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D-Index & Metrics

Molecular Biology

D-Index
52
Citations
8741
World Ranking
2446
National Ranking
1206

Overview

Li Lan is affiliated with Duke University in the United States and has contributed extensively to research in the fields of biochemistry, genetics, molecular biology, and medicine. Their work prominently spans molecular biology, pulmonary and respiratory medicine, oncology, cancer research, and cardiovascular medicine.

The scientist's research concentrates on several interconnected areas, including DNA repair mechanisms, RNA modifications related to cancer, and genetic engineering techniques such as CRISPR. Additional focus areas include RNA research and splicing, mechanisms of RNA and protein synthesis, cancer-related molecular pathways, and peptidase inhibition and analysis.

Frequent coauthors collaborating with Li Lan include:

  • Lee Zou (13 joint publications)
  • Haibo Yang (12 joint publications)
  • Jian Ouyang (7 joint publications)
  • Xueping Zhu (5 joint publications)
  • Boya Gao (5 joint publications)

Li Lan has published numerous research articles in prominent scientific journals. Recurring publication venues are:

  • Nature Communications (5 publications)
  • Cancer Research (5 publications)
  • Research Square (3 publications)
  • Nature Reviews Molecular Cell Biology (2 publications)
  • Genes & Development (2 publications)

Notable recent papers authored or co-authored by Li Lan include:

  • "Sources, resolution and physiological relevance of R-loops and RNA-DNA hybrids," published in 2022 in Nature Reviews Molecular Cell Biology
  • "FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation," published in 2022 in Proceedings of the National Academy of Sciences
  • "m5C modification of mRNA serves a DNA damage code to promote homologous recombination," published in 2020 in Nature Communications
  • "DNA repair defects in cancer and therapeutic opportunities," published in 2022 in Genes & Development
  • "RNA transcripts stimulate homologous recombination by forming DR-loops," published in 2021 in Nature

Best Publications

  • ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors

    Jianfeng Shen;Yang Peng;Leizhen Wei;Wei Zhang

  • Spatial and temporal cellular responses to single-strand breaks in human cells.

    Satoshi Okano;Li Lan;Keith W. Caldecott;Toshio Mori

  • In situ analysis of repair processes for oxidative DNA damage in mammalian cells

    Li Lan;Satoshi Nakajima;Yoshitsugu Oohata;Masashi Takao

  • Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways.

    Jia-Min Zhang;Tribhuwan Yadav;Jian Ouyang;Li Lan

  • MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes

    Teresa M. Wilson;Alexandra Vaisman;Stella A. Martomo;Patsa Sullivan

  • Differential Phosphorylation of DNA-PKcs Regulates the Interplay between End-Processing and End-Ligation during Nonhomologous End-Joining

    Wenxia Jiang;Jennifer L. Crowe;Xiangyu Liu;Satoshi Nakajima

  • The ACF1 Complex Is Required for DNA Double-Strand Break Repair in Human Cells

    Li Lan;Ayako Ui;Ayako Ui;Satoshi Nakajima;Kotomi Hatakeyama

  • Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.

    Mengtan Xing;Mingrui Yang;Wei Huo;Feng Feng

  • A novel human AP endonuclease with conserved zinc‐finger‐like motifs involved in DNA strand break responses

    Shin Ichiro Kanno;Hiroyuki Kuzuoka;Shigeru Sasao;Zehui Hong

  • Vertebrate POLQ and POLβ cooperate in base excision repair of oxidative DNA damage

    Michio Yoshimura;Masaoki Kohzaki;Jun Nakamura;Kenjiro Asagoshi

  • DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

    Leizhen Wei;Satoshi Nakajima;Stefanie Böhm;Kara A. Bernstein

  • Accumulation of Werner protein at DNA double-strand breaks in human cells

    Li Lan;Satoshi Nakajima;Kenshi Komatsu;Andre Nussenzweig

  • Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.

    Dong Hu;Mert Gur;Zhuan Zhou;Armin Gamper

  • DNA Polymerase λ Protects Mouse Fibroblasts against Oxidative DNA Damage and Is Recruited to Sites of DNA Damage/Repair

    Elena K. Braithwaite;Padmini S. Kedar;Li Lan;Yaroslava Y. Polosina

  • ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB

    Yaqun Teng;Tribhuwan Yadav;Meihan Duan;Meihan Duan;Jun Tan

  • m5C modification of mRNA serves a DNA damage code to promote homologous recombination.

    Hao Chen;Haibo Yang;Xiaolan Zhu;Tribhuwan Yadav

  • HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

    Qingming Fang;Burcu Inanc;Sandy Schamus;Xiao-hong Wang

  • RNA transcripts stimulate homologous recombination by forming DR-loops.

    Jian Ouyang;Tribhuwan Yadav;Jia-Min Zhang;Haibo Yang

  • BLM is an early responder to DNA double-strand breaks.

    Parimal Karmakar;Masayuki Seki;Makoto Kanamori;Kazunari Hashiguchi

  • Recruitment of mismatch repair proteins to the site of DNA damage in human cells.

    Zehui Hong;Jie Jiang;Kazunari Hashiguchi;Mikiko Hoshi

Frequent Co-Authors

Zhiwei Lian
Zhiwei Lian Shanghai Jiao Tong University
Akira Yasui
Akira Yasui Tohoku University
Pawel Wargocki
Pawel Wargocki Technical University of Denmark
Lee Zou
Lee Zou Duke University
Bing Su
Bing Su Shanghai Jiao Tong University
Toshio Mori
Toshio Mori Nara Medical University
Kiyoji Tanaka
Kiyoji Tanaka University of Tsukuba
Robert W. Sobol
Robert W. Sobol University of South Alabama
Chikashi Ishioka
Chikashi Ishioka Tohoku University
Samuel H. Wilson
Samuel H. Wilson National Institutes of Health

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