D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 66 Citations 14,950 157 World Ranking 1042 National Ranking 31
Biology and Biochemistry D-index 79 Citations 20,391 205 World Ranking 1835 National Ranking 31

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Neuron

Jean-Antoine Girault mostly deals with Dopamine, Cell biology, Endocrinology, Internal medicine and Signal transduction. Jean-Antoine Girault studies Dopamine, namely Striatum. He has included themes like Substantia nigra, Basal ganglia, Adenylyl cyclase and MAPK/ERK pathway in his Striatum study.

His studies deal with areas such as Synaptic plasticity, Nucleus accumbens and Neuroscience as well as MAPK/ERK pathway. His work deals with themes such as Paranodal junction, Histone H3, Biochemistry and Nervous system, which intersect with Cell biology. Jean-Antoine Girault combines subjects such as Phosphatase and Phosphorylation with his study of Signal transduction.

His most cited work include:

  • DARPP-32: an integrator of neurotransmission. (552 citations)
  • Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum (519 citations)
  • Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons (505 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Neuroscience, Dopamine, Phosphorylation and Striatum. His Biochemistry research extends to the thematically linked field of Cell biology. As part of his studies on Neuroscience, Jean-Antoine Girault often connects relevant subjects like Synaptic plasticity.

Internal medicine and Endocrinology are the subject areas of his Dopamine study. His Phosphorylation study combines topics from a wide range of disciplines, such as Signal transduction and Kinase. His studies examine the connections between Striatum and genetics, as well as such issues in MAPK/ERK pathway, with regards to Pharmacology and Glutamate receptor.

He most often published in these fields:

  • Cell biology (55.63%)
  • Neuroscience (49.20%)
  • Dopamine (48.55%)

What were the highlights of his more recent work (between 2017-2021)?

  • Neuroscience (49.20%)
  • Striatum (37.62%)
  • Dopamine (48.55%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Neuroscience, Striatum, Dopamine, Nucleus accumbens and Hippocampus. His studies in Neuroscience integrate themes in fields like Synaptic plasticity, Long-term potentiation and Knockout mouse. His Striatum research is multidisciplinary, relying on both Local field potential and Transgene.

Jean-Antoine Girault interconnects Dentate gyrus, Immediate early gene and Cell biology in the investigation of issues within Transgene. His study on Dopamine receptor D1 is often connected to Amplitude of low frequency fluctuations as part of broader study in Dopamine. His Dopamine receptor D1 study frequently draws connections between adjacent fields such as Signal transduction.

Between 2017 and 2021, his most popular works were:

  • Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease (50 citations)
  • Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease (50 citations)
  • PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease (19 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Neuron

Jean-Antoine Girault mainly investigates Neuroscience, Dopamine, Knockout mouse, Dendritic spine and Nucleus accumbens. The concepts of his Neuroscience study are interwoven with issues in Protein kinase R and Neurodegeneration. He integrates Dopamine and Melanocortins in his research.

His Knockout mouse study combines topics in areas such as Forebrain, Anhedonia, NMDA receptor, Major depressive disorder and Chronic stress. His work carried out in the field of Nucleus accumbens brings together such families of science as Amphetamine, Striatum, Dopamine receptor D2 and Transgene. His Striatum research incorporates themes from Functional magnetic resonance imaging, Local field potential, Cortex and Premovement neuronal activity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

DARPP-32: an integrator of neurotransmission.

Per Svenningsson;Akinori Nishi;Gilberto Fisone;Jean-Antoine Girault.
Annual Review of Pharmacology and Toxicology (2004)

725 Citations

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

Emmanuel Valjent;Vincent Pascoli;Per Svenningsson;Surojit Paul.
Proceedings of the National Academy of Sciences of the United States of America (2005)

657 Citations

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

James A. Bibb;Gretchen L. Snyder;Akinori Nishi;Zhen Yan.
Nature (1999)

618 Citations

Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.

Emmanuel Valjent;Christiane Pagès;Denis Hervé;Jean-Antoine Girault.
European Journal of Neuroscience (2004)

593 Citations

Protein interaction mapping: A Drosophila case study

Etienne Formstecher;Sandra Aresta;Vincent Collura;Alexandre Hamburger.
Genome Research (2005)

586 Citations

Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol.

Jesus Bertran-Gonzalez;Clémentine Bosch;Matthieu Maroteaux;Miriam Matamales.
The Journal of Neuroscience (2008)

568 Citations

DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission

A. A. Fienberg;N. Hiroi;Paul G Mermelstein;W. J. Song.
Science (1998)

553 Citations

The Neurobiology of Dopamine Signaling

Jean-Antoine Girault;Paul Greengard.
JAMA Neurology (2004)

533 Citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.

Shelley Halpain;Jean-Antoine Girault;Jean-Antoine Girault;Paul Greengard.
Nature (1990)

506 Citations

ERK2: a logical AND gate critical for drug-induced plasticity?

Jean-Antoine Girault;Emmanuel Valjent;Emmanuel Valjent;Jocelyne Caboche;Jocelyne Caboche;Denis Hervé;Denis Hervé.
Current Opinion in Pharmacology (2007)

454 Citations

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