D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 118 Citations 44,883 463 World Ranking 217 National Ranking 131

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are DNA repair, Molecular biology, DNA damage, DNA and Mitochondrion. His research in DNA repair intersects with topics in Mitochondrial DNA and Cell biology. His work carried out in the field of Cell biology brings together such families of science as Mitophagy and NAD+ kinase.

His Molecular biology research is multidisciplinary, incorporating perspectives in Base excision repair, DNA glycosylase, DNA mismatch repair, Nucleotide excision repair and Gene. In his research, Mutagenesis is intimately related to Oxidative stress, which falls under the overarching field of DNA damage. He interconnects Autophagy, Neurodegeneration and Neuroscience in the investigation of issues within Mitochondrion.

His most cited work include:

  • SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin (776 citations)
  • Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival (731 citations)
  • Metformin improves healthspan and lifespan in mice (683 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in DNA repair, Molecular biology, DNA damage, DNA and Cell biology. His study in the field of Nucleotide excision repair and Base excision repair is also linked to topics like Premature aging. The concepts of his Molecular biology study are interwoven with issues in Cell culture, Chinese hamster ovary cell, AP site, Pyrimidine dimer and Gene.

His DNA damage research incorporates elements of Oxidative stress, Cancer research, Poly ADP ribose polymerase and Senescence. His Cell biology study incorporates themes from Neurodegeneration and NAD+ kinase. His Mitochondrial DNA research integrates issues from Mitochondrial DNA repair and Mitochondrion.

He most often published in these fields:

  • DNA repair (63.73%)
  • Molecular biology (41.86%)
  • DNA damage (39.32%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (33.05%)
  • DNA repair (63.73%)
  • Mitochondrion (23.56%)

In recent papers he was focusing on the following fields of study:

Vilhelm A. Bohr mainly investigates Cell biology, DNA repair, Mitochondrion, DNA damage and Mitophagy. His study in Cell biology is interdisciplinary in nature, drawing from both Biochemistry, DNA, Neurodegeneration, Werner syndrome and NAD+ kinase. His work on Base excision repair and Nucleotide excision repair as part of general DNA repair study is frequently linked to Premature aging, therefore connecting diverse disciplines of science.

In his study, Oxidative phosphorylation is strongly linked to Oxidative stress, which falls under the umbrella field of Mitochondrion. The study incorporates disciplines such as Cancer research, Molecular biology, Poly ADP ribose polymerase, Gene and Nuclear DNA in addition to DNA damage. His Mitophagy research includes elements of Caenorhabditis elegans, Genome instability and Disease.

Between 2014 and 2021, his most popular works were:

  • Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease (310 citations)
  • Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease (310 citations)
  • Ageing as a risk factor for neurodegenerative disease. (261 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary scientific interests are in Cell biology, DNA repair, Mitophagy, Mitochondrion and DNA damage. His work carried out in the field of Cell biology brings together such families of science as Homologous recombination, Exonuclease, Werner syndrome, Telomere and NAD+ kinase. His research integrates issues of Genome instability and Mitochondrial DNA in his study of DNA repair.

His Mitophagy study combines topics from a wide range of disciplines, such as Disease and Caenorhabditis elegans. His research in DNA damage intersects with topics in Apoptosis, Nicotinamide riboside, Gene, SIRT3 and Nuclear DNA. His DNA research is multidisciplinary, relying on both Protein structure, Molecular biology and Nucleic acid secondary structure.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Eriko Michishita;Ronald A. McCord;Elisabeth Berber;Mitomu Kioi.
Nature (2008)

1027 Citations

Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

Hongying Yang;Tianle Yang;Joseph A. Baur;Evelyn Perez.
Cell (2007)

937 Citations

Metformin improves healthspan and lifespan in mice

Alejandro Martin-Montalvo;Evi M. Mercken;Sarah J. Mitchell;Sarah J. Mitchell;Sarah J. Mitchell;Hector H. Palacios.
Nature Communications (2013)

915 Citations

p53 modulation of TFIIH-associated nucleotide excision repair activity.

Xin Wei Wang;H. Yeh;L. Schaeffer;Richard Roy.
Nature Genetics (1995)

683 Citations

REPAIR OF OXIDATIVE DAMAGE TO NUCLEAR AND MITOCHONDRIAL DNA IN MAMMALIAN CELLS

Deborah L. Croteau;Vilhelm A. Bohr.
Journal of Biological Chemistry (1997)

678 Citations

Base excision repair of oxidative DNA damage and association with cancer and aging.

Scott Maynard;Shepherd H. Schurman;Charlotte Harboe;Nadja C. de Souza-Pinto.
Carcinogenesis (2008)

631 Citations

Preferential DNA repair of an active gene in human cells

Isabel Mellon;Vilhelm A. Bohr;Charles Allen Smith;Philip C. Hanawalt.
Proceedings of the National Academy of Sciences of the United States of America (1986)

567 Citations

Telomere-binding Protein TRF2 Binds to and Stimulates the Werner and Bloom Syndrome Helicases

Patricia L. Opresko;Cayetano von Kobbe;Jean-Philippe Laine;Jean-Philippe Laine;Jeanine Harrigan.
Journal of Biological Chemistry (2002)

512 Citations

Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells.

Vilhelm A Bohr.
Free Radical Biology and Medicine (2002)

485 Citations

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.

Angelos Constantinou;Madalena Tarsounas;Julia K Karow;Robert M Brosh.
EMBO Reports (2000)

448 Citations

Best Scientists Citing Vilhelm A. Bohr

Mark P. Mattson

Mark P. Mattson

Johns Hopkins University School of Medicine

Publications: 88

Philip C. Hanawalt

Philip C. Hanawalt

Stanford University

Publications: 79

Robert M. Brosh

Robert M. Brosh

National Institutes of Health

Publications: 74

David A. Sinclair

David A. Sinclair

Harvard University

Publications: 72

Rafael de Cabo

Rafael de Cabo

National Institutes of Health

Publications: 67

Sankar Mitra

Sankar Mitra

Houston Methodist

Publications: 65

Jan H.J. Hoeijmakers

Jan H.J. Hoeijmakers

Erasmus University Rotterdam

Publications: 62

Ian D. Hickson

Ian D. Hickson

University of Copenhagen

Publications: 58

Magnar Bjørås

Magnar Bjørås

Norwegian University of Science and Technology

Publications: 54

Glenn L. Wilson

Glenn L. Wilson

University of South Alabama

Publications: 53

Kaare Christensen

Kaare Christensen

University of Southern Denmark

Publications: 52

David M. Wilson

David M. Wilson

Hasselt University

Publications: 50

Curtis C. Harris

Curtis C. Harris

National Institutes of Health

Publications: 48

Miral Dizdaroglu

Miral Dizdaroglu

National Institute of Standards and Technology

Publications: 46

Samuel H. Wilson

Samuel H. Wilson

National Institutes of Health

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Olga I. Lavrik

Olga I. Lavrik

Russian Academy of Sciences

Publications: 43

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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