Jalkanen;S. O'Farrell;M. Bernfield

  • Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.

    A Rapraeger;M Jalkanen;M Bernfield

  • The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.

    A Rapraeger;M Jalkanen;E Endo;J Koda

  • Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis

    T.A. Mitsiadis;M. Salmivirta;T. Muramatsu;H. Muramatsu

  • Expression of proteoglycans and hyaluronan during wound healing.

    O Oksala;T Salo;R Tammi;L Häkkinen

  • Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

    S Jalkanen;M Jalkanen;R Bargatze;M Tammi

  • Induced expression of syndecan in healing wounds.

    K Elenius;S Vainio;M Laato;M Salmivirta

  • Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

    M Jalkanen;H Nguyen;A Rapraeger;N Kurn

  • Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain.

    M Jalkanen;A Rapraeger;S Saunders;M Bernfield

  • Syndecan from embryonic tooth mesenchyme binds tenascin.

    M Salmivirta;K Elenius;S Vainio;U Hofer

  • Syndecan and tenascin expression is induced by epithelial-mesenchymal interactions in embryonic tooth mesenchyme.

    S Vainio;M Jalkanen;I Thesleff

  • Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans.

    M Mali;P Jaakkola;A M Arvilommi;M Jalkanen

  • Syndecan expression regulates cell morphology and growth of mouse mammary epithelial tumor cells.

    Sirpa Leppa;Markku Mali;Heini M. Miettinen;Markku Jalkanen

  • Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis

    Irma Thesleff;Markku Jalkanen;Seppo Vainio;Merton Bernfield

  • Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney.

    Seppo Vainio;Eero Lehtonen;Markku Jalkanen;Merton Bernfield

  • Function of the syndecans--a family of cell surface proteoglycans.

    Klaus Elenius;Markku Jalkanen

  • Growth Factors Induce 3T3 Cells to Express bFGF-binding Syndecan*

    K Elenius;A Määttä;M Salmivirta;M Jalkanen

  • Binding of human syndecan to extracellular matrix proteins.

    K Elenius;M Salmivirta;P Inki;M Mali

  • Syndecan from embryonic tooth mesenchyme binds tenascin

    Markku Jalkanen;Markku Salmivirta;Seppo Vainio;Klaus Elenius

Frequent Co-Authors

Sirpa Jalkanen
Sirpa Jalkanen University of Turku
Klaus Elenius
Klaus Elenius University of Turku
Seppo Vainio
Seppo Vainio University of Oulu
Irma Thesleff
Irma Thesleff University of Helsinki
Merton Bernfield
Merton Bernfield Harvard University
Petri Auvinen
Petri Auvinen University of Helsinki
Alan C. Rapraeger
Alan C. Rapraeger University of Wisconsin–Madison
Hannu Larjava
Hannu Larjava University of British Columbia
Lauri Saxén
Lauri Saxén University of Helsinki
Jyrki Heino
Jyrki Heino University of Turku

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