What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His scientific interests lie mostly in Endocrinology, Internal medicine, Neuroscience, Cell biology and Pharmacology.
In the subject of general Internal medicine, his work in Hypothalamus, Open field and Systemic inflammation is often linked to Cartilage metabolism, thereby combining diverse domains of study.
His Neuroscience research is multidisciplinary, relying on both Synaptic plasticity and Neurotransmission.
As a part of the same scientific family, William C. Wetsel mostly works in the field of Cell biology, focusing on Synaptic vesicle and, on occasion, Transporter, Central nervous system and Acetylcholine.
The Pharmacology study combines topics in areas such as Dopamine receptor D2, Dopaminergic, Dopamine, Partial agonist and Computational biology.
His work carried out in the field of Dopaminergic brings together such families of science as Striatum, Norepinephrine, Knockout mouse, Serotonergic and Norepinephrine Plasma Membrane Transport Proteins.
His most cited work include:
- Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. (761 citations)
- Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3 -mutant mice (562 citations)
- Automated design of ligands to polypharmacological profiles (475 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Endocrinology, Internal medicine, Neuroscience, Pharmacology and Cell biology.
William C. Wetsel interconnects Receptor and Protein kinase C in the investigation of issues within Endocrinology.
His Internal medicine study frequently draws connections to other fields, such as Cell culture.
His studies link Synaptic plasticity with Neuroscience.
His research integrates issues of Agonist, Haloperidol, Dopamine receptor D2, Sensitization and Dopamine receptor in his study of Pharmacology.
His Hippocampus study combines topics in areas such as Hippocampal formation, Neuroplasticity and Knockout mouse.
He most often published in these fields:
- Endocrinology (36.52%)
- Internal medicine (36.52%)
- Neuroscience (30.00%)
What were the highlights of his more recent work (between 2016-2021)?
- Neuroscience (30.00%)
- Pharmacology (13.91%)
- Cell biology (12.61%)
In recent papers he was focusing on the following fields of study:
William C. Wetsel mostly deals with Neuroscience, Pharmacology, Cell biology, Hippocampus and Cognition.
His work deals with themes such as Synaptic plasticity, Schizophrenia and Lithium, which intersect with Neuroscience.
His study in Pharmacology is interdisciplinary in nature, drawing from both Psychosis, Prepulse inhibition, Dopamine and Dopamine receptor antagonist.
His Cell biology research includes elements of Knockout mouse, Functional morphology and Neurotransmitter.
William C. Wetsel combines subjects such as Phenotype, Genetics, Neuroinflammation and Delirium with his study of Hippocampus.
The research on Endocrinology and Internal medicine is part of his Ventral tegmental area project.
Between 2016 and 2021, his most popular works were:
- Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice (39 citations)
- Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. (37 citations)
- ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity (29 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
William C. Wetsel mainly focuses on Neuroscience, Dopamine, Pharmacology, Cognitive decline and Inhibitory postsynaptic potential.
William C. Wetsel has researched Neuroscience in several fields, including Agonist, Schizophrenia and Allosteric regulation.
His research in Dopamine intersects with topics in Neurodegeneration and Parkinson's disease.
His Pharmacology research includes themes of Alternating hemiplegia of childhood, Epilepsy, Kindling, Pathophysiology and Dystonia.
His Cognitive decline study combines topics from a wide range of disciplines, such as Inflammation, Neuropathology and Perioperative.
The study incorporates disciplines such as Nociception, Fear processing in the brain, Ca2+/calmodulin-dependent protein kinase and Amygdala in addition to Inhibitory postsynaptic potential.
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