D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 11,760 164 World Ranking 9359 National Ranking 4157

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Robert W. Sobol mainly focuses on Base excision repair, DNA repair, Molecular biology, DNA glycosylase and DNA damage. His Base excision repair research is multidisciplinary, incorporating perspectives in Nucleotide excision repair and DNA polymerase. His DNA repair research incorporates elements of Poly ADP ribose polymerase and Genome instability.

His Molecular biology study combines topics in areas such as Knockout mouse, DNA polymerase beta and Proliferating cell nuclear antigen. In his research, Temozolomide is intimately related to DNA mismatch repair, which falls under the overarching field of DNA glycosylase. Within one scientific family, he focuses on topics pertaining to Cell biology under DNA damage, and may sometimes address concerns connected to Biochemistry and Epigenetics.

His most cited work include:

  • Requirement of mammalian DNA polymerase-beta in base-excision repair. (743 citations)
  • Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. (373 citations)
  • Mutation research/fundamental and molecular mechanisms of mutagenesis: special issue: DNA repair and genetic instability. (340 citations)

What are the main themes of his work throughout his whole career to date?

DNA repair, Base excision repair, Molecular biology, DNA damage and Biochemistry are his primary areas of study. His studies deal with areas such as Poly ADP ribose polymerase and Cell biology as well as DNA repair. His Base excision repair research is multidisciplinary, incorporating elements of DNA glycosylase, Nucleotide excision repair, Cancer research and DNA polymerase.

His biological study spans a wide range of topics, including Polymerase, Cisplatin, AP endonuclease, AP site and Proliferating cell nuclear antigen. He has researched DNA damage in several fields, including Computational biology and Gene knockdown. In his study, Enzyme, Nucleotide, Tetramer and Cleavage is strongly linked to Stereochemistry, which falls under the umbrella field of Biochemistry.

He most often published in these fields:

  • DNA repair (43.11%)
  • Base excision repair (41.32%)
  • Molecular biology (32.93%)

What were the highlights of his more recent work (between 2013-2021)?

  • DNA repair (43.11%)
  • DNA damage (31.14%)
  • Cell biology (20.36%)

In recent papers he was focusing on the following fields of study:

Robert W. Sobol mainly investigates DNA repair, DNA damage, Cell biology, Base excision repair and Cancer research. The study incorporates disciplines such as Molecular biology and DNA polymerase in addition to DNA repair. The concepts of his DNA damage study are interwoven with issues in Chromatin, Gene knockdown and Telomere.

Robert W. Sobol interconnects Genome instability, Ubiquitin, DNA and NAD+ kinase in the investigation of issues within Cell biology. His study in Base excision repair is interdisciplinary in nature, drawing from both Cancer, DNA glycosylase and Oligonucleotide. His Cancer research research incorporates themes from Cancer cell, Cell cycle and Kinase.

Between 2013 and 2021, his most popular works were:

  • Mitochondria, energetics, epigenetics, and cellular responses to stress. (139 citations)
  • ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD + depletion (103 citations)
  • A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy (97 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary scientific interests are in DNA damage, DNA repair, Cell biology, Biochemistry and Molecular biology. The various areas that Robert W. Sobol examines in his DNA damage study include Gel electrophoresis and Epigenetics. His research in DNA repair is mostly focused on Base excision repair.

His Base excision repair research is multidisciplinary, relying on both DNA glycosylase, Cancer research and AP site. His work deals with themes such as Oxidative stress, Ubiquitin and DNA, which intersect with Cell biology. His Molecular biology study incorporates themes from Nucleotide excision repair, Nuclear protein, DNA Repair Pathway and DNA mismatch repair.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Requirement of mammalian DNA polymerase-beta in base-excision repair.

Robert W. Sobol;Julie K. Horton;Ralf Kühn;Hua Gu.
Nature (1996)

1073 Citations

Mutation research/fundamental and molecular mechanisms of mutagenesis: special issue: DNA repair and genetic instability.

Kandace Williams;Robert W Sobol.
Mutation Research (2013)

563 Citations

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.

Ping Mao;Kaushal Joshi;Jianfeng Li;Sung Hak Kim.
Proceedings of the National Academy of Sciences of the United States of America (2013)

463 Citations

A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification.

Karen H. Almeida;Robert W. Sobol.
DNA Repair (2007)

461 Citations

The lyase activity of the DNA repair protein β-polymerase protects from DNA-damage-induced cytotoxicity

Robert W. Sobol;Rajendra Prasad;Andrea Evenski;Audrey Baker.
Nature (2000)

430 Citations

Up-Regulation of Dicer, a Component of the MicroRNA Machinery, in Prostate Adenocarcinoma

Simion Chiosea;Elena Jelezcova;Uma Chandran;Marie Acquafondata.
American Journal of Pathology (2006)

405 Citations

Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells.

Paola Fortini;Barbara Pascucci;Eleonora Parlanti;Robert W. Sobol.
Biochemistry (1998)

326 Citations

Overexpression of Dicer in precursor lesions of lung adenocarcinoma.

Simion Chiosea;Elena Jelezcova;Uma Chandran;Jianhua Luo.
Cancer Research (2007)

299 Citations

Base Excision Repair and Lesion-Dependent Subpathways for Repair of Oxidative DNA Damage

David Svilar;Eva M. Goellner;Karen H. Almeida;Robert W. Sobol.
Antioxidants & Redox Signaling (2011)

272 Citations

The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death.

Ram N. Trivedi;Karen H. Almeida;Jamie L. Fornsaglio;Sandra Schamus.
Cancer Research (2005)

249 Citations

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