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Jean-Jacques Vasseur

Jean-Jacques Vasseur

D-Index & Metrics

Chemistry

D-Index
48
Citations
9242
World Ranking
15160
National Ranking
645

Overview

Jean-Jacques Vasseur is affiliated with the University of Montpellier in France. Their academic contributions primarily span the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. The scientist's research deeply engages with Molecular Biology, Infectious Diseases, Organic Chemistry, Epidemiology, and Electrical and Electronic Engineering as subfields of study.

The main topics of their work encompass advanced biosensing and bioanalysis techniques, RNA modifications and cancer, DNA and nucleic acid chemistry, RNA interference and gene delivery, RNA and protein synthesis mechanisms, HIV/AIDS drug development and treatment, and click chemistry and its applications.

Examples of recent publications by Jean-Jacques Vasseur include:

  • FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell (2021, Nature Communications)
  • Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase (2020, European Journal of Medicinal Chemistry)
  • Modified internucleoside linkages for nuclease-resistant oligonucleotides (2020, RSC Chemical Biology)
  • Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues (2022, Journal of Medicinal Chemistry)
  • A modular spring-loaded actuator for mechanical activation of membrane proteins (2022, Nature Communications)

The scientist has published multiple works in several recurring venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • European Journal of Organic Chemistry
  • Nature Communications
  • European Journal of Medicinal Chemistry

Jean-Jacques Vasseur frequently collaborates with several co-authors, including:

  • Françoise Debart with 26 joint publications
  • Michaël Smietana with 20 joint publications
  • Étienne Decroly with 14 joint publications
  • Bruno Canard with 12 joint publications
  • F. Morvan with 10 joint publications

Best Publications

  • Backbone modified oligonucleotide analogues

    Phillip Dan Cook;Yogesh Shantilal Sanghvi;Jean Jacques Vasseur;Francoise Debart

  • Microwave Assisted “Click” Chemistry for the Synthesis of Multiple Labeled-Carbohydrate Oligonucleotides on Solid Support†

    Camille Bouillon;Albert Meyer;Sébastien Vidal;Anne Jochum

  • FTO controls reversible m6Am RNA methylation during snRNA biogenesis.

    Jan Mauer;Miriam Sindelar;Vladimir Despic;Théo Guez

  • DNA‐Based Carbohydrate Biochips: A Platform for Surface Glyco‐Engineering

    Yann Chevolot;Camille Bouillon;Sébastien Vidal;François Morvan

  • Recent developments in alkyne borylations

    Renaud Barbeyron;Erica Benedetti;Janine Cossy;Jean-Jacques Vasseur

  • Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

    Jean Jacques Vasseur;Francoise Debart;Yogesh S. Sanghvi;P. Dan Cook

  • Boron and nucleic acid chemistries: merging the best of both worlds

    Anthony R. Martin;Jean-Jacques Vasseur;Michael Smietana

  • Fucosylated pentaerythrityl phosphodiester oligomers (PePOs): automated synthesis of DNA-based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL).

    François Morvan;Albert Meyer;Anne Jochum;Charles Sabin

  • Phosphotriester oligonucleotides, amidities and method of preparation

    Jean-Louis Imbach;Gilles Gosselin;Bernard Rayner;Muthiah Manoharan

  • Three‐Component Reaction Using the Bestmann–Ohira Reagent: A Regioselective Synthesis of Phosphonyl Pyrazole Rings

    Kishor Mohanan;Anthony R Martin;Loic Toupet;Michael Smietana

  • The pro-oligonucleotide approach: Solid phase synthesis and preliminary evaluation of model pro-dodecathymidylates

    Guilhem Tosquellas;Karine Alvarez;Christelle Dell'Aquila;François Morvan

  • Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry

    Gwladys Pourceau;Albert Meyer;Jean-Jacques Vasseur;François Morvan

  • A Base‐Labile Group for 2′‐OH Protection of Ribonucleosides: A Major Challenge for RNA Synthesis

    Thomas Lavergne;Jean-Rémi Bertrand;Jean-Jacques Vasseur;Françoise Debart

  • Oligodeoxynucleoside Phosphoramidates (P-NH2): Synthesis and Thermal Stability of Duplexes With DNA and RNA Targets

    Suzanne Peyrottes;Jean-Jacques Vasseur;Jean-Louis Imbach;Bernard Rayner

  • High-yield production of short GpppA- and 7MeGpppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2′O positions

    F. Peyrane;B. Selisko;E. Decroly;Jean-Jacques Vasseur

  • New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves.

    Jory Lietard;Albert Meyer;Jean-Jacques Vasseur;François Morvan

  • Azide solid support for 3'-conjugation of oligonucleotides and their circularization by click chemistry.

    Gwladys Pourceau;Albert Meyer;Jean-Jacques Vasseur;François Morvan

  • Design of triazole-tethered glycoclusters exhibiting three different spatial arrangements and comparative study of their affinities towards PA-IL and RCA 120 by using a dna-based glycoarray.

    Lisa Moni;Gwladys Pourceau;Jing Zhang;Albert Meyer

  • Chemical modifications to improve the cellular uptake of oligonucleotides.

    Francoise Debart;Said Abes;Gaelle Deglane;Hong M. Moulton

  • OLIGONUCLEOTIDE MIMICS FOR ANTISENSE THERAPEUTICS : SOLUTION PHASE AND AUTOMATED SOLID-SUPPORT SYNTHESIS OF MMI LINKED OLIGOMERS

    François Morvan;Yogesh S. Sanghvi;Michel Perbost;Jean-Jacques Vasseur

  • Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.

    Wahiba Aouadi;Wahiba Aouadi;Alexandre Blanjoie;Jean Jacques Vasseur;Françoise Debart

  • Molecular basis for nucleotide conservation at the ends of the dengue virus genome.

    Barbara Selisko;Supanee Potisopon;Rym Agred;Stéphane Priet

  • X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.

    Guido C. Paesen;Axelle Collet;Corinne Sallamand;Françoise Debart

  • Impact of the Guanidinium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides

    Gaëlle Deglane;Saïd Abes;Thibaut Michel;Paul Prévot

Frequent Co-Authors

Jean-Louis Imbach
Jean-Louis Imbach Centre national de la recherche scientifique, CNRS
Bruno Canard
Bruno Canard Aix-Marseille University
Etienne Decroly
Etienne Decroly Aix-Marseille University
Christophe Pannecouque
Christophe Pannecouque Rega Institute for Medical Research
Anne Imberty
Anne Imberty Grenoble Alpes University
Bruno Coutard
Bruno Coutard Aix-Marseille University
Janine Cossy
Janine Cossy ESPCI Paris
Samie R. Jaffrey
Samie R. Jaffrey Cornell University
Loïc Toupet
Loïc Toupet University of Rennes
Johan Neyts
Johan Neyts Rega Institute for Medical Research

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