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Molecular Biology

D-Index
90
Citations
26209
World Ranking
742
National Ranking
400

Research.com Recognitions

  • 1989 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Sankar Mitra is affiliated with Houston Methodist in the United States. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. The subfields reflecting their focus include Molecular Biology, Neurology, Pulmonary and Respiratory Medicine, Genetics, and Oncology.

The core topics of their scientific work include DNA Repair Mechanisms, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, Amyotrophic Lateral Sclerosis Research, PARP inhibition in cancer therapy, DNA and Nucleic Acid Chemistry, and Radiation Therapy and Dosimetry.

Sankar Mitra's recent publications cover a range of research areas. Selected papers include:

  • "Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle" (2020), ACS Nano
  • "XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells" (2020), NAR Cancer
  • "Protein Adsorption on Biomaterial Surfaces: Subsequent Conformational and Biological Consequences - A Review" (2020), Journal of Surface Science and Technology
  • "Transcription coupled base excision repair in mammalian cells: So little is known and so much to uncover" (2021), DNA Repair
  • "Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin" (2020), Nucleic Acids Research

Their work has been published in venues including DNA Repair, ACS Nano, Journal of Surface Science and Technology, Nature Communications, and NAR Cancer.

Frequent collaborators in their research efforts include:

  • Muralidhar L. Hegde
  • Joy Mitra
  • Pavana M. Hegde
  • Albino Bacolla
  • John A. Tainer

Their contributions intersect molecular biology and clinical research, reflecting a multidisciplinary approach to understanding disease mechanisms and therapeutic potentials.

Sankar Mitra received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 1989.

Best Publications

  • Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

    Asima Bhattacharyya;Asima Bhattacharyya;Asima Bhattacharyya;Ranajoy Chattopadhyay;Ranajoy Chattopadhyay;Ranajoy Chattopadhyay;Sankar Mitra;Sheila E. Crowe;Sheila E. Crowe;Sheila E. Crowe

  • DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination

    Clifford D. Mol;Tadahide Izumi;Sankar Mitra;John A. Tainer

  • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells.

    Muralidhar L Hegde;Tapas K Hazra;Sankar Mitra

  • Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.

    Tapas K. Hazra;Tadahide Izumi;Istvan Boldogh;Barry Imhoff

  • AP endonuclease-independent DNA base excision repair in human cells

    Lee R Wiederhold;John B. Leppard;Padmini Kedar;Feridoun Karimi-Busheri

  • Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals.

    Chilakamarti V. Ramana;Istvan Boldogh;Tadahide Izumi;Sankar Mitra

  • Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair

    Jeff W. Hill;Tapas K. Hazra;Tadahide Izumi;Sankar Mitra

  • ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation

    Istvan Boldogh;Attila Bacsi;Barun K. Choudhury;Nilesh Dharajiya

  • Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2.

    Hong Dou;Sankar Mitra;Tapas K. Hazra

  • Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine

    Keizo Tano;Susumu Shiota;Julia Collier;Robert S. Foote

  • Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions.

    Tapas K. Hazra;Yoke W. Kow;Zafar Hatahet;Barry Imhoff

  • Purification and Characterization of Human NTH1, a Homolog of Escherichia coli Endonuclease III

    Shogo Ikeda;Tapan Biswas;Rabindra Roy;Tadahide Izumi

  • Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.

    Bernd Kaina;Gerhard Fritz;Sankar Mitra;Thérèse Coquerelle

  • Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein

    Kishor K. Bhakat;Anil K. Mantha;Sankar Mitra

  • Two essential but distinct functions of the mammalian abasic endonuclease.

    Tadahide Izumi;Tadahide Izumi;David B. Brown;C. V. Naidu;C. V. Naidu;Kishor K. Bhakat

  • Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage

    Tadahide Izumi;Lee R. Wiederhold;Gargi Roy;Rabindra Roy

  • Purification and properties of O6-methylguanine-DNA transmethylase from rat liver.

    A. E. Pegg;L. Wiest;R. S. Foote;Sankar Mitra

  • Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.

    Joy Mitra;Erika N. Guerrero;Erika N. Guerrero;Pavana M. Hegde;Nicole F. Liachko

  • erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination

    Clifford D. Mol;Tadahide Izumi;Sankar Mitra;John A. Tainer

  • Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

    Robert E. Johnson;Carlos A. Torres-Ramos;Tadahide Izumi;Sankar Mitra

Frequent Co-Authors

Tapas K. Hazra
Tapas K. Hazra The University of Texas Medical Branch at Galveston
Istvan Boldogh
Istvan Boldogh The University of Texas Medical Branch at Galveston
Sheila E. Crowe
Sheila E. Crowe University of California, San Diego
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Alan E. Tomkinson
Alan E. Tomkinson University of New Mexico
Darell D. Bigner
Darell D. Bigner Duke University
Bernd Kaina
Bernd Kaina Johannes Gutenberg University of Mainz
John Papaconstantinou
John Papaconstantinou The University of Texas Medical Branch at Galveston
Peter B. Ernst
Peter B. Ernst University of California, San Diego
Naomi J. Halas
Naomi J. Halas Rice University

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