What is he best known for?
The fields of study he is best known for:
Ryanodine receptor, Internal medicine, Cell biology, Endocrinology and RYR1 are his primary areas of study.
Vincenzo Sorrentino combines subjects such as Skeletal muscle and Gene isoform with his study of Ryanodine receptor.
His Internal medicine study integrates concerns from other disciplines, such as Proband and Human brain.
His Cell biology research includes themes of Receptor, Clinical uses of mesenchymal stem cells and Stem cell transplantation for articular cartilage repair.
The various areas that Vincenzo Sorrentino examines in his Endocrinology study include Temporal cortex and Knockout mouse.
Vincenzo Sorrentino has included themes like Terminal cisternae and Molecular biology in his RYR1 study.
His most cited work include:
- Mutations in the Cardiac Ryanodine Receptor Gene (hRyR2) Underlie Catecholaminergic Polymorphic Ventricular Tachycardia (1139 citations)
- The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. (464 citations)
- Ryanodine receptors: how many, where and why? (261 citations)
What are the main themes of his work throughout his whole career to date?
Vincenzo Sorrentino mostly deals with Ryanodine receptor, Cell biology, Endoplasmic reticulum, Skeletal muscle and Internal medicine.
His research in Ryanodine receptor intersects with topics in Voltage-dependent calcium channel and Gene isoform.
Vincenzo Sorrentino has researched Endoplasmic reticulum in several fields, including Sarcolemma, SR protein, Depolarization, Transmembrane domain and Muscle contraction.
Vincenzo Sorrentino interconnects Cardiac muscle and Myopathy in the investigation of issues within Skeletal muscle.
His work in Internal medicine addresses issues such as Endocrinology, which are connected to fields such as Receptor, Calcium and Knockout mouse.
His studies deal with areas such as Molecular biology, Malignant hyperthermia and Gene as well as RYR1.
He most often published in these fields:
- Ryanodine receptor (47.87%)
- Cell biology (40.43%)
- Endoplasmic reticulum (28.19%)
What were the highlights of his more recent work (between 2012-2020)?
- Cell biology (40.43%)
- Skeletal muscle (23.94%)
- Ryanodine receptor (47.87%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, Skeletal muscle, Ryanodine receptor, Endoplasmic reticulum and Biochemistry.
His study in Cell biology is interdisciplinary in nature, drawing from both Molecular biology and Ankyrin.
The Skeletal muscle study combines topics in areas such as Missense mutation, Embryonic stem cell, Myocyte, Sarcomere and Myopathy.
His Ryanodine receptor research is within the category of Receptor.
The concepts of his Endoplasmic reticulum study are interwoven with issues in Voltage-dependent calcium channel, Calcium signaling, Fusion protein, Transmembrane domain and Gene isoform.
He focuses mostly in the field of Biochemistry, narrowing it down to topics relating to Muscle contraction and, in certain cases, Excitation–contraction coupling.
Between 2012 and 2020, his most popular works were:
- Bcl-2 binds to and inhibits ryanodine receptors (48 citations)
- Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity. (40 citations)
- A Mutation in the CASQ1 Gene Causes a Vacuolar Myopathy with Accumulation of Sarcoplasmic Reticulum Protein Aggregates (36 citations)
In his most recent research, the most cited papers focused on:
Vincenzo Sorrentino spends much of his time researching Cell biology, Ryanodine receptor, Skeletal muscle, Calsequestrin and Biochemistry.
His Cell biology study combines topics in areas such as Protein structure and Immunology.
His work on RYR1 as part of general Ryanodine receptor research is frequently linked to Enflurane, thereby connecting diverse disciplines of science.
His research investigates the connection between Skeletal muscle and topics such as Myopathy that intersect with issues in Mutation and Frameshift mutation.
The various areas that Vincenzo Sorrentino examines in his Calsequestrin study include Missense mutation, Mutant and SR protein.
In his research, Peptide sequence, Ectopic expression, Calcium signaling, Voltage-dependent calcium channel and Inositol trisphosphate receptor is intimately related to Molecular biology, which falls under the overarching field of Endoplasmic reticulum.
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