World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
12097
World Ranking
10380
National Ranking
4508

Héctor H. Valdivia publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Héctor H. Valdivia sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 218 publications — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Héctor H. Valdivia D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Héctor H. Valdivia sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Héctor H. Valdivia is affiliated with the University of Wisconsin-Madison in the United States. Their research focuses predominantly on fields within medicine and biochemistry, genetics, and molecular biology. The scientist's work spans multiple subfields including cardiology and cardiovascular medicine, molecular biology, physiology, genetics, and oncology.

The main topics addressed in their research include:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Cardiovascular effects of exercise
  • Receptor mechanisms and signaling
  • Nicotinic acetylcholine receptors study
  • Adipose tissue and metabolism
  • Venomous animal envenomation and studies

Valdivia has published extensively in multiple academic venues, with a frequent presence in:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • Journal of Molecular and Cellular Cardiology
  • Circulation

Their recent publications include:

  • "Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation" (2021), Circulation Research
  • "Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation" (2023), Science Advances
  • "Mechanisms of ryanodine receptor 2 dysfunction in heart failure" (2020), Nature Reviews Cardiology
  • "Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways" (2023), Cellular and Molecular Life Sciences
  • "Tetrodotoxin-Sensitive Neuronal-Type Na + Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation" (2020), Journal of the American Heart Association

Frequent collaborators in their work include Carmen R. Valdivia, Francisco Alvarado, Wenxuan Cai, Filip Van Petegem, and Holly Dooge. These coauthors have published multiple papers alongside Héctor H. Valdivia, contributing to research on cardiac and molecular physiology topics.

Best Publications

  • Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.

    A. M. Gómez;H. H. Valdivia;H. Cheng;Miriam R. Lederer

  • The brain ryanodine receptor: a caffeine-sensitive calcium release channel

    Peter S. McPhersonx;Young Kee Kim;Hector Valdivia;C. Michael Knudson

  • Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation

    H. H. Valdivia;J. H. Kaplan;G. C. R. Ellis-Davies;W. J. Lederer

  • Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: A molecular autopsy of 49 medical examiner/coroner's cases

    David J. Tester;Daniel B. Spoon;Hector H. Valdivia;Jonathan C. Makielski

  • Abnormal Ca2+ Release, but Normal Ryanodine Receptors, in Canine and Human Heart Failure

    Ming Tao Jiang;Andrew J. Lokuta;Emily F. Farrell;Matthew R. Wolff

  • Scorpion venom components that affect ion-channels function.

    V. Quintero-Hernández;J.M. Jiménez-Vargas;G.B. Gurrola;G.B. Gurrola;H.H.F. Valdivia

  • Luminal Ca2+ Controls Termination and Refractory Behavior of Ca2+-Induced Ca2+ Release in Cardiac Myocytes

    Dmitry Terentyev;Serge Viatchenko-Karpinski;Héctor H. Valdivia;Ariel L. Escobar

  • Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling

    Carlo G. Tocchetti;Wang Wang;Jeffrey P. Froehlich;Sabine Huke

  • Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism.

    A J Lokuta;T B Rogers;W J Lederer;H H Valdivia

  • The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart.

    Rui Ping Xiao;Hector H. Valdivia;Konstantin Bogdanov;Carmen Valdivia

  • Depletion of T-tubules and specific subcellular changes in sarcolemmal proteins in tachycardia-induced heart failure

    Ravi C. Balijepalli;Andrew J. Lokuta;Nathan A. Maertz;Jennifer M. Buck

  • Modulation of Cardiac Ryanodine Receptors by Sorcin

    Andrew J. Lokuta;Marian B. Meyers;Paul R. Sander;Glenn I. Fishman

  • Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle

    H H Valdivia;M S Kirby;W J Lederer;R Coronado

  • Increased Nitration of Sarcoplasmic Reticulum Ca2+-ATPase in Human Heart Failure

    Andrew J. Lokuta;Nathan A. Maertz;Sivan Vadakkadath Meethal;Katherine T. Potter

  • Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm

    Marina Cerrone;Jerome Montnach;Xianming Lin;Yan Ting Zhao

  • Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart.

    Emily F. Farrell;Anaid Antaramian;Angelica Rueda;Ana M. Gómez

  • Intact β-Adrenergic Response and Unmodified Progression Toward Heart Failure in Mice With Genetic Ablation of a Major Protein Kinase A Phosphorylation Site in the Cardiac Ryanodine Receptor

    Nancy A. Benkusky;Craig S. Weber;Joseph A. Scherman;Emily F. Farrell

  • The Mechanism of Inhibition of Ryanodine Receptor Channels by Imperatoxin I, a Heterodimeric Protein from the Scorpion Pandinus imperator

    Fernando Z. Zamudio;Renaud Conde;Carolina Arévalo;Baltazar Becerril

  • Hyperphosphorylation of the Cardiac Ryanodine Receptor at Serine 2808 Is Not Involved in Cardiac Dysfunction After Myocardial Infarction

    Hongyu Zhang;Catherine A. Makarewich;Hajime Kubo;Wei Wang

  • Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca(2+) homeostasis.

    Jinhua Shen;Wen Mei Yu;Marco Brotto;Joseph A. Scherman

Frequent Co-Authors

Lourival D. Possani
Lourival D. Possani National Autonomous University of Mexico
Richard L. Moss
Richard L. Moss University of Wisconsin–Madison
José Jalife
José Jalife University of Michigan–Ann Arbor
Timothy J. Kamp
Timothy J. Kamp University of Wisconsin–Madison
W. J. Lederer
W. J. Lederer University of Maryland, Baltimore
Heping Cheng
Heping Cheng Peking University
Donald M. Bers
Donald M. Bers University of California, Davis
Xander H.T. Wehrens
Xander H.T. Wehrens Baylor College of Medicine
Clara Franzini-Armstrong
Clara Franzini-Armstrong University of Pennsylvania

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