D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 75 Citations 21,111 310 World Ranking 14489 National Ranking 7471

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Genetics

Xander H.T. Wehrens spends much of his time researching Internal medicine, Endocrinology, Ryanodine receptor, Ryanodine receptor 2 and Heart failure. His Internal medicine study frequently intersects with other fields, such as Cardiology. Xander H.T. Wehrens has researched Endocrinology in several fields, including Transgene, Endoplasmic reticulum, Atrial fibrillation, Electrocardiography and Sudden cardiac death.

The study incorporates disciplines such as Ventricular tachycardia and Calcium channel in addition to Ryanodine receptor. The Ryanodine receptor 2 study combines topics in areas such as Contractility and Ca2+/calmodulin-dependent protein kinase, Protein kinase A, Phosphorylation. His Heart failure study deals with Myocardial infarction intersecting with Calcium, Cyclic adenosine monophosphate and Ryanodine receptor complex.

His most cited work include:

  • Correction: Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases (843 citations)
  • FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death (621 citations)
  • Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor (510 citations)

What are the main themes of his work throughout his whole career to date?

Xander H.T. Wehrens mainly investigates Internal medicine, Endocrinology, Ryanodine receptor 2, Ryanodine receptor and Cardiology. His work carried out in the field of Internal medicine brings together such families of science as Endoplasmic reticulum and Ca2+/calmodulin-dependent protein kinase. Xander H.T. Wehrens works mostly in the field of Endocrinology, limiting it down to concerns involving JPH2 and, occasionally, Hypertrophic cardiomyopathy.

His research in Ryanodine receptor 2 tackles topics such as Phosphorylation which are related to areas like Kinase. Xander H.T. Wehrens interconnects Calmodulin, Contractility, Pharmacology and Protein kinase A in the investigation of issues within Ryanodine receptor. His work on Heart disease, Electrocardiography, Ventricular tachycardia and Ventricle as part of general Cardiology study is frequently linked to In patient, therefore connecting diverse disciplines of science.

He most often published in these fields:

  • Internal medicine (65.46%)
  • Endocrinology (41.78%)
  • Ryanodine receptor 2 (38.16%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (65.46%)
  • Atrial fibrillation (23.36%)
  • Ryanodine receptor 2 (38.16%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Internal medicine, Atrial fibrillation, Ryanodine receptor 2, Cell biology and Cardiology. His studies in Internal medicine integrate themes in fields like Endocrinology and Ca2+/calmodulin-dependent protein kinase. His work deals with themes such as Myosin light-chain kinase, Dephosphorylation, Protein subunit, Protein phosphatase 1 and Pharmacology, which intersect with Atrial fibrillation.

His Ryanodine receptor 2 research entails a greater understanding of Ryanodine receptor. The concepts of his Ryanodine receptor study are interwoven with issues in Genome editing and Protein kinase A. His Cardiology research includes elements of Biomarker, Gene and Epilepsy.

Between 2017 and 2021, his most popular works were:

  • Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. (125 citations)
  • YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. (64 citations)
  • Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation (30 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Genetics

Xander H.T. Wehrens mostly deals with Internal medicine, Atrial fibrillation, Ca2+/calmodulin-dependent protein kinase, Endocrinology and Ryanodine receptor 2. Xander H.T. Wehrens has included themes like Gene isoform, RNA splicing and Exon in his Internal medicine study. His Atrial fibrillation research includes themes of Endoplasmic reticulum, Immune system and Pathogenesis.

His Endocrinology research is mostly focused on the topic Myocyte. His Ryanodine receptor 2 research is included under the broader classification of Ryanodine receptor. His work on Catecholaminergic polymorphic ventricular tachycardia as part of general Ryanodine receptor study is frequently linked to Potential impact, bridging the gap between disciplines.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Correction: Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases

Yuejin Wu;Tyler P. Rasmussen;Olha M. Koval;Mei-ling A. Joiner.
Nature Communications (2015)

1556 Citations

FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death

Xander H T Wehrens;Stephan E. Lehnart;Fannie Huang;John A. Vest.
Cell (2003)

854 Citations

Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor

Xander H.T. Wehrens;Stephan E. Lehnart;Steven R. Reiken;Andrew R. Marks.
Circulation Research (2004)

742 Citations

Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation

Niels Voigt;Na Li;Qiongling Wang;Wei Wang.
Circulation (2012)

680 Citations

Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction

Sameer Ather;Wenyaw Chan;Biykem Bozkurt;Biykem Bozkurt;David Aguilar.
Journal of the American College of Cardiology (2012)

676 Citations

Protection from Cardiac Arrhythmia Through Ryanodine Receptor- Stabilizing Protein Calstabin2

Xander H. T. Wehrens;Stephan E. Lehnart;Steven R. Reiken;Shi-Xian Deng.
Science (2004)

551 Citations

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Stephan E. Lehnart;Xander H.T. Wehrens;Steven Reiken;Sunita Warrier.
Cell (2005)

550 Citations

Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation

Niels Voigt;Jordi Heijman;Qiongling Wang;David Y. Chiang.
Circulation (2014)

418 Citations

INTRACELLULAR CALCIUM RELEASE AND CARDIAC DISEASE

Xander H T Wehrens;Stephan E Lehnart;Andrew R Marks.
Annual Review of Physiology (2005)

416 Citations

Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice

Mihail G. Chelu;Mihail G. Chelu;Satyam Sarma;Subeena Sood;Sufen Wang;Sufen Wang.
Journal of Clinical Investigation (2009)

406 Citations

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