Robert T. Dirksen

Overview

Best Publications

• Superoxide Flashes in Single Mitochondria

  Wang Wang;Huaqiang Fang;Linda Groom;Aiwu Cheng

  778
  Citations

• Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor.

  Junichi Nakai;Junichi Nakai;Robert T. Dirksen;Hanh T. Nguyen;Isaac N. Pessah

  525
  Citations

• Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

  Thurman M. Wheeler;Krzysztof Sobczak;John D. Lueck;Robert J. Osborne

  429
  Citations

• RyR1 S-Nitrosylation Underlies Environmental Heat Stroke and Sudden Death in Y522S RyR1 Knockin Mice

  William J. Durham;Paula Aracena-Parks;Cheng Long;Ann E. Rossi

  365
  Citations

• Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

  Thurman M. Wheeler;John D. Lueck;Maurice S. Swanson;Robert T. Dirksen

  306
  Citations

• Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1

  Takashi Kimura;Masayuki Nakamori;John D. Lueck;Pierre Pouliquin

  302
  Citations

• Mitochondria Are Linked to Calcium Stores in Striated Muscle by Developmentally Regulated Tethering Structures

  Simona Boncompagni;Ann E. Rossi;Massimo Micaroni;Galina V. Beznoussenko

  288
  Citations

• Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain

  Yoshihiko Fujita;Michelle Mynlieff;Robert T. Dirksen;Man Suk Kim

  280
  Citations

• Identification of Cysteines Involved in S-Nitrosylation, S-Glutathionylation, and Oxidation to Disulfides in Ryanodine Receptor Type 1

  Paula Aracena-Parks;Sanjeewa A. Goonasekera;Charles P. Gilman;Robert T. Dirksen

  271
  Citations

• Epac and Phospholipase Cϵ Regulate Ca2+ Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II

  Emily A. Oestreich;Sundeep Malik;Sanjeewa A. Goonasekera;Burns C. Blaxall

  246
  Citations

• The II-III Loop of the Skeletal Muscle Dihydropyridine Receptor Is Responsible for the Bi-directional Coupling with the Ryanodine Receptor

  Manfred Grabner;Robert T. Dirksen;Norio Suda;Kurt G. Beam

  236
  Citations

• Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes.

  Emily A. Oestreich;Huan Wang;Sundeep Malik;Katherine A. Kaproth-Joslin

  226
  Citations

• Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy

  Prince J. Kannankeril;Brett M. Mitchell;Sanjeewa A. Goonasekera;Mihail G. Chelu

  222
  Citations

• Differential dependence of store-operated and excitation-coupled Ca2+ entry in skeletal muscle on STIM1 and Orai1

  Alla D. Lyfenko;Robert T. Dirksen

  215
  Citations

• Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse

  Mihail G. Chelu;Sanjeewa A. Goonasekera;William J. Durham;Wei Tang

  202
  Citations

• Identical De Novo Mutation in the Type 1 Ryanodine Receptor Gene Associated With Fatal, Stress-Induced Malignant Hyperthermia in Two Unrelated Families

  Linda Groom;Sheila M. Muldoon;Zhen Zhi Tang;Barbara W. Brandom

  198
  Citations

• Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of CaV1.1 calcium channel

  Zhen Zhi Tang;Viktor Yarotskyy;Lan Wei;Krzysztof Sobczak

  190
  Citations

• Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling.

  Gisela Beutner;Virendra K. Sharma;Lin Lin;Shin-Young Ryu

  187
  Citations

• Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes

  Manfred Grabner;Robert T. Dirksen;Kurt G. Beam

  174
  Citations

• Checking your SOCCs and feet: the molecular mechanisms of Ca2+ entry in skeletal muscle.

  Robert T. Dirksen

  167
  Citations