D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 44 Citations 6,922 157 World Ranking 11067 National Ranking 615

Overview

What is she best known for?

The fields of study she is best known for:

  • DNA
  • Gene
  • Enzyme

Her main research concerns DNA, Oligonucleotide, Combinatorial chemistry, Base pair and Click chemistry. Her DNA study frequently draws parallels with other fields, such as Ligation. Her Oligonucleotide study combines topics in areas such as Yield, Nucleic acid thermodynamics, Nucleic acid and Biophysical chemistry.

In her research on the topic of Nucleic acid, Nucleobase and Base analog is strongly related with Organic chemistry. Her Combinatorial chemistry research is multidisciplinary, relying on both Nanotechnology, Hammerhead ribozyme, Chemical ligation, Stem-loop and A-DNA. Afaf H. El-Sagheer interconnects RNA, Hairpin ribozyme, Uracil and VS ribozyme in the investigation of issues within Click chemistry.

Her most cited work include:

  • Click chemistry with DNA (526 citations)
  • Click chemistry with DNA (526 citations)
  • Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry. (231 citations)

What are the main themes of her work throughout her whole career to date?

DNA, Oligonucleotide, Combinatorial chemistry, Biochemistry and Nanotechnology are her primary areas of study. Afaf H. El-Sagheer has included themes like Biophysics, Nucleic acid, Click chemistry and Stereochemistry in her DNA study. Her work in the fields of Oligonucleotide, such as Phosphoramidite, overlaps with other areas such as Alkyne.

Her research in Combinatorial chemistry intersects with topics in Yield, Triazole, Organic chemistry, Azide and Polymerase. Her work in Biochemistry addresses subjects such as Molecular biology, which are connected to disciplines such as Transcription. As a part of the same scientific study, Afaf H. El-Sagheer usually deals with the Nanotechnology, concentrating on Analyte and frequently concerns with Aptamer.

She most often published in these fields:

  • DNA (82.82%)
  • Oligonucleotide (73.13%)
  • Combinatorial chemistry (43.61%)

What were the highlights of her more recent work (between 2019-2021)?

  • Oligonucleotide (73.13%)
  • DNA (82.82%)
  • Nucleic acid (25.55%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Oligonucleotide, DNA, Nucleic acid, Combinatorial chemistry and Cell biology. Her work deals with themes such as Computational biology, Nanotechnology and Click chemistry, which intersect with Oligonucleotide. The DNA study combines topics in areas such as Biophysics, Fluorophore and Circular dichroism.

Her biological study deals with issues like RNA, which deal with fields such as Genome editing. Her Combinatorial chemistry course of study focuses on Polymerase and Ligation and Chemical ligation. Her Cell biology research is multidisciplinary, incorporating elements of Adipose tissue and Enhancer.

Between 2019 and 2021, her most popular works were:

  • Dynamics of the 4D genome during in vivo lineage specification and differentiation. (18 citations)
  • Dynamics of the 4D genome during in vivo lineage specification and differentiation. (18 citations)
  • Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor. (5 citations)

In her most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Enzyme

Afaf H. El-Sagheer mostly deals with DNA, Oligonucleotide, Cleavage, Click chemistry and Computational biology. Her DNA research incorporates themes from Förster resonance energy transfer, Biophysics, Nucleic acid and Fluorophore. Her Nucleic acid study combines topics from a wide range of disciplines, such as RNA, Quantum yield and Uracil.

Her Cleavage study incorporates themes from Nucleotide, Endonuclease, Transcription activator-like effector nuclease, Stereochemistry and Small molecule. Her Click chemistry research includes themes of Cleave and Phenanthroline. Her Computational biology research also works with subjects such as

  • Regulatory sequence that connect with fields like Chromosome conformation capture, Genome, Promoter and Chromatin,
  • Human genetics that intertwine with fields like Gene expression.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Click chemistry with DNA

Afaf H. El-Sagheer;Afaf H. El-Sagheer;Tom Brown.
Chemical Society Reviews (2010)

695 Citations

Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry.

Ravindra Kumar;Afaf El-Sagheer;John Tumpane;Per Lincoln.
Journal of the American Chemical Society (2007)

301 Citations

Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology

Afaf H. El-Sagheer;Tom Brown.
Accounts of Chemical Research (2012)

213 Citations

Nucleic acid base analog fret-pair facilitating detailed structural measurements in nucleic acid containing systems

Karl Börjesson;Søren Preus;Afaf H. El-Sagheer;Tom Brown.
Journal of the American Chemical Society (2009)

177 Citations

New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes

Afaf H. El-Sagheer;Tom Brown.
Proceedings of the National Academy of Sciences of the United States of America (2010)

158 Citations

Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli

Afaf H. El-Sagheer;A. Pia Sanzone;Rachel Gao;Ali Tavassoli.
Proceedings of the National Academy of Sciences of the United States of America (2011)

154 Citations

Highly Sensitive DNA Sensor Based on Upconversion Nanoparticles and Graphene Oxide

P. Alonso-Cristobal;P. Vilela;A. El-Sagheer;E. Lopez-Cabarcos.
ACS Applied Materials & Interfaces (2015)

149 Citations

Synthesis and Polymerase Chain Reaction Amplification of DNA Strands Containing an Unnatural Triazole Linkage

Afaf H El-Sagheer;Tom Brown.
Journal of the American Chemical Society (2009)

140 Citations

Fast copper-free click DNA ligation by the ring-strain promoted alkyne-azide cycloaddition reaction.

Montserrat Shelbourne;Xiong Chen;Tom Brown;Afaf H. El-Sagheer;Afaf H. El-Sagheer.
Chemical Communications (2011)

126 Citations

Synthesis of Trifluoromethylnaphthalenes

John M Mellor;Afaf H El-Sagheer;El-Sayed H El-Tamany;Reda N Metwally.
Tetrahedron (2000)

125 Citations

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