World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
67
Citations
11150
World Ranking
2945
National Ranking
1362

Overview

Wulf Paschen is affiliated with Duke University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular attention to molecular biology, cell biology, cellular and molecular neuroscience, physiology, and immunology.

The scientist's work spans multiple key topics including:

  • Endoplasmic Reticulum Stress and Disease
  • RNA regulation and disease
  • Nerve injury and regeneration
  • Glycosylation and Glycoproteins Research
  • Lysosomal Storage Disorders Research
  • Galectins and Cancer Biology
  • Ubiquitin and proteasome pathways

Paschen has contributed research papers published in several notable scientific journals. Selected recent papers include:

  • "PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis," 2020, Stroke
  • "Increasing O-GlcNAcylation is neuroprotective in young and aged brains after ischemic stroke," 2021, Experimental Neurology
  • "Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice," 2020, The FASEB Journal

Their frequent co-authors include:

  • Yuntian Shen
  • Huaxin Sheng
  • Wei Yang
  • Xuan Li
  • Jingjun Lyu

Paschen has published work primarily in the following venues:

  • Stroke
  • Experimental Neurology
  • The FASEB Journal

The scientist's research integrates molecular mechanisms underlying neuroprotection and memory, with a particular focus on cellular stress responses such as unfolded protein response pathways and post-translational protein modifications. Their studies also explore the biological roles of glycosylation dynamics and ubiquitin-related processes, relevant to disease models including ischemic stroke and neurodegeneration.

Best Publications

  • Endoplasmic reticulum stress response and neurodegeneration.

    Wulf Paschen;Thorsten Mengesdorf

  • Endoplasmic reticulum dysfunction: a common denominator for cell injury in acute and degenerative diseases of the brain?

    Wulf Paschen;Aase Frandsen

  • Disturbances of the Functioning of Endoplasmic Reticulum: A Key Mechanism Underlying Neuronal Cell Injury?

    Wulf Paschen;Jens Doutheil

  • Endoplasmic reticulum stress.

    Gábor Bánhegyi;Peter Baumeister;Angelo Benedetti;Dezheng Dong

  • Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain.

    Wulf Paschen

  • Lactate and pH in the brain: association and dissociation in different pathophysiological states.

    W. Paschen;B. Djuricic;G. Mies;R. Schmidt-Kastner

  • SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development

    Liangli Wang;Carolien Wansleeben;Shengli Zhao;Pei Miao

  • Regional changes of blood flow, glucose, and ATP content determined on brain sections during a single passage of spreading depression in rat brain cortex.

    G. Mies;W. Paschen

  • Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states.

    W. Paschen

  • Transient Global Cerebral Ischemia Induces a Massive Increase in Protein Sumoylation

    Wei Yang;Huaxin Sheng;David S Warner;Wulf Paschen

  • A modified four-vessel occlusion model for inducing incomplete forebrain ischemia in rats.

    R Schmidt-Kastner;W Paschen;B G Ophoff;K A Hossmann

  • Relationship between Calcium Accumulation and Recovery of Cat Brain after Prolonged Cerebral Ischemia

    K.-A. Hossmann;W. Paschen;L. Csiba

  • Transient Cerebral Ischemia Activates Processing of xbp1 Messenger RNA Indicative of Endoplasmic Reticulum Stress

    Wulf Paschen;Christoph Aufenberg;Svenja Hotop;Thorsten Mengesdorf

  • Polyamine changes in reversible cerebral ischemia.

    W. Paschen;R. Schmidt-Kastner;B. Djuricic;C. Meese

  • Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction.

    Wulf Paschen;Cornelia Gissel;Thomas Linden;Sonja Althausen

  • SUMO2/3 Conjugation is an Endogenous Neuroprotective Mechanism:

    Anna Lena Datwyler;Gisela Lättig-Tünnemann;Wei Yang;Wulf Paschen;Wulf Paschen

  • Changes in the phosphorylation of initiation factor eIF‐2α, elongation factor eEF‐2 and p70 S6 kinase after transient focal cerebral ischaemia in mice

    Sonja Althausen;Thorsten Mengesdorf;Günter Mies;Laszlo Oláh

  • Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage

    W. Paschen

  • Shutdown of Translation: Lethal or Protective? Unfolded Protein Response versus Apoptosis:

    Wulf Paschen

  • A bioluminescence method for the demonstration of regional glucose distribution in brain slices.

    W. Paschen;I. Niebuhr;K.-A. Hossmann

Frequent Co-Authors

William C. Wetsel
William C. Wetsel Duke University
Ramona M. Rodriguiz
Ramona M. Rodriguiz Duke University
Bo K. Siesjö
Bo K. Siesjö Lund University
Thomas Sander
Thomas Sander University of Cologne
Dennis A. Turner
Dennis A. Turner Duke University
Ulrich Dirnagl
Ulrich Dirnagl Charité - University Medicine Berlin
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Thomas F. Wienker
Thomas F. Wienker Max Planck Society
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen
Bettina Schmitz
Bettina Schmitz Charité - University Medicine Berlin

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in Neuroscience, you might also consider related online degrees that expand your skills and open up diverse career paths in mental health and counseling. Many students pursue advanced studies in areas such as counseling, psychology, or marriage and family therapy to complement their neuroscience background.

Accreditation and affordability are key concerns when selecting a program. Accredited institutions, such as cacrep schools, ensure that your education meets high professional standards, which is essential if you plan to seek licensure. There are also highly ranked programs in online clinical mental health counseling for those wanting to specialize in therapy and client care.

For those passionate about helping families and couples, consider a marriage and family therapy degree online. Additionally, advancing your expertise with a masters in psychology online can boost your credentials and unlock more career opportunities in clinical, academic, and research settings.

These online degrees offer flexibility and affordability, making them strong options for anyone interested in a dynamic career at the intersection of neuroscience, psychology, and counseling.

Best Scientists Citing Wulf Paschen

Trending Scientists

Recently Published Articles