World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11970
World Ranking
10942
National Ranking
4735

Research.com Recognitions

  • 2012 - Member of the National Academy of Sciences

Overview

Kurt G. Beam is affiliated with the University of Colorado Denver in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, Sensory Systems, and Atomic and Molecular Physics, and Optics.

The key research topics explored by Kurt G. Beam include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic Acetylcholine Receptors Study
  • Ion Channels and Receptors
  • Toxin Mechanisms and Immunotoxins
  • Pain Mechanisms and Treatments
  • Receptor Mechanisms and Signaling

Frequent publication venues for Beam's work feature:

  • Biophysical Journal (6 publications)
  • The Journal of General Physiology (3 publications)
  • Journal of Biological Chemistry (2 publications)
  • eLife (1 publication)
  • Proceedings of the National Academy of Sciences (1 publication)

Notable recent papers include:

  • Neuronal junctophilins recruit specific CaV and RyR isoforms to ER-PM junctions and functionally alter CaV2.1 and CaV2.2, 2021, eLife
  • Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence, 2022, The Journal of General Physiology
  • The funny current If is essential for the fight-or-flight response in cardiac pacemaker cells, 2022, The Journal of General Physiology
  • Voltage-induced Ca2+ release is supported by junctophilins 1, 2 and 3, and not by junctophilin 4, 2021, The Journal of General Physiology
  • The distal C terminus of the dihydropyridine receptor β1asubunit is essential for tetrad formation in skeletal muscle, 2022, Proceedings of the National Academy of Sciences

Beam has collaborated frequently with researchers including Stefano Perni, Colin H. Peters, Catherine Proenza, Danielle M. Heebner, and Alexander Polster.

An award recognized in Beam's career is election as a Member of the National Academy of Sciences in 2012.

Best Publications

  • Restoration of excitation—contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA

    Tsutomu Tanabe;Kurt G. Beam;Jeanne A. Powell;Shosaku Numa

  • Regions of the skeletal muscle dihydropyridine receptor critical for excitation-contraction coupling.

    Tsutomu Tanabe;Kurt G. Beam;Brett A. Adams;Tetsuhiro Niidome

  • Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor.

    Junichi Nakai;Junichi Nakai;Robert T. Dirksen;Hanh T. Nguyen;Isaac N. Pessah

  • Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs.

    Brett A. Adams;Tsutomu Tanabe;Atsushi Mikami;Shosaku Numa

  • A lethal mutation in mice eliminates the slow calcium current in skeletal muscle cells.

    Beam Kg;Knudson Cm;Powell Ja

  • Cardiac-type excitation-contraction coupling in dysgenic skeletal muscle injected with cardiac dihydropyridine receptor cDNA

    Tsutomu Tanabe;Atsushi Mikami;Shosaku Numa;Kurt G. Beam

  • Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain

    Yoshihiko Fujita;Michelle Mynlieff;Robert T. Dirksen;Man Suk Kim

  • Apical localization of K+ channels in taste cells provides the basis for sour taste transduction.

    Sue C. Kinnamon;Vincent E. Dionne;Kurt G. Beam

  • Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels.

    Junichi Nakai;Naomi Sekiguchi;Thomas A. Rando;Paul D. Allen

  • The II-III Loop of the Skeletal Muscle Dihydropyridine Receptor Is Responsible for the Bi-directional Coupling with the Ryanodine Receptor

    Manfred Grabner;Robert T. Dirksen;Norio Suda;Kurt G. Beam

  • The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins.

    Katarina Stroffekova;Catherine Proenza;Kurt G. Beam

  • Triclosan impairs excitation–contraction coupling and Ca2+ dynamics in striated muscle

    Gennady Cherednichenko;Rui Zhang;Roger A. Bannister;Valeriy Timofeyev

  • Localization in the II-III Loop of the Dihydropyridine Receptor of a Sequence Critical for Excitation-Contraction Coupling

    Junichi Nakai;Tsutomu Tanabe;Takashi Konno;Brett Adams

  • Calcium currents in embryonic and neonatal mammalian skeletal muscle.

    K G Beam;C M Knudson

  • Altered Calcium Channel Currents in Purkinje Cells of the Neurological Mutant Mouse leaner

    Nancy M. Lorenzon;Cathleen M. Lutz;Wayne N. Frankel;Kurt G. Beam

  • Development Alters the Expression of Calcium Currents in Chick - limb Motoneurons

    David P. McCobb;Phillip M. Best;Kurt G. Beam

  • Action potential waveform voltage-clamp commands reveal striking differences in calcium entry via low and high voltage-activated calcium channels.

    David P. McCobb;Kurt G. Beam

  • Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics

    Tsutomu Tanabe;Brett A. Adams;Shosaku Numa;Kurt G. Beam

  • Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes

    Manfred Grabner;Robert T. Dirksen;Kurt G. Beam

  • Specific Absence of the α1 Subunit of the Dihydropyridine Receptor in Mice with Muscular Dysgenesis

    C. M. Knudson;Nirupa Chaudhari;A. H. Sharp;J. A. Powell

Frequent Co-Authors

Paul D. Allen
Paul D. Allen St James's University Hospital
Isaac N. Pessah
Isaac N. Pessah University of California, Davis
Robert T. Dirksen
Robert T. Dirksen University of Rochester
Shosaku Numa
Shosaku Numa Kyoto University
Clara Franzini-Armstrong
Clara Franzini-Armstrong University of Pennsylvania
Keiji Imoto
Keiji Imoto National Institute for Physiological Sciences
Eric N. Olson
Eric N. Olson The University of Texas Southwestern Medical Center
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Sue C. Kinnamon
Sue C. Kinnamon University of Colorado Anschutz Medical Campus
Takashi Miyata
Takashi Miyata Kyoto University

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