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Biology and Biochemistry

D-Index
89
Citations
29186
World Ranking
2553
National Ranking
187

Research.com Recognitions

  • 2008 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Chemistry

Overview

Thomas Carell is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a specialized concentration in Molecular Biology, Immunology, Materials Chemistry, Astronomy and Astrophysics, and Organic Chemistry.

Their scientific work covers a broad range of topics, including:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Epigenetics and DNA Methylation
  • Origins and Evolution of Life
  • Advanced biosensing and bioanalysis techniques
  • Interferon and immune responses
  • DNA and Nucleic Acid Chemistry

Thomas Carell has published extensively in notable journals and publication venues. They have contributed 21 publications to both Angewandte Chemie International Edition and Angewandte Chemie, 14 to bioRxiv (Cold Spring Harbor Laboratory), 11 to The Cambridge Structural Database, and 7 to Nature Communications.

Frequent collaborators include Markus Müller, Franziska R. Traube, Mirko Wagner, Eva Korytiaková, and Matthias Heiß, with whom Carell has co-authored multiple papers.

Significant recent publications include:

  • A prebiotically plausible scenario of an RNA-peptide world (2022), published in Nature
  • Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors (2021), published in Science
  • Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals (2020), published in Nature Communications
  • STING agonism turns human T cells into interferon-producing cells but impedes their functionality (2023), published in EMBO Reports
  • Third-Generation Sequencing of Epigenetic DNA (2022), published in Angewandte Chemie International Edition

Thomas Carell was recognized by the German National Academy of Sciences Leopoldina in 2008 for contributions in Chemistry.

Best Publications

  • Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

    Cornelia G. Spruijt;Felix Gnerlich;Arne H. Smits;Toni Pfaffeneder

  • Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

    Daniel Globisch;Martin Münzel;Markus Müller;Stylianos Michalakis

  • DNA--metal base pairs.

    Guido H. Clever;Corinna Kaul;Thomas Carell

  • Click chemistry as a reliable method for the high-density postsynthetic functionalization of alkyne-modified DNA.

    Johannes Gierlich;Glenn A Burley;Philipp M E Gramlich;David M Hammond

  • Thymine Dimerization in DNA is an Ultrafast Photoreaction

    Wolfgang J. Schreier;Tobias E. Schrader;Florian O. Koller;Peter Gilch

  • The Discovery of 5-Formylcytosine in Embryonic Stem Cell DNA†

    Toni Pfaffeneder;Benjamin Hackner;Matthias Truß;Martin Münzel

  • Tumour hypoxia causes DNA hypermethylation by reducing TET activity

    Bernard Thienpont;Jessica Steinbacher;Hui Zhao;Flora D’Anna

  • N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis.

    Raghu R Edupuganti;Simon Geiger;Rik G H Lindeboom;Hailing Shi

  • Postsynthetic DNA Modification through the Copper‐Catalyzed Azide–Alkyne Cycloaddition Reaction

    Philipp M. E. Gramlich;Christian T. Wirges;Antonio Manetto;Thomas Carell

  • Quantification of the sixth DNA base hydroxymethylcytosine in the brain.

    Martin Münzel;Daniel Globisch;Tobias Brückl;Mirko Wagner

  • Crystal Structure of a Photolyase Bound to a CPD-Like DNA Lesion After in Situ Repair

    Alexandra Mees;Tobias Klar;Petra Gnau;Ulrich Hennecke

  • Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

    Gerald W Hsu;Matthias Ober;Thomas Carell;Lorena S Beese

  • Directed DNA Metallization

    Glenn A Burley;Johannes Gierlich;Mohammad R Mofid;Hadar Nir

  • Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

    Sigal Shachar;Omer Ziv;Sharon Avkin;Sheera Adar

  • Programmable self-assembly of metal ions inside artificial DNA duplexes

    Kentaro Tanaka;Kentaro Tanaka;Guido H. Clever;Yusuke Takezawa;Yasuyuki Yamada

  • Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA

    Toni Pfaffeneder;Fabio Spada;Mirko Wagner;Caterina Brandmayr

  • A Novel Procedure for the Synthesis of Libraries Containing Small Organic Molecules

    Thomas Carell;Edward A. Wintner;A. Bashir‐Hashemi;Julius Rebek

  • CPD damage recognition by transcribing RNA polymerase II

    F. Brueckner;U. Hennecke;T. Carell;P. Cramer

  • Click–Click–Click: Single to Triple Modification of DNA

    Philipp M. E. Gramlich;Simon Warncke;Johannes Gierlich;Thomas Carell

  • 5‐Hydroxymethylcytosine, the Sixth Base of the Genome

    Martin Münzel;Daniel Globisch;Thomas Carell

Frequent Co-Authors

Wolfgang Zinth
Wolfgang Zinth Ludwig-Maximilians-Universität München
Guido H. Clever
Guido H. Clever TU Dortmund University
Julius Rebek
Julius Rebek Scripps Research Institute
Martin Biel
Martin Biel Ludwig-Maximilians-Universität München
Heinrich Leonhardt
Heinrich Leonhardt Ludwig-Maximilians-Universität München
Ilme Schlichting
Ilme Schlichting Max Planck Society
Zvi Livneh
Zvi Livneh Weizmann Institute of Science
Ulrich Simon
Ulrich Simon RWTH Aachen University
Patrick Cramer
Patrick Cramer Max Planck Society
Paul Knochel
Paul Knochel Ludwig-Maximilians-Universität München

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