Xander H.T. Wehrens spends much of his time researching Internal medicine, Endocrinology, Ryanodine receptor, Ryanodine receptor 2 and Heart failure. His Internal medicine study frequently intersects with other fields, such as Cardiology. Xander H.T. Wehrens has researched Endocrinology in several fields, including Transgene, Endoplasmic reticulum, Atrial fibrillation, Electrocardiography and Sudden cardiac death.
The study incorporates disciplines such as Ventricular tachycardia and Calcium channel in addition to Ryanodine receptor. The Ryanodine receptor 2 study combines topics in areas such as Contractility and Ca2+/calmodulin-dependent protein kinase, Protein kinase A, Phosphorylation. His Heart failure study deals with Myocardial infarction intersecting with Calcium, Cyclic adenosine monophosphate and Ryanodine receptor complex.
Xander H.T. Wehrens mainly investigates Internal medicine, Endocrinology, Ryanodine receptor 2, Ryanodine receptor and Cardiology. His work carried out in the field of Internal medicine brings together such families of science as Endoplasmic reticulum and Ca2+/calmodulin-dependent protein kinase. Xander H.T. Wehrens works mostly in the field of Endocrinology, limiting it down to concerns involving JPH2 and, occasionally, Hypertrophic cardiomyopathy.
His research in Ryanodine receptor 2 tackles topics such as Phosphorylation which are related to areas like Kinase. Xander H.T. Wehrens interconnects Calmodulin, Contractility, Pharmacology and Protein kinase A in the investigation of issues within Ryanodine receptor. His work on Heart disease, Electrocardiography, Ventricular tachycardia and Ventricle as part of general Cardiology study is frequently linked to In patient, therefore connecting diverse disciplines of science.
His scientific interests lie mostly in Internal medicine, Atrial fibrillation, Ryanodine receptor 2, Cell biology and Cardiology. His studies in Internal medicine integrate themes in fields like Endocrinology and Ca2+/calmodulin-dependent protein kinase. His work deals with themes such as Myosin light-chain kinase, Dephosphorylation, Protein subunit, Protein phosphatase 1 and Pharmacology, which intersect with Atrial fibrillation.
His Ryanodine receptor 2 research entails a greater understanding of Ryanodine receptor. The concepts of his Ryanodine receptor study are interwoven with issues in Genome editing and Protein kinase A. His Cardiology research includes elements of Biomarker, Gene and Epilepsy.
Xander H.T. Wehrens mostly deals with Internal medicine, Atrial fibrillation, Ca2+/calmodulin-dependent protein kinase, Endocrinology and Ryanodine receptor 2. Xander H.T. Wehrens has included themes like Gene isoform, RNA splicing and Exon in his Internal medicine study. His Atrial fibrillation research includes themes of Endoplasmic reticulum, Immune system and Pathogenesis.
His Endocrinology research is mostly focused on the topic Myocyte. His Ryanodine receptor 2 research is included under the broader classification of Ryanodine receptor. His work on Catecholaminergic polymorphic ventricular tachycardia as part of general Ryanodine receptor study is frequently linked to Potential impact, bridging the gap between disciplines.
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Correction: Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases
Yuejin Wu;Tyler P. Rasmussen;Olha M. Koval;Mei-ling A. Joiner.
Nature Communications (2015)
FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death
Xander H T Wehrens;Stephan E. Lehnart;Fannie Huang;John A. Vest.
Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor
Xander H.T. Wehrens;Stephan E. Lehnart;Steven R. Reiken;Andrew R. Marks.
Circulation Research (2004)
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation
Niels Voigt;Na Li;Qiongling Wang;Wei Wang.
Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
Sameer Ather;Wenyaw Chan;Biykem Bozkurt;Biykem Bozkurt;David Aguilar.
Journal of the American College of Cardiology (2012)
Protection from Cardiac Arrhythmia Through Ryanodine Receptor- Stabilizing Protein Calstabin2
Xander H. T. Wehrens;Stephan E. Lehnart;Steven R. Reiken;Shi-Xian Deng.
Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias
Stephan E. Lehnart;Xander H.T. Wehrens;Steven Reiken;Sunita Warrier.
Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation
Niels Voigt;Jordi Heijman;Qiongling Wang;David Y. Chiang.
INTRACELLULAR CALCIUM RELEASE AND CARDIAC DISEASE
Xander H T Wehrens;Stephan E Lehnart;Andrew R Marks.
Annual Review of Physiology (2005)
Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice
Mihail G. Chelu;Mihail G. Chelu;Satyam Sarma;Subeena Sood;Sufen Wang;Sufen Wang.
Journal of Clinical Investigation (2009)
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