What is he best known for?
The fields of study he is best known for:
His main research concerns Molecular biology, DNA repair, DNA glycosylase, Base excision repair and Nucleotide excision repair.
In his study, which falls under the umbrella issue of Molecular biology, Acetylation and Mutation is strongly linked to DNA.
The DNA repair study combines topics in areas such as Oxidative stress, DNA damage, Mitochondrial DNA and Proliferating cell nuclear antigen.
His work carried out in the field of DNA damage brings together such families of science as Endocrinology, Skeletal muscle and NAD+ kinase, Nicotinamide phosphoribosyltransferase.
DNA glycosylase is a primary field of his research addressed under Biochemistry.
His studies in Nucleotide excision repair integrate themes in fields like DNA mismatch repair and DNA polymerase.
His most cited work include:
- Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. (410 citations)
- Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals (370 citations)
- ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation (274 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Molecular biology, DNA repair, DNA glycosylase, Biochemistry and Oxidative stress.
Chromosome is closely connected to Human cytomegalovirus in his research, which is encompassed under the umbrella topic of Molecular biology.
As a member of one scientific family, Istvan Boldogh mostly works in the field of DNA repair, focusing on DNA damage and, on occasion, Regulation of gene expression.
The study incorporates disciplines such as Cell biology and AP site in addition to DNA glycosylase.
The concepts of his Oxidative stress study are interwoven with issues in Inflammation, Reactive oxygen species and Glutathione.
His study on Reactive oxygen species also encompasses disciplines like
- Immunology together with Aldose reductase, Respiratory epithelium and NADPH oxidase,
- Allergic inflammation which is related to area like NAD+ kinase.
He most often published in these fields:
- Molecular biology (43.80%)
- DNA repair (28.47%)
- DNA glycosylase (27.74%)
What were the highlights of his more recent work (between 2012-2016)?
- Oxidative stress (24.09%)
- DNA repair (28.47%)
- DNA glycosylase (27.74%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Oxidative stress, DNA repair, DNA glycosylase, DNA damage and Biochemistry.
Istvan Boldogh combines subjects such as Reactive oxygen species, In vitro and In vivo with his study of Oxidative stress.
His research integrates issues of Molecular biology, Respiratory epithelium and Cell biology in his study of DNA repair.
His Molecular biology study combines topics from a wide range of disciplines, such as Kinase and DNA replication, Eukaryotic DNA replication.
His studies deal with areas such as Nicotinamide adenine dinucleotide, NAD+ kinase and Endonuclease as well as DNA glycosylase.
The DNA, Glycan, Coactivator and Transcription factor research Istvan Boldogh does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as PARP1, therefore creating a link between diverse domains of science.
Between 2012 and 2016, his most popular works were:
- Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro (109 citations)
- Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins (70 citations)
- Redox-regulating sirtuins in aging, caloric restriction, and exercise. (67 citations)
In his most recent research, the most cited papers focused on:
Istvan Boldogh focuses on DNA glycosylase, DNA repair, DNA damage, Oxidative stress and Biochemistry.
His research in DNA glycosylase intersects with topics in Regulation of gene expression and Nicotinamide adenine dinucleotide, NAD+ kinase.
His Regulation of gene expression research includes elements of Molecular biology, Signal transduction, Proinflammatory cytokine, NEIL1 and Kinase.
His Oxidative stress study incorporates themes from Andrology, Senescence and Pregnancy.
His research investigates the link between Andrology and topics such as Amnion that cross with problems in Immunology.
His study in the fields of DNA, Transcription factor, Coactivator and Endonuclease under the domain of Biochemistry overlaps with other disciplines such as PARP1.
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