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2026

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Best Scientists

D-Index
207
Citations
167417
World Ranking
227
National Ranking
150

Neuroscience

D-Index
211
Citations
173063
World Ranking
21
National Ranking
15

Medicine

D-Index
211
Citations
173608
World Ranking
131
National Ranking
88

Research.com Recognitions

  • 2026 - Research.com Medicine in United States Leader Award
  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award
  • 2022 - Research.com Neuroscience in United States Leader Award
  • 2010 - Rhoda and Bernard Sarnat International Prize in Mental Health, National Academy of Medicine
  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1998 - Member of the National Academy of Medicine (NAM)
  • 1997 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Eric J. Nestler is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research focuses primarily on neuroscience and biochemistry, genetics, and molecular biology. With over 200 publications in neuroscience and more than 130 in biochemistry and molecular biology, their work spans multiple subfields including molecular biology, cellular and molecular neuroscience, behavioral neuroscience, biological psychiatry, and physiology.

Their scientific contributions encompass several key topics, including:

  • Stress Responses and Cortisol
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Tryptophan and Brain Disorders
  • Epigenetics and DNA Methylation
  • Neuroendocrine Regulation and Behavior

Frequent publication venues for Eric J. Nestler include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biological Psychiatry
  • Trends in Neurosciences
  • Science Advances
  • Molecular Psychiatry

Notable recent papers by Eric J. Nestler include:

  • "Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation" (2020, Journal of Medical Internet Research)
  • "Midbrain projection to the basolateral amygdala encodes anxiety-like but not depression-like behaviors" (2022, Nature Communications)
  • "Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression" (2020, Neuron)
  • "Viral tools for neuroscience" (2020, Nature reviews. Neuroscience)
  • "Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice" (2020, Nature Neuroscience)

Frequent co-authors include:

  • Li Shen
  • Eric M. Parise
  • Caleb J. Browne
  • Scott J. Russo
  • Aarthi Ramakrishnan

Eric J. Nestler has contributed to book publications, including a title published by McGraw-Hill eBooks: "Nestler, Hyman & Malenka's molecular neuropharmacology: a foundation for clinical neuroscience" (2020).

Throughout their career, they have been recognized with several awards, such as:

  • Rhoda and Bernard Sarnat International Prize in Mental Health, National Academy of Medicine (2010)
  • Fellow of the American Academy of Arts and Sciences (2005)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2003)
  • Member of the National Academy of Medicine (NAM) (1998)
  • Robert J. and Claire Pasarow Foundation Medical Research Award (1997)
  • Fellow of Alfred P. Sloan Foundation (1987)

Best Publications

  • Neurobiology of depression.

    Eric J. Nestler;Michel Barrot;Ralph J. DiLeone;Amelia J. Eisch

  • Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

    Jessica E. Malberg;Amelia J. Eisch;Eric J. Nestler;Ronald S. Duman

  • The molecular neurobiology of depression

    Vaishnav Krishnan;Eric J. Nestler;Eric J. Nestler

  • NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory

    Steven E. Hyman;Robert C. Malenka;Eric J. Nestler

  • A molecular and cellular theory of depression

    Ronald S. Duman;George R. Heninger;Eric J. Nestler

  • Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

    Vaishnav Krishnan;Ming Hu Han;Danielle L. Graham;Olivier Berton

  • Molecular basis of long-term plasticity underlying addiction

    Eric J. Nestler

  • Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress

    Olivier Berton;Colleen A. McClung;Ralph J. DiLeone;Vaishnav Krishnan

  • The Mesolimbic Dopamine Reward Circuit in Depression

    Eric J. Nestler;William A. Carlezon

  • Animal models of neuropsychiatric disorders

    Eric J Nestler;Steven E Hyman

  • The brain reward circuitry in mood disorders

    Scott J. Russo;Eric J. Nestler

  • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

    Nadia M Tsankova;Olivier Berton;William Renthal;Arvind Kumar

  • New approaches to antidepressant drug discovery: beyond monoamines

    Olivier Berton;Eric J. Nestler

  • Molecular and Cellular Basis of Addiction

    Eric J. Nestler;George K. Aghajanian

  • Is there a common molecular pathway for addiction

    Eric J Nestler

  • Epigenetic regulation in psychiatric disorders

    Nadia Tsankova;William Renthal;Arvind Kumar;Eric J. Nestler

  • Molecular mechanisms of drug addiction

    Eric J. Nestler

  • Psychobiology and molecular genetics of resilience.

    Adriana Feder;Eric J. Nestler;Dennis S. Charney

  • The many faces of CREB

    William A. Carlezon;Ronald S. Duman;Eric J. Nestler

  • CHRONIC ANTIDEPRESSANT ADMINISTRATION INCREASES THE EXPRESSION OF CAMP RESPONSE ELEMENT BINDING PROTEIN (CREB) IN RAT HIPPOCAMPUS

    M Nibuya;EJ Nestler;RS Duman

Frequent Co-Authors

Rachael L. Neve
Rachael L. Neve Harvard University
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai
Ronald S. Duman
Ronald S. Duman Yale University
Li Shen
Li Shen Icahn School of Medicine at Mount Sinai
Vincent Vialou
Vincent Vialou Sorbonne University
Ming-Hu Han
Ming-Hu Han Icahn School of Medicine at Mount Sinai
David M. Dietz
David M. Dietz University at Buffalo, State University of New York
Jian Feng
Jian Feng University at Buffalo, State University of New York
David W. Self
David W. Self The University of Texas Southwestern Medical Center
Michel Barrot
Michel Barrot Centre national de la recherche scientifique, CNRS

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