World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9942
World Ranking
13389
National Ranking
373

Overview

Angela F. Dulhunty is affiliated with the Australian National University in Australia. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a strong intersection in medicine. The main areas of study include molecular biology, cardiology and cardiovascular medicine, genetics, physiology, and cellular and molecular neuroscience.

The scientist's work covers several topics related to cardiac function and molecular regulation, including:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Cardiac arrhythmias and treatments
  • Cardiovascular effects of exercise
  • Neutrophil, myeloperoxidase, and oxidative mechanisms
  • Blood disorders and treatments
  • Nitric oxide and endothelin effects

Recent publications provide insight into their research focus and contributions. These include:

  • "Neutralizing the pathological effects of extracellular histones with small polyanions," 2020, Nature Communications
  • "How does flecainide impact RyR2 channel function?" 2022, The Journal of General Physiology
  • "Flecainide Paradoxically Activates Cardiac Ryanodine Receptor Channels under Low Activity Conditions: A Potential Pro-Arrhythmic Action," 2021, Cells
  • "Molecular Changes in the Cardiac RyR2 With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)," 2022, Frontiers in Physiology
  • "FKBP12 binds to the cardiac ryanodine receptor with negative cooperativity: implications for heart muscle physiology in health and disease," 2023, Philosophical Transactions of the Royal Society B Biological Sciences

Angela F. Dulhunty has frequently collaborated with several researchers, indicating a network of scientific interaction. Notable coauthors include:

  • Samantha C. Salvage (5 collaborations)
  • Christopher Huang (5 collaborations)
  • James A. Fraser (4 collaborations)
  • Chris Thekkedam (4 collaborations)
  • Marco G. Casarotto (4 collaborations)

Their research is regularly published in several scientific venues, with multiple contributions in:

  • Nature Communications
  • The Journal of General Physiology
  • Philosophical Transactions of the Royal Society B Biological Sciences
  • Cells
  • International Journal of Molecular Sciences

Best Publications

  • Calsequestrin and the calcium release channel of skeletal and cardiac muscle

    Nicole Beard;Derek Rowland Laver;Angela Dulhunty

  • The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator.

    Angela Dulhunty;Peter Gage;Suzanne Curtis;Gareth Chelvanayagam

  • Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1

    Takashi Kimura;Masayuki Nakamori;John D. Lueck;Pierre Pouliquin

  • The relative contributions of the folds and caveolae to the surface membrane of frog skeletal muscle fibres at different sarcomere lengths.

    A F Dulhunty;C Franzini-Armstrong

  • Low resistance junctions in crayfish. Structural changes with functional uncoupling.

    C Peracchia;A F Dulhunty

  • Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanisms.

    D R Laver;T M Baynes;A F Dulhunty

  • Calsequestrin Is an Inhibitor of Skeletal Muscle Ryanodine Receptor Calcium Release Channels

    Nicole A. Beard;Magdalena M. Sakowska;Angela F. Dulhunty;Derek R. Laver

  • Excitation-contraction coupling from the 1950s into the new millennium.

    Angela Dulhunty

  • Cytoplasmic Ca2+ inhibits the ryanodine receptor from cardiac muscle.

    D. R. Laver;L. D. Roden;G. P. Ahern;K. R. Eager

  • Paralysis of skeletal muscle by butanedione monoxime, a chemical phosphatase

    M. W. Fryer;P. W. Gage;I. R. Neering;A. F. Dulhunty

  • Single channel activity of the ryanodine receptor calcium release channel is modulated by FK-506

    Gerard P. Ahern;Pauline R. Junankar;Angela F. Dulhunty

  • Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12.

    G.P. Ahern;P.R. Junankar;A.F. Dulhunty

  • The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling

    Gerard Mark Gibbs;Martin J Scanlon;James David Swarbrick;Suzanne Curtis

  • Adverse effects of doxorubicin and its metabolic product on cardiac RyR2 and SERCA2A.

    Amy D. Hanna;Alex Lam;Steffi Tham;Angela F. Dulhunty

  • Regulation of Ryanodine Receptors by Calsequestrin: Effect of High Luminal Ca2+ and Phosphorylation

    Nicole A. Beard;Marco G. Casarotto;Lan Wei;Magdolna Varsányi

  • Skeletal muscle excitation–contraction coupling: Who are the dancing partners?

    Robyn T. Rebbeck;Yamuna Karunasekara;Philip G. Board;Nicole A. Beard

  • Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.

    D.R. Laver;V.J. Owen;P.R. Junankar;N.L. Taske

  • Distribution of potassium and chloride permeability over the surface and T-tubule membranes of mammalian skeletal muscle.

    Angela F. Dulhunty

  • Nitric oxide activates or inhibits skeletal muscle ryanodine receptors depending on its concentration, membrane potential and ligand binding.

    James Hart;Angela Dulhunty

  • The dependence of membrane potential on extracellular chloride concentration in mammalian skeletal muscle fibres.

    A F Dulhunty

Frequent Co-Authors

Philip G. Board
Philip G. Board Australian National University
Peter W. Gage
Peter W. Gage Australian National University
Robert T. Dirksen
Robert T. Dirksen University of Rochester
Graham D. Lamb
Graham D. Lamb La Trobe University
Peter C. M. Molenaar
Peter C. M. Molenaar Pennsylvania State University
Peter H. Barry
Peter H. Barry University of New South Wales
Charles E. Schwartz
Charles E. Schwartz Greenwood Genetic Center
Jeremy Mould
Jeremy Mould Swinburne University of Technology
Clara Franzini-Armstrong
Clara Franzini-Armstrong University of Pennsylvania
Istvan Toth
Istvan Toth University of Queensland

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