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Molecular Biology

D-Index
82
Citations
20529
World Ranking
943
National Ranking
71

Overview

David M. Wilson is a researcher primarily affiliated with AstraZeneca in the United Kingdom. Their work spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. The subfields central to their research include Molecular Biology, Neurology, Oncology, Physiology, and Genetics.

The scientist focuses on several main topics in their research, including:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Amyotrophic Lateral Sclerosis Research
  • Mitochondrial Function and Pathology
  • Cancer therapeutics and mechanisms
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer

Their recent publications include the following papers:

  • "Hallmarks of neurodegenerative diseases" (2023), published in Cell
  • "Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders" (2021), published in Cellular and Molecular Life Sciences
  • "Connecting aging biology and inflammation in the omics era" (2022), published in Journal of Clinical Investigation
  • "Aging and Inflammation" (2023), published in Cold Spring Harbor Perspectives in Medicine
  • "DNA damage repair response in mesenchymal stromal cells: From cellular senescence and aging to apoptosis and differentiation ability" (2020), published in Ageing Research Reviews

Frequent co-authors collaborating with Wilson include:

  • Ashley M. Deacon
  • Matthew A. J. Duncton
  • Debanu Das
  • Patricia Pellicena
  • Kayvan R. Keshari

Wilson has published multiple articles in several journals, with the most common publication venues being:

  • Nature Communications
  • International Journal of Molecular Sciences
  • Nuclear Medicine and Biology
  • UNC Libraries
  • Cellular and Molecular Life Sciences

Best Publications

  • DNA repair mechanisms in dividing and non-dividing cells

    Teruaki Iyama;David M. Wilson

  • The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

    David M Wilson;Daniel Barsky

  • Interaction of human apurinic endonuclease and DNA polymerase β in the base excision repair pathway

    Richard A. O. Bennett;David M. Wilson;Donny Wong;Bruce Demple

  • The mechanics of base excision repair, and its relationship to aging and disease

    David M. Wilson;Vilhelm A. Bohr

  • Overview of Base Excision Repair Biochemistry

    Yun-Jeong Kim;David M. Wilson

  • A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

    Morten Scheibye-Knudsen;Sarah J. Mitchell;Sarah J. Mitchell;Evandro F. Fang;Teruaki Iyama

  • Molecular mechanisms of sister-chromatid exchange.

    David M. Wilson;Larry H. Thompson

  • Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

    Patricia L. Opresko;Jinshui Fan;Shamika Danzy;David M. Wilson

  • Protecting the mitochondrial powerhouse.

    Morten Scheibye-Knudsen;Evandro F. Fang;Deborah L. Croteau;David M. Wilson

  • Life without DNA repair

    David M. Wilson;Larry H. Thompson

  • Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA.

    David M. Wilson;Masaru Takeshita;Arthur P. Grollman;Bruce Demple

  • Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885

    Alastair J. King;Denis R. Patrick;Roberta S. Batorsky;Maureen L. Ho

  • Functional characterization of Ape1 variants identified in the human population.

    Masood Z. Hadi;Matthew A. Coleman;Krzysztof Fidelis;Harvey W. Mohrenweiser

  • XRCC1 co‐localizes and physically interacts with PCNA

    Jinshui Fan;Marit Otterlei;Heng‐Kuan Wong;Alan E. Tomkinson

  • Participation of DNA repair in the response to 5-fluorouracil.

    Michael D. Wyatt;David M. Wilson

  • Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes.

    Harvey W Mohrenweiser;David M Wilson;Irene M Jones

  • Coordination of DNA single strand break repair.

    Rachel Abbotts;David M. Wilson

  • Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

    Pingfang Liu;Limin Qian;Jung-Suk Sung;Nadja C. de Souza-Pinto

  • The RAD2 Domain of Human Exonuclease 1 Exhibits 5′ to 3′ Exonuclease and Flap Structure-specific Endonuclease Activities

    Byung-In Lee;David M. Wilson

  • Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

    Joo Sang Lee;Joo Sang Lee;Lital Adler;Hiren Karathia;Narin Carmel

Frequent Co-Authors

Vilhelm A. Bohr
Vilhelm A. Bohr University of Copenhagen
Anton Simeonov
Anton Simeonov National Institutes of Health
Ajit Jadhav
Ajit Jadhav Pfizer (Germany)
Deborah L. Croteau
Deborah L. Croteau National Institutes of Health
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Bruce Demple
Bruce Demple Stony Brook University
Gianluca Tell
Gianluca Tell University of Udine
Nadja C. de Souza-Pinto
Nadja C. de Souza-Pinto Universidade de São Paulo
Mark R. Kelley
Mark R. Kelley Indiana University
Robert W. Sobol
Robert W. Sobol University of South Alabama

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