Her primary areas of study are Biochemistry, DNA, DNA polymerase, Molecular biology and DNA repair. Her study in AP site, Tyrosyl-DNA Phosphodiesterase 1, DNA polymerase beta, DNA ligase and Polymerase falls under the purview of Biochemistry. Her Tyrosyl-DNA Phosphodiesterase 1 research includes elements of Stereochemistry and Cytotoxicity.
Her DNA polymerase study integrates concerns from other disciplines, such as DNA clamp, DNA polymerase I, DNA polymerase II, Primer and DNA replication. Her research combines Base excision repair and Molecular biology. Her research in DNA repair is mostly focused on Nucleotide excision repair.
Olga I. Lavrik spends much of her time researching Biochemistry, DNA, Molecular biology, DNA polymerase and DNA repair. Her research investigates the link between Biochemistry and topics such as Replication protein A that cross with problems in HMG-box and Protein subunit. Her work deals with themes such as Photoaffinity labeling, Biophysics and Cell biology, which intersect with DNA.
Her research integrates issues of Polymerase, Primase, DNA polymerase I, Primer and DNA synthesis in her study of DNA polymerase. Her research brings together the fields of DNA damage and DNA repair. The Base excision repair study combines topics in areas such as Proliferating cell nuclear antigen and AP site.
Olga I. Lavrik mostly deals with DNA, DNA repair, Biochemistry, Tyrosyl-DNA Phosphodiesterase 1 and Phosphodiesterase. In her study, Internalization and Double stranded is strongly linked to Cell biology, which falls under the umbrella field of DNA. Her DNA repair research incorporates elements of Transcription, DNA damage and DNA replication.
Her Tyrosyl-DNA Phosphodiesterase 1 study combines topics in areas such as Covalent bond, Stereochemistry and Topoisomerase-I Inhibitor. Her Phosphodiesterase research incorporates themes from Structure–activity relationship, Topoisomerase, Topotecan and Pharmacology. Her AP site research integrates issues from DNA glycosylase and DNA polymerase.
Olga I. Lavrik mainly focuses on DNA repair, DNA, Phosphodiesterase, Biochemistry and DNA damage. In general DNA repair, her work in Base excision repair is often linked to Naked mole-rat linking many areas of study. Her work carried out in the field of Base excision repair brings together such families of science as AP site, DNA polymerase and Protein–protein interaction.
As a part of the same scientific family, Olga I. Lavrik mostly works in the field of AP site, focusing on Molecular biology and, on occasion, Uracil and Nucleotide excision repair. DNA is closely attributed to Cell biology in her research. Her study looks at the relationship between Phosphodiesterase and topics such as Topoisomerase, which overlap with Topotecan.
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The crystal structure of phenylalanyl-tRNA synthetase from Thermus thermophilus complexed with cognate tRNAPhe
Yehuda Goldgur;Lidia Mosyak;Ludmila Reshetnikova;Valentina Ankilova.
Structure (1997)
DNA Polymerase β-mediated Long Patch Base Excision Repair POLY(ADP-RIBOSE) POLYMERASE-1 STIMULATES STRAND DISPLACEMENT DNA SYNTHESIS
Rajendra Prasad;Olga I. Lavrik;Soon-Jong Kim;Padmini Kedar.
Journal of Biological Chemistry (2001)
Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair.
Olga I. Lavrik;Olga I. Lavrik;Rajendra Prasad;Robert W. Sobol;Julie K. Horton.
Journal of Biological Chemistry (2001)
Human replication protein A unfolds telomeric G-quadruplexes.
Tonatiuh Romero Salas;Irina Petruseva;Olga Lavrik;Anne Bourdoncle.
Nucleic Acids Research (2006)
Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins.
Elizaveta E Alemasova;Olga I Lavrik.
Nucleic Acids Research (2019)
HMGB1 is a cofactor in mammalian base excision repair.
Rajendra Prasad;Yuan Liu;Leesa J. Deterding;Vladimir P. Poltoratsky.
Molecular Cell (2007)
Apurinic/apyrimidinic (AP) site recognition by the 5′-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)
S. N. Khodyreva;R. Prasad;E. S. Ilina;M. V. Sukhanova.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase β and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity
Maria V. Sukhanova;Svetlana N. Khodyreva;Natalia A. Lebedeva;Rajendra Prasad.
Nucleic Acids Research (2005)
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1.
Natalia A. Lebedeva;Nadejda I. Rechkunova;Olga I. Lavrik.
FEBS Letters (2011)
Polarity of human replication protein A binding to DNA
Dmitry M. Kolpashchikov;Svetlana N. Khodyreva;Denis Yu. Khlimankov;Marc S. Wold.
Nucleic Acids Research (2001)
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