World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
99
Citations
32031
World Ranking
557
National Ranking
49

Overview

Bernd Kaina is affiliated with Johannes Gutenberg University of Mainz in Germany and has made contributions primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research subfields include Molecular Biology, Oncology, Genetics, Surgery, and Cancer Research.

The scientist's work covers multiple research topics, notably:

  • Glioma Diagnosis and Treatment
  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Brain Metastases and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Effects of Radiation Exposure
  • Cancer, Hypoxia, and Metabolism

Bernd Kaina has published extensively, with notable recent papers including:

  • "Comparison of DNA repair and radiosensitivity of different blood cell populations," 2021, Scientific Reports
  • "Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells," 2022, Cancers
  • "Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence," 2020, Nucleic Acids Research
  • "Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo," 2021, Archives of Toxicology
  • "Cytotoxic, Genotoxic and Senolytic Potential of Native and Micellar Curcumin," 2021, Nutrients

Frequent co-authors in the scientist's publications include:

  • Lea Beltzig
  • Markus Christmann
  • Jörg Fahrer
  • Christian Schwarzenbach
  • Thomas Kindler

Bernd Kaina's publications appear in a variety of venues, with multiple papers in:

  • WFNOS 2022 Abstract Book
  • Cancers
  • Zeitschrift für Gastroenterologie
  • International Journal of Molecular Sciences
  • Book of Abstracts

Best Publications

  • Rho GTPases are over‐expressed in human tumors

    Gerhard Fritz;Ingo Just;Bernd Kaina

  • From traditional Chinese medicine to rational cancer therapy

    Thomas Efferth;Paul C.H. Li;Venkata S. Badireenath Konkimalla;Bernd Kaina

  • Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

    W. P. Roos;L. F.Z. Batista;S. C. Naumann;Wolfgang Wick

  • Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters.

    G Fritz;C Brachetti;F Bahlmann;M Schmidt

  • Cisplatin resistance: preclinical findings and clinical implications.

    Beate Köberle;Maja T. Tomicic;Svetlana Usanova;Bernd Kaina

  • O6‐methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

    Mirjam Hermisson;Andrea Klumpp;Wolfgang Wick;Jörg Wischhusen

  • DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling

    Bernd Kaina

  • Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron.

    Thomas Efferth;Achille Benakis;Marta R. Romero;Maja Tomicic

  • Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent.

    Kirsten Ochs;Bernd Kaina

  • Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.

    Bernd Kaina;Gerhard Fritz;Sankar Mitra;Thérèse Coquerelle

  • The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth.

    Cornelia Dietrich;Bernd Kaina

  • How DNA lesions are turned into powerful killing structures: insights from UV-induced apoptosis.

    Luís F.Z. Batista;Bernd Kaina;Rogério Meneghini;Carlos F.M. Menck

  • Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation.

    Markus Christmann;Bernd Kaina

  • O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry.

    Markus Christmann;Barbara Verbeek;Wynand P. Roos;Bernd Kaina

  • Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage.

    Anna V. Knizhnik;Wynand P. Roos;Teodora Nikolova;Steve Quiros

  • Toxicity of the antimalarial artemisinin and its dervatives

    Thomas Efferth;Bernd Kaina

  • Rho GTPases: promising cellular targets for novel anticancer drugs.

    Gerhard Fritz;Bernd Kaina

  • Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.

    Bernd Kaina;Aliki Ziouta;Kirsten Ochs;Therese Coquerelle

  • Variability and regulation of O6-alkylguanine–DNA alkyltransferase

    Geoffrey P. Margison;Andrew C. Povey;Bernd Kaina;Mauro F. Santibáñez Koref

  • Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

    Paul C.H. Li;Elena Lam;Wynand P. Roos;Małgorzata Z. Zdzienicka

Frequent Co-Authors

Gerhard Fritz
Gerhard Fritz Johannes Gutenberg University of Mainz
Thomas Efferth
Thomas Efferth Johannes Gutenberg University of Mainz
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University
Sankar Mitra
Sankar Mitra Houston Methodist
Bernd Epe
Bernd Epe Johannes Gutenberg University of Mainz
Franz Oesch
Franz Oesch Johannes Gutenberg University of Mainz
Peter Wutzler
Peter Wutzler Friedrich Schiller University Jena
Ari Waisman
Ari Waisman Johannes Gutenberg University of Mainz
Frank Rösch
Frank Rösch Johannes Gutenberg University of Mainz
Peter Herrlich
Peter Herrlich Leibniz Association

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Molecular Biology, alternative or complementary online degree options may be worth considering. Many professionals in healthcare fields begin with nursing and later explore related scientific disciplines. If you’re looking to advance your nursing qualifications, it’s helpful to compare capella rn to bsn vs chamberlain rn to bsn for online RN to BSN programs. These programs help working nurses boost their credentials with flexible, online formats.

For those aiming to pursue leadership or specialized clinical roles, there are a range of bsn to msn programs online that offer advanced training and career development in the nursing field. Convenience and affordability are often top priorities for adult learners, so it’s wise to focus on reputable, non profit colleges recognized for their accredited online degrees.

Additionally, students with military backgrounds or commitments can benefit from researching military friendly colleges that provide tailored support and flexible scheduling. Exploring these pathways can help you find the online program that best matches your academic goals and personal needs.

Best Scientists Citing Bernd Kaina

Trending Scientists