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Biology and Biochemistry

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139
Citations
63412
World Ranking
285
National Ranking
193

Medicine

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138
Citations
63490
World Ranking
1842
National Ranking
1050

Research.com Recognitions

  • 2007 - Fellow of the American Society of Mechanical Engineers
  • 2005 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Farshid Guilak is affiliated with Washington University in St. Louis in the United States. Their research focuses primarily on the biomedical fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable subfields including Molecular Biology, Rheumatology, Physiology, Surgery, and Genetics. This multidisciplinary background supports a broad investigation into osteoarthritis and related biological processes.

The main topics that characterize Guilak's work include:

  • Osteoarthritis Treatment and Mechanisms
  • Erythrocyte Function and Pathophysiology
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Exercise and Physiological Responses
  • Knee Injuries and Reconstruction Techniques
  • Blood Properties and Coagulation

Their research output is published in a variety of venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Osteoarthritis and Cartilage
  • UNC Libraries
  • Science Advances
  • The FASEB Journal

Some of the recent papers authored or co-authored by Guilak include:

  • "The role of macrophages in osteoarthritis and cartilage repair," 2020, Osteoarthritis and Cartilage
  • "Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis," 2021, Proceedings of the National Academy of Sciences
  • "Adipose tissue is a critical regulator of osteoarthritis," 2020, Proceedings of the National Academy of Sciences
  • "Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis," 2021, Nature Communications
  • "A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues," 2021, Science Advances

Frequent collaborators of Guilak include:

  • Kelsey H. Collins
  • Alireza Savadipour
  • Ruhang Tang
  • Chia-Lung Wu
  • Natalia S. Harasymowicz

Within the scientific community, Guilak has been recognized as a Fellow of the American Society of Mechanical Engineers since 2007 and as a Fellow of the Indian National Academy of Engineering since 2005.

Best Publications

  • Control of stem cell fate by physical interactions with the extracellular matrix.

    Farshid Guilak;Daniel M. Cohen;Bradley T. Estes;Jeffrey M. Gimble

  • RNA-guided gene activation by CRISPR-Cas9-based transcription factors

    Pablo Perez-Pinera;D Dewran Kocak;Christopher M Vockley;Andrew F Adler

  • Adipose-derived adult stem cells: isolation, characterization, and differentiation potential

    J.M. Gimble;F. Guilak

  • Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds.

    Hani A. Awad;M. Quinn Wickham;Holly A. Leddy;Jeffrey M. Gimble

  • 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

    Sungmin Hong;Dalton Sycks;Hon Fai Chan;Shaoting Lin;Shaoting Lin

  • Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo.

    Geoffrey R. Erickson;Jeffrey M. Gimble;Dawn M. Franklin;Henry E. Rice

  • A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage

    Franklin T. Moutos;Lisa E. Freed;Farshid Guilak

  • Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells

    Evelyn K.F. Yim;Eric M. Darling;Karina Kulangara;Farshid Guilak

  • Functional Tissue Engineering: The Role of Biomechanics

    David L. Butler;Steven A. Goldstein;Farshid Guilak

  • POST-TRAUMATIC OSTEOARTHRITIS: IMPROVED UNDERSTANDING AND OPPORTUNITIES FOR EARLY INTERVENTION

    Donald D. Anderson;Susan Chubinskaya;Farshid Guilak;James A. Martin

  • Viscoelastic properties of the cell nucleus.

    Farshid Guilak;John R. Tedrow;Rainer Burgkart;Rainer Burgkart

  • Clonal analysis of the differentiation potential of human adipose-derived adult stem cells

    Farshid Guilak;Kristen E. Lott;Hani A. Awad;Qiongfang Cao

  • The mechanical environment of the chondrocyte: a biphasic finite element model of cell–matrix interactions in articular cartilage

    Farshid Guilak;Van C. Mow

  • Chondrocyte deformation and local tissue strain in articular cartilage: a confocal microscopy study.

    Farshid Guilak;Anthony Ratcliffe;Van C. Mow

  • Biomechanical factors in osteoarthritis.

    Farshid Guilak

  • Multipotent stromal cells derived from the infrapatellar fat pad of the knee.

    M Quinn Wickham;Geoffrey R Erickson;Jeffrey M Gimble;T Parker Vail

  • The role of mechanical loading in the onset and progression of osteoarthritis.

    Timothy M Griffin;Farshid Guilak

  • Compression-induced changes in the shape and volume of the chondrocyte nucleus

    Farshid Guilak

  • Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration.

    Michelle A. LeRoux;Farshid Guilak;Lori A. Setton

  • Isolation of adipose derived stem cells and their induction to a chondrogenic phenotype

    Bradley T Estes;Brian O Diekman;Jeffrey M Gimble;Farshid Guilak

Frequent Co-Authors

Virginia B. Kraus
Virginia B. Kraus Duke University
Wolfgang LiedtkeRegeneron
Wolfgang LiedtkeRegeneron Regeneron (United States)
Jeffrey M. Gimble
Jeffrey M. Gimble Tulane University
Charles A. Gersbach
Charles A. Gersbach Duke University
J. Brice Weinberg
J. Brice Weinberg Duke University
Stefan Zauscher
Stefan Zauscher Duke University
Kam W. Leong
Kam W. Leong Columbia University
David S. Pisetsky
David S. Pisetsky Duke University
Bruce A. Bunnell
Bruce A. Bunnell University of North Texas Health Science Center

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