D-Index & Metrics Best Publications
Biology and Biochemistry
USA
2023
Neuroscience
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 188 Citations 112,352 751 World Ranking 18 National Ranking 12
Biology and Biochemistry D-index 207 Citations 134,796 875 World Ranking 17 National Ranking 15

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in United States Leader Award

2023 - Research.com Neuroscience in United States Leader Award

2004 - Fellow of the American Association for the Advancement of Science (AAAS)

2000 - Nobel Prize for their discoveries concerning signal transduction in the nervous system

1999 - Member of the National Academy of Medicine (NAM)

1998 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

1994 - Ralph W. Gerard Prize in Neuroscience, Society for Neuroscience

1993 - Karl Spencer Lashley Award, The American Philosophical Society For his pioneering work on the molecular basis of signal transduction and vesicle mobilization in nerve cells

1991 - NAS Award in the Neurosciences, U.S. National Academy of Sciences For his discovery of the central role played by neuronal phosphoproteins in normal brain function as well as in neuropsychiatric and related disorders.

1978 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Neuron

His main research concerns Cell biology, Neuroscience, Biochemistry, Internal medicine and Endocrinology. His Cell biology research integrates issues from Synapsin, Synapsin I, Synaptic vesicle, AMPA receptor and Molecular biology. His study looks at the relationship between Neuroscience and fields such as Synaptic plasticity, as well as how they intersect with chemical problems.

His Biochemistry study frequently draws connections between adjacent fields such as Amyloid precursor protein. His Endocrinology research incorporates elements of Apical membrane, Chloride channel, Na+/K+-ATPase and Membrane potential. His study in Phosphorylation is interdisciplinary in nature, drawing from both Signal transduction and Cytoskeleton.

His most cited work include:

  • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor (1935 citations)
  • Regulation of NMDA receptor trafficking by amyloid-beta. (1264 citations)
  • Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function (1126 citations)

What are the main themes of his work throughout his whole career to date?

Paul Greengard mostly deals with Cell biology, Neuroscience, Biochemistry, Phosphorylation and Protein kinase A. His Cell biology study incorporates themes from Synapsin, Synapsin I and Synaptic vesicle. As a part of the same scientific family, Paul Greengard mostly works in the field of Synapsin I, focusing on Neurotransmitter and, on occasion, Neurotransmission.

His biological study deals with issues like Synaptic plasticity, which deal with fields such as Long-term potentiation. His Amyloid precursor protein research extends to the thematically linked field of Biochemistry. Paul Greengard has researched Protein kinase A in several fields, including Substantia nigra and Molecular biology.

He most often published in these fields:

  • Cell biology (31.23%)
  • Neuroscience (27.91%)
  • Biochemistry (25.25%)

What were the highlights of his more recent work (between 2013-2021)?

  • Neuroscience (27.91%)
  • Cell biology (31.23%)
  • Antidepressant (3.65%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Neuroscience, Cell biology, Antidepressant, Dopamine and Medium spiny neuron. His research investigates the connection between Neuroscience and topics such as Dyskinesia that intersect with problems in Direct pathway of movement, Levodopa and Parkinsonism. He is interested in Phosphorylation, which is a branch of Cell biology.

His study on Antidepressant also encompasses disciplines like

  • Serotonin that intertwine with fields like Premovement neuronal activity,
  • Molecular biology most often made with reference to Cell type,
  • 5-HT receptor which connect with Biological neural network. His work in Dopamine addresses issues such as Pharmacology, which are connected to fields such as Cholinergic. Paul Greengard has included themes like Signal transduction and Protein kinase A in his Medium spiny neuron study.

Between 2013 and 2021, his most popular works were:

  • Cell type–specific mRNA purification by translating ribosome affinity purification (TRAP) (231 citations)
  • Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia (168 citations)
  • M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia (125 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Neuron

Paul Greengard mainly investigates Neuroscience, Cell biology, Antidepressant, Dentate gyrus and Phosphorylation. Many of his studies on Neuroscience apply to Signal transduction as well. His studies deal with areas such as Single-cell analysis, Molecular biology, Presenilin, Polysome and Cell sorting as well as Cell biology.

His Phosphorylation research is classified as research in Biochemistry. His study focuses on the intersection of Biochemistry and fields such as Environmental enrichment with connections in the field of Protein kinase A and Dendritic spine. His work in Long-term potentiation addresses subjects such as Neurotrophic factors, which are connected to disciplines such as Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Noboru Sato;Laurent Meijer;Laurent Meijer;Leandros Skaltsounis;Paul Greengard.
Nature Medicine (2004)

2528 Citations

Regulation of NMDA receptor trafficking by amyloid-beta.

Eric M Snyder;Yi Nong;Claudia G Almeida;Surojit Paul.
Nature Neuroscience (2005)

1828 Citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

Paul Greengard;Flavia Valtorta;Andrew J. Czernik;Fabio Benfenati.
Science (1993)

1526 Citations

Intraneuronal Aβ42 Accumulation in Human Brain

Gunnar K. Gouras;Gunnar K. Gouras;Julia Tsai;Jan Naslund;Bruno Vincent.
American Journal of Pathology (2000)

1218 Citations

The neurobiology of slow synaptic transmission.

Paul Greengard.
Science (2001)

1165 Citations

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

Weixing Shen;Marc Flajolet;Paul Greengard;D. James Surmeier.
Science (2008)

1114 Citations

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.

Jonathan Goldberg;Hsien Bin Huang;Young Guen Kwon;Paul Greengard.
Nature (1995)

1076 Citations

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

Myriam Heiman;Anne Schaefer;Shiaoching Gong;Jayms D. Peterson.
Cell (2008)

1052 Citations

Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease A PROPERTY COMMON TO MOST CYCLIN-DEPENDENT KINASE INHIBITORS?

Sophie Leclerc;Matthieu Garnier;Ralph Hoessel;Doris Marko.
Journal of Biological Chemistry (2001)

1021 Citations

Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.

Paul Greengard;Patrick B. Allen;Angus C. Nairn.
Neuron (1999)

947 Citations

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