D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 111 Citations 50,546 579 World Ranking 645 National Ranking 430

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

The scientist’s investigation covers issues in Biochemistry, Molecular biology, Polyamine, Spermidine and Alkyltransferase. DNA, Enzyme, Ornithine decarboxylase, Carcinogen and Ornithine decarboxylase antizyme are among the areas of Biochemistry where the researcher is concentrating his efforts. His research on Molecular biology also deals with topics like

  • Carcinogenesis, which have a strong connection to Mutagenesis,
  • Cell culture that connect with fields like Cytotoxic T cell and Cytotoxicity.

His studies in Polyamine integrate themes in fields like Polyamine homeostasis, Polyamine transport, Polyamine Analogue, Polyamine Catabolism and Spermine oxidase. His Spermidine research is multidisciplinary, relying on both Putrescine, Acetylation, Cellular differentiation and Spermine. His work deals with themes such as O6-Benzylguanine, Glioma, O-6-methylguanine-DNA methyltransferase and DNA repair, which intersect with Alkyltransferase.

His most cited work include:

  • Polyamine Metabolism and Its Importance in Neoplastic Growth and as a Target for Chemotherapy (1444 citations)
  • Recent advances in the biochemistry of polyamines in eukaryotes. (1408 citations)
  • Polyamine metabolism and function. (1265 citations)

What are the main themes of his work throughout his whole career to date?

Anthony E. Pegg mainly focuses on Biochemistry, Molecular biology, Spermidine, Polyamine and Spermine. Enzyme, DNA, Alkyltransferase, Ornithine decarboxylase and Guanine are among the areas of Biochemistry where he concentrates his study. His research investigates the connection between Alkyltransferase and topics such as O6-Benzylguanine that intersect with problems in Nitrosourea.

His studies deal with areas such as Cell culture, Transfection, Methylation, Carcinogenesis and In vivo as well as Molecular biology. The various areas that Anthony E. Pegg examines in his Spermidine study include Acetyltransferase, Putrescine, Endocrinology and Internal medicine. His work carried out in the field of Polyamine brings together such families of science as Polyamine transport, Methylglyoxal, Cell growth, Polyamine Analogue and Intracellular.

He most often published in these fields:

  • Biochemistry (69.87%)
  • Molecular biology (38.76%)
  • Spermidine (32.41%)

What were the highlights of his more recent work (between 2005-2018)?

  • Biochemistry (69.87%)
  • Polyamine (26.55%)
  • Spermidine (32.41%)

In recent papers he was focusing on the following fields of study:

Anthony E. Pegg focuses on Biochemistry, Polyamine, Spermidine, Spermine and Alkyltransferase. Many of his studies on Biochemistry involve topics that are commonly interrelated, such as Stereochemistry. Anthony E. Pegg has researched Polyamine in several fields, including Polyamine homeostasis, Endocrinology, Internal medicine, Polyamine Catabolism and Ornithine decarboxylase.

Anthony E. Pegg combines subjects such as Putrescine, Hypusine and Transgene with his study of Spermidine. His Alkyltransferase research incorporates themes from Duplex, O-6-methylguanine-DNA methyltransferase, Mutant and Cancer research. His DNA study combines topics in areas such as Molecular biology, Carcinogen, Guanine and Recombinant DNA.

Between 2005 and 2018, his most popular works were:

  • Mammalian polyamine metabolism and function (466 citations)
  • Regulation of Ornithine Decarboxylase (347 citations)
  • Polyamine catabolism and disease. (262 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Anthony E. Pegg spends much of his time researching Biochemistry, Polyamine, Spermidine, Spermine and Spermine synthase. His Polyamine study combines topics from a wide range of disciplines, such as Polyamine homeostasis, Cancer, Protein biosynthesis, Polyamine Catabolism and Cell biology. In his study, Ornithine decarboxylase antizyme and Ornithine decarboxylase is inextricably linked to Neuroblastoma, which falls within the broad field of Cancer.

His Spermidine research includes themes of Putrescine, Reactive oxygen species, Transferase and Oxidase test. He focuses mostly in the field of Spermine, narrowing it down to topics relating to Cell damage and, in certain cases, Toxicity, Oxidative phosphorylation and Catabolism. In DNA repair, Anthony E. Pegg works on issues like O-6-methylguanine-DNA methyltransferase, which are connected to Alkyltransferase, DNA Repair Protein, Guanine and Nucleotide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Recent advances in the biochemistry of polyamines in eukaryotes.

A E Pegg.
Biochemical Journal (1986)

2296 Citations

Polyamine Metabolism and Its Importance in Neoplastic Growth and as a Target for Chemotherapy

Anthony E. Pegg.
Cancer Research (1988)

2281 Citations

Polyamine metabolism and function.

A. E. Pegg;P. P. McCann.
American Journal of Physiology-cell Physiology (1982)

2022 Citations

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents.

Anthony E. Pegg.
Cancer Research (1990)

1078 Citations

Polyamines as Targets for Therapeutic Intervention

L J Marton;A E Pegg.
Annual Review of Pharmacology and Toxicology (1995)

931 Citations

Repair of O6-alkylguanine by alkyltransferases

Anthony E Pegg.
Mutation Research-reviews in Mutation Research (2000)

753 Citations

Mammalian polyamine metabolism and function

Anthony E. Pegg.
Iubmb Life (2009)

714 Citations

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

M E Dolan;R C Moschel;A E Pegg.
Proceedings of the National Academy of Sciences of the United States of America (1990)

612 Citations

Structure, function, and inhibition of O6-alkylguanine-DNA alkyltransferase.

Anthony E. Pegg;M. Eileen Dolan;Robert C. Moschel.
Progress in Nucleic Acid Research and Molecular Biology (1995)

603 Citations

Spermidine/spermine N1-acetyltransferase--the turning point in polyamine metabolism.

Robert A. Casero;Anthony E. Pegg.
The FASEB Journal (1993)

550 Citations

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