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Biology and Biochemistry

D-Index
91
Citations
25734
World Ranking
2357
National Ranking
1256

Overview

Allan R. Brasier is affiliated with the University of Wisconsin-Madison in the United States. Their research spans multiple fields, primarily Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, Brasier's work has focused on subfields such as Molecular Biology, Pulmonary and Respiratory Medicine, Epidemiology, Oncology, and Public Health, Environmental and Occupational Health.

The research topics covered by Brasier include:

  • Respiratory viral infections research
  • Protein Degradation and Inhibitors
  • Health and Medical Research Impacts
  • Peptidase Inhibition and Analysis
  • Interdisciplinary Research and Collaboration
  • Asthma and respiratory diseases
  • Immune Cell Function and Interaction

Brasier has contributed to several recent papers, among which are:

  • Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation (2020) published in the Journal of Medicinal Chemistry
  • Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry (2021) published in the Journal of the American Chemical Society
  • Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site (2022) published in the Journal of Medicinal Chemistry
  • Individual and team competencies in translational teams (2020) published in the Journal of Clinical and Translational Science
  • Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis (2020) published in Frontiers in Pharmacology

Frequent co-authors collaborating with Brasier include Jia Zhou, Ying Ge, Morgan Mann, Dianhua Qiao, and Yi Li.

Brasier publishes regularly in a range of journals, with notable frequent publication venues being:

  • Journal of Clinical and Translational Science
  • Frontiers in Immunology
  • Viruses
  • Gastroenterology
  • Nucleic Acids Research

In addition to journal articles, Brasier has contributions to book publications, including a title with Springer Nature: Precision Approaches to Heterogeneity in Asthma (2023).

Best Publications

  • Vascular Inflammation and the Renin-Angiotensin System

    Allan R. Brasier;Adrian Recinos;Mohsen S. Eledrisi

  • Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

    Brasier Ar;Tate Je;Habener Jf

  • The NF-kappaB regulatory network.

    Allan R. Brasier

  • The nuclear factor-κB–interleukin-6 signalling pathway mediating vascular inflammation

    Allan R. Brasier

  • Effects of an online virtual community on customer loyalty and travel product purchases.

    Woo Gon Kim;Chang Lee;Stephen J. Hiemstra

  • Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-κB transcription factors

    Youqi Han;Marschall S. Runge;Allan R. Brasier

  • An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

    Brian C. Tieu;Chang Lee;Hong Sun;Wanda LeJeune

  • Retinoic Acid-Inducible Gene I Mediates Early Antiviral Response and Toll-Like Receptor 3 Expression in Respiratory Syncytial Virus-Infected Airway Epithelial Cells

    Ping Liu;Mohammad Jamaluddin;Kui Li;Roberto P. Garofalo

  • Hungry bone syndrome: Clinical and biochemical predictors of its occurrence after parathyroid surgery

    Allan R. Brasier;Samuel R. Nussbaum

  • Mathematical model of NF- κB regulatory module

    Tomasz Lipniacki;Tomasz Lipniacki;Pawel Paszek;A R Allan R Brasier;Bruce Luxon

  • Nuclear factor-κB-dependent induction of interleukin-8 gene expression by tumor necrosis factor α : Evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation

    Spiros Vlahopoulos;Istvan Boldogh;Antonella Casola;Allan R. Brasier

  • Respiratory Syncytial Virus–Induced Activation of Nuclear Factor–κB in the Lung Involves Alveolar Macrophages and Toll-Like Receptor 4–Dependent Pathways

    Helene A. Haeberle;Ryuta Takizawa;Antonella Casola;Allan R. Brasier

  • Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation

    David E. Nowak;Bing Tian;Allan R. Brasier

  • Identification of Direct Genomic Targets Downstream of the Nuclear Factor-κB Transcription Factor Mediating Tumor Necrosis Factor Signaling

    Bing Tian;David E. Nowak;Mohammad Jamaluddin;Shaofei Wang

  • Tumor Necrosis Factor-α-inducible IκBα Proteolysis Mediated by Cytosolic m-Calpain A MECHANISM PARALLEL TO THE UBIQUITIN-PROTEASOME PATHWAY FOR NUCLEAR FACTOR-κB ACTIVATION

    Youqi Han;Steven Weinman;Istvan Boldogh;Randall K. Walker

  • MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II

    Hariyadarshi Pannu;Van Tran-Fadulu;Christina L. Papke;Steve Scherer

  • Identification of a nuclear factor kappa B-dependent gene network.

    Bing Tian;Allan R. Brasier

  • Expression of Respiratory Syncytial Virus-Induced Chemokine Gene Networks in Lower Airway Epithelial Cells Revealed by cDNA Microarrays

    Yuhong Zhang;Bruce A. Luxon;Antonella Casola;Roberto P. Garofalo

  • Mechanisms for Inducible Control of Angiotensinogen Gene Transcription

    Allan R. Brasier;Junyi Li

  • Drug Discovery Targeting Bromodomain-Containing Protein 4.

    Zhiqing Liu;Pingyuan Wang;Haiying Chen;Eric A. Wold

Frequent Co-Authors

Roberto P. Garofalo
Roberto P. Garofalo The University of Texas Medical Branch at Galveston
Antonella Casola
Antonella Casola The University of Texas Medical Branch at Galveston
Istvan Boldogh
Istvan Boldogh The University of Texas Medical Branch at Galveston
Jia Zhou
Jia Zhou The University of Texas Medical Branch at Galveston
Marek Kimmel
Marek Kimmel Rice University
Sanjiv Sur
Sanjiv Sur The University of Texas Medical Branch at Galveston
Zsolt Radak
Zsolt Radak Waseda University
William J. Calhoun
William J. Calhoun The University of Texas Medical Branch at Galveston
Joel F. Habener
Joel F. Habener Harvard University
David Ron
David Ron University of Cambridge

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