D-Index & Metrics Best Publications
Hiroshi Takeshima

Hiroshi Takeshima

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 77 Citations 23,303 195 World Ranking 2085 National Ranking 125

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Hiroshi Takeshima mainly focuses on Cell biology, Skeletal muscle, Ryanodine receptor, Endoplasmic reticulum and Internal medicine. His studies deal with areas such as T-type calcium channel, Membrane protein and Cell membrane as well as Cell biology. His Skeletal muscle research is multidisciplinary, incorporating perspectives in Calcium, Calcium signaling, Depolarization, Muscle contraction and Myocyte.

His Ryanodine receptor research integrates issues from Molecular biology, Calcium channel and Voltage-dependent calcium channel. His study on T-tubule is often connected to Coupling as part of broader study in Endoplasmic reticulum. As a member of one scientific family, Hiroshi Takeshima mostly works in the field of Internal medicine, focusing on Endocrinology and, on occasion, Nociceptin receptor, Nociception and Hyperalgesia.

His most cited work include:

  • Primary structure of the receptor for calcium channel blockers from skeletal muscle (1201 citations)
  • Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. (967 citations)
  • Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel (841 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Ryanodine receptor, Endoplasmic reticulum, Internal medicine and Endocrinology. His studies examine the connections between Cell biology and genetics, as well as such issues in Cell membrane, with regards to Vesicle. Hiroshi Takeshima has researched Ryanodine receptor in several fields, including Biophysics and Voltage-dependent calcium channel.

His Endoplasmic reticulum study is concerned with Biochemistry in general. As a part of the same scientific family, Hiroshi Takeshima mostly works in the field of Endocrinology, focusing on Nociceptin receptor and, on occasion, Neuroscience, Nociception, Pharmacology and Opioid receptor. His Skeletal muscle study which covers Molecular biology that intersects with Messenger RNA.

He most often published in these fields:

  • Cell biology (48.86%)
  • Ryanodine receptor (35.23%)
  • Endoplasmic reticulum (32.67%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (48.86%)
  • Endoplasmic reticulum (32.67%)
  • Ryanodine receptor (35.23%)

In recent papers he was focusing on the following fields of study:

Hiroshi Takeshima focuses on Cell biology, Endoplasmic reticulum, Ryanodine receptor, Skeletal muscle and Biophysics. His studies in Cell biology integrate themes in fields like Cell, Knockout mouse and Transmembrane protein. His Endoplasmic reticulum research is within the category of Biochemistry.

His study in Ryanodine receptor is interdisciplinary in nature, drawing from both Endocrinology and SERCA. In Skeletal muscle, Hiroshi Takeshima works on issues like Muscle contraction, which are connected to Receptor and Unfolded protein response. His studies in Biophysics integrate themes in fields like Membrane, TRPM7 and Patch clamp.

Between 2013 and 2021, his most popular works were:

  • Treatment of acute lung injury by targeting MG53-mediated cell membrane repair (61 citations)
  • Ca2+ microdomains organized by junctophilins (56 citations)
  • Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons (47 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His scientific interests lie mostly in Cell biology, Endoplasmic reticulum, Ryanodine receptor, Intracellular and Biophysics. Hiroshi Takeshima combines subjects such as Cell and Knockout mouse with his study of Cell biology. The concepts of his Endoplasmic reticulum study are interwoven with issues in Skeletal muscle, Cell type and Calcium signaling.

His work in Skeletal muscle is not limited to one particular discipline; it also encompasses Myocyte. His biological study spans a wide range of topics, including Endocrinology, Gating and Ion channel. Hiroshi Takeshima has included themes like Staining, Calcification, Bone tissue and Mineralization in his Biophysics study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Primary structure of the receptor for calcium channel blockers from skeletal muscle

Tsutomu Tanabe;Hiroshi Takeshima;Atsushi Mikami;Veit Flockerzi.
Nature (1987)

1612 Citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor.

Hiroshi Takeshima;Seiichiro Nishimura;Takeshi Matsumoto;Hiroyuki Ishida.
Nature (1989)

1327 Citations

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

Atsushi Mikami;Keiji Imoto;Tsutomu Tanabe;Tetsuhiro Niidome.
Nature (1989)

1128 Citations

Existence of distinct sodium channel messenger RNAs in rat brain

Masaharu Noda;Takayuki Ikeda;Toshiaki Kayano;Harukazu Suzuki.
Nature (1986)

1031 Citations

Junctophilins: a novel family of junctional membrane complex proteins.

Hiroshi Takeshima;Hiroshi Takeshima;Shinji Komazaki;Miyuki Nishi;Miyuki Nishi;Masamitsu Iino.
Molecular Cell (2000)

672 Citations

Spatiotemporal dynamics of inositol 1,4,5-trisphosphate that underlies complex Ca2+ mobilization patterns.

Kenzo Hirose;Shiro Kadowaki;Mao Tanabe;Hiroshi Takeshima.
Science (1999)

618 Citations

Expression of functional sodium channels from cloned cDNA

Masaharu Noda;Takayuki Ikeda;Harukazu Suzuki;Hiroshi Takeshima.
Nature (1986)

597 Citations

cDNA cloning and regional distribution of a novel member of the opioid receptor family

Kazuhiko Fukuda;Shigehisa Kato;Kenjiro Mori;Miyuki Nishi.
FEBS Letters (1994)

584 Citations

Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain.

Yasuhiro Hakamata;Junichi Nakai;Hiroshi Takeshima;Keiji Imoto.
FEBS Letters (1992)

531 Citations

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.

Shinichiro Yamamoto;Shunichi Shimizu;Shigeki Kiyonaka;Nobuaki Takahashi.
Nature Medicine (2008)

514 Citations

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