Jean-Antoine Girault mostly deals with Dopamine, Cell biology, Endocrinology, Internal medicine and Signal transduction. Jean-Antoine Girault studies Dopamine, namely Striatum. He has included themes like Substantia nigra, Basal ganglia, Adenylyl cyclase and MAPK/ERK pathway in his Striatum study.
His studies deal with areas such as Synaptic plasticity, Nucleus accumbens and Neuroscience as well as MAPK/ERK pathway. His work deals with themes such as Paranodal junction, Histone H3, Biochemistry and Nervous system, which intersect with Cell biology. Jean-Antoine Girault combines subjects such as Phosphatase and Phosphorylation with his study of Signal transduction.
The scientist’s investigation covers issues in Cell biology, Neuroscience, Dopamine, Phosphorylation and Striatum. His Biochemistry research extends to the thematically linked field of Cell biology. As part of his studies on Neuroscience, Jean-Antoine Girault often connects relevant subjects like Synaptic plasticity.
Internal medicine and Endocrinology are the subject areas of his Dopamine study. His Phosphorylation study combines topics from a wide range of disciplines, such as Signal transduction and Kinase. His studies examine the connections between Striatum and genetics, as well as such issues in MAPK/ERK pathway, with regards to Pharmacology and Glutamate receptor.
His scientific interests lie mostly in Neuroscience, Striatum, Dopamine, Nucleus accumbens and Hippocampus. His studies in Neuroscience integrate themes in fields like Synaptic plasticity, Long-term potentiation and Knockout mouse. His Striatum research is multidisciplinary, relying on both Local field potential and Transgene.
Jean-Antoine Girault interconnects Dentate gyrus, Immediate early gene and Cell biology in the investigation of issues within Transgene. His study on Dopamine receptor D1 is often connected to Amplitude of low frequency fluctuations as part of broader study in Dopamine. His Dopamine receptor D1 study frequently draws connections between adjacent fields such as Signal transduction.
Jean-Antoine Girault mainly investigates Neuroscience, Dopamine, Knockout mouse, Dendritic spine and Nucleus accumbens. The concepts of his Neuroscience study are interwoven with issues in Protein kinase R and Neurodegeneration. He integrates Dopamine and Melanocortins in his research.
His Knockout mouse study combines topics in areas such as Forebrain, Anhedonia, NMDA receptor, Major depressive disorder and Chronic stress. His work carried out in the field of Nucleus accumbens brings together such families of science as Amphetamine, Striatum, Dopamine receptor D2 and Transgene. His Striatum research incorporates themes from Functional magnetic resonance imaging, Local field potential, Cortex and Premovement neuronal activity.
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DARPP-32: an integrator of neurotransmission.
Per Svenningsson;Akinori Nishi;Gilberto Fisone;Jean-Antoine Girault.
Annual Review of Pharmacology and Toxicology (2004)
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
Emmanuel Valjent;Vincent Pascoli;Per Svenningsson;Surojit Paul.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
James A. Bibb;Gretchen L. Snyder;Akinori Nishi;Zhen Yan.
Nature (1999)
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
Emmanuel Valjent;Christiane Pagès;Denis Hervé;Jean-Antoine Girault.
European Journal of Neuroscience (2004)
Protein interaction mapping: A Drosophila case study
Etienne Formstecher;Sandra Aresta;Vincent Collura;Alexandre Hamburger.
Genome Research (2005)
Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol.
Jesus Bertran-Gonzalez;Clémentine Bosch;Matthieu Maroteaux;Miriam Matamales.
The Journal of Neuroscience (2008)
DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission
A. A. Fienberg;N. Hiroi;Paul G Mermelstein;W. J. Song.
Science (1998)
The Neurobiology of Dopamine Signaling
Jean-Antoine Girault;Paul Greengard.
JAMA Neurology (2004)
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Shelley Halpain;Jean-Antoine Girault;Jean-Antoine Girault;Paul Greengard.
Nature (1990)
ERK2: a logical AND gate critical for drug-induced plasticity?
Jean-Antoine Girault;Emmanuel Valjent;Emmanuel Valjent;Jocelyne Caboche;Jocelyne Caboche;Denis Hervé;Denis Hervé.
Current Opinion in Pharmacology (2007)
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Publications: 32
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