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Hiroshi Takeshima

Hiroshi Takeshima

Kyoto University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
27255
World Ranking
2956
National Ranking
185

Hiroshi Takeshima publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hiroshi Takeshima sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 376 publications — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hiroshi Takeshima D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroshi Takeshima sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 86 D-Index — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hiroshi Takeshima is affiliated with Kyoto University in Japan. Their research focuses primarily on the intersections of biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to the molecular biology subfield, with particular emphasis on ion channel regulation and related physiological processes.

The main research topics covered by Takeshima include:

  • Ion channel regulation and function
  • Ion transport and channel regulation
  • Cancer treatment and pharmacology
  • Metabolism, diabetes, and cancer
  • Cardiac electrophysiology and arrhythmias
  • Ion channels and receptors
  • Muscle physiology and disorders

Takeshima has published numerous papers with a focus on molecular mechanisms underlying cardiovascular and neurological conditions. Selected recent publications include:

  • "Predictive Value of the Cardio-Ankle Vascular Index for Cardiovascular Events in Patients at Cardiovascular Risk", 2021, Journal of the American Heart Association
  • "Parkinson's disease-associated ATP13A2/PARK9 functions as a lysosomal H+,K+-ATPase", 2023, Nature Communications
  • "Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway", 2020, Nature Communications
  • "Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sIAHP, and its potentiation in hippocampal pyramidal neurons", 2020, PLoS ONE
  • "Structure, Function, and Regulation of the Junctophilin Family", 2023, Annual Review of Physiology

The scientist has frequently collaborated with colleagues such as Miyuki Nishi, Atsuhiko Ichimura, Takuto Fujii, Takahiro Shimizu, and Yoshiaki Tabuchi, reflecting interdisciplinary teamwork in various research efforts.

Takeshima's research output has appeared in several well-known publication venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Nature Communications
  • PLoS ONE
  • iScience

Best Publications

  • Primary structure of the receptor for calcium channel blockers from skeletal muscle

    Tsutomu Tanabe;Hiroshi Takeshima;Atsushi Mikami;Veit Flockerzi

  • Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor.

    Hiroshi Takeshima;Seiichiro Nishimura;Takeshi Matsumoto;Hiroyuki Ishida

  • Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

    Atsushi Mikami;Keiji Imoto;Tsutomu Tanabe;Tetsuhiro Niidome

  • Existence of distinct sodium channel messenger RNAs in rat brain

    Masaharu Noda;Takayuki Ikeda;Toshiaki Kayano;Harukazu Suzuki

  • Junctophilins: a novel family of junctional membrane complex proteins.

    Hiroshi Takeshima;Hiroshi Takeshima;Shinji Komazaki;Miyuki Nishi;Miyuki Nishi;Masamitsu Iino

  • TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

    Shinichiro Yamamoto;Shunichi Shimizu;Shigeki Kiyonaka;Nobuaki Takahashi

  • Expression of functional sodium channels from cloned cDNA

    Masaharu Noda;Takayuki Ikeda;Harukazu Suzuki;Hiroshi Takeshima

  • Spatiotemporal dynamics of inositol 1,4,5-trisphosphate that underlies complex Ca2+ mobilization patterns.

    Kenzo Hirose;Shiro Kadowaki;Mao Tanabe;Hiroshi Takeshima

  • cDNA cloning and regional distribution of a novel member of the opioid receptor family

    Kazuhiko Fukuda;Shigehisa Kato;Kenjiro Mori;Miyuki Nishi

  • Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain.

    Yasuhiro Hakamata;Junichi Nakai;Hiroshi Takeshima;Keiji Imoto

  • MG53 nucleates assembly of cell membrane repair machinery

    Chuanxi Cai;Haruko Masumiya;Noah Weisleder;Noriyuki Matsuda

  • Primary structure and functional expression from cDN A of the cardiac ryanodine receptor/calcium release channel

    Junichi Nakai;Toshiaki Imagawa;Yasuhiro Hakamata;Munekazu Shigekawa

  • Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene

    Takeshima H;Iino M;Takekura H;Nishi M

  • Primary structures and expression from cDNAs of rat opioid receptor δ-and μ-subtypes

    Kazuhiko Fukuda;Shigehisa Kato;Kenjiro Mori;Miyuki Nishi

  • Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors

    Toshiya Manabe;Yukihiro Noda;Takayoshi Mamiya;Hiroyuki Katagiri

  • Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor

    Miyuki Nishi;Takeshi Houtani;Yukihiro Noda;Takayoshi Mamiya

  • Multiple types of ryanodine receptor/Ca2+ release channels are differentially expressed in rabbit brain

    T Furuichi;D Furutama;Y Hakamata;J Nakai

  • Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle.

    Xin-Hui Sun;F. Protasi;M. Takahashi;H. Takeshima

  • Membrane Repair Defects in Muscular Dystrophy Are Linked to Altered Interaction between MG53, Caveolin-3, and Dysferlin

    Chuanxi Cai;Noah Weisleder;Jae-Kyun Ko;Shinji Komazaki

  • Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.

    Hiroshi Takeshima;Shinji Komazaki;Kenzo Hirose;Miyuki Nishi

Frequent Co-Authors

Miyuki Nishi
Miyuki Nishi Kyoto University
Jianjie Ma
Jianjie Ma The Ohio State University
Masamitsu Iino
Masamitsu Iino Nihon University
Tetsuo Noda
Tetsuo Noda Japanese Foundation For Cancer Research
Francesco Zorzato
Francesco Zorzato University of Ferrara
Susan Treves
Susan Treves University Hospital of Basel
Toshitaka Nabeshima
Toshitaka Nabeshima Meijo University
Shosaku Numa
Shosaku Numa Kyoto University
Yukihiro Noda
Yukihiro Noda Meijo University
Xiaoli Zhao
Xiaoli Zhao Tongji University

External Links

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Best Scientists Citing Hiroshi Takeshima

William A. Catterall

William A. Catterall

University of Washington

Publications: 135

Yasuo Mori

Yasuo Mori

Kyoto University

Publications: 83

Susan Treves

Susan Treves

University Hospital of Basel

Publications: 74

Gerhard Meissner

Gerhard Meissner

University of North Carolina at Chapel Hill

Publications: 74

Jianjie Ma

Jianjie Ma

The Ohio State University

Publications: 74

Francesco Zorzato

Francesco Zorzato

University of Ferrara

Publications: 71

Girolamo Calo

Girolamo Calo

University of Ferrara

Publications: 67

Katsuhiko Mikoshiba

Katsuhiko Mikoshiba

ShanghaiTech University

Publications: 62

Kurt G. Beam

Kurt G. Beam

University of Colorado Denver

Publications: 61

Vincenzo Sorrentino

Vincenzo Sorrentino

University of Siena

Publications: 55

Remo Guerrini

Remo Guerrini

University of Ferrara

Publications: 55

Paul D. Allen

Paul D. Allen

St James's University Hospital

Publications: 54

Isaac N. Pessah

Isaac N. Pessah

University of California, Davis

Publications: 53

Franz Hofmann

Franz Hofmann

Technical University of Munich

Publications: 52

Kevin P. Campbell

Kevin P. Campbell

University of Iowa

Publications: 52

Stephen G. Waxman

Stephen G. Waxman

Yale University

Publications: 51

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