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Susan R. George

Susan R. George

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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
27926
World Ranking
2335
National Ranking
69

Medicine

D-Index
93
Citations
28608
World Ranking
10972
National Ranking
437

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Susan R. George is affiliated with the University of Toronto in Canada, focusing their research primarily in the field of Medicine with a notable contribution to several subfields including Cellular and Molecular Neuroscience, Epidemiology, Molecular Biology, Pharmacology, and Hepatology.

Their research spans a range of topics, with particular attention to areas such as:

  • Liver Disease Diagnosis and Treatment
  • Cannabis and Cannabinoid Research
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Receptor Mechanisms and Signaling
  • Diet, Metabolism, and Disease

Susan R. George's recent publications reflect a focus on the molecular and behavioral aspects of neuropsychiatric disorders, depression, anxiety, and related receptor mechanisms. Selected recent papers include:

  • "Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors" (2020), published in Biology of Sex Differences
  • "Sex Differences in Dopamine Receptors and Relevance to Neuropsychiatric Disorders" (2021), published in Brain Sciences
  • "Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review" (2023), published in Brain Sciences
  • "Dopamine D1-D2 receptor heteromer expression in key brain regions of rat and higher species: Upregulation in rat striatum after cocaine administration" (2020), published in Neurobiology of Disease
  • "22q11.2 microdeletion and increased risk for type 2 diabetes" (2020), published in EClinicalMedicine

The most frequent publication venues for their research include:

  • Journal of Clinical and Experimental Hepatology
  • Brain Sciences
  • Drug and Alcohol Dependence
  • JACC. Cardiovascular Imaging
  • Journal of Pharmaceutical Sciences

Collaborations form a significant part of Susan R. George's work, with several frequent co-authors contributing across multiple publications. Notable frequent co-authors include:

  • Krishnadas Devadas
  • Ahmed Hasbi
  • Antony George
  • Bertha K. Madras
  • S. Srijaya

The profile of Susan R. George reflects a detailed engagement with biomedical sciences, emphasizing connections between receptor mechanisms, behavioral neuroscience, and clinical impacts in hepatology and metabolic disorders.

Best Publications

  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

    R. K. Sunahara;Hong-Chang Guan;B. F. O'dowd;P. Seeman

  • A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

    Brian F. O'Dowd;Michael Heiber;Audrey Chan;Henry H.Q. Heng

  • Characterization of Apelin, the Ligand for the APJ Receptor

    Dennis K. Lee;Regina Cheng;Tuan Nguyen;Theresa Fan

  • G-Protein-coupled receptor oligomerization and its potential for drug discovery

    Susan R. George;Susan R. George;Brian F. O'Dowd;Brian F. O'Dowd;Samuel P. Lee

  • Characterization of the human cysteinyl leukotriene 2 receptor.

    Christopher E. Heise;Brian F. O'Dowd;David J. Figueroa;Nicole Sawyer

  • Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.

    Susan R. George;Susan R. George;Theresa Fan;Zhidong Xie;Roderick Tse

  • D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum.

    Asim J. Rashid;Christopher H. So;Michael M. C. Kong;Teresa Furtak

  • Discovery of a receptor related to the galanin receptors.

    Dennis K Lee;Tuan Nguyen;Gary P O'Neill;Regina Cheng

  • Discovery of a Novel Member of the Histamine Receptor Family

    Tuan Nguyen;David A. Shapiro;Susan R. George;Vincent Setola

  • Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.

    Dong-Soon Im;Christopher E. Heise;Nicolas Ancellin;Brian F. O'Dowd

  • Identification and cloning of three novel human G protein-coupled receptor genes GPR52, ΨGPR53 and GPR55: GPR55 is extensively expressed in human brain

    Marek Sawzdargo;Tuan Nguyen;Dennis K Lee;Kevin R Lynch

  • Building a new conceptual framework for receptor heteromers

    Sergi Ferré;Ruben Baler;Michel Bouvier;Marc G. Caron

  • Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis

    Philip Seeman;David Weinshenker;Remi Quirion;Lalit K. Srivastava

  • Discovery of three novel G-protein-coupled receptor genes

    Brian F. O'Dowd;Tuan Nguyen;Adriano Marchese;Regina Cheng

  • Dopamine D2 Receptor Dimers and Receptor-Blocking Peptides

    Gordon Y.K. Ng;Brian F. O'Dowd;Samuel P. Lee;Hans T. Chung

  • Modification of the Terminal Residue of Apelin-13 Antagonizes Its Hypotensive Action

    Dennis K. Lee;Victor R. Saldivia;Tuan Nguyen;Regina Cheng

  • Identification of Urotensin II as the Endogenous Ligand for the Orphan G-Protein-Coupled Receptor GPR14

    Qingyun Liu;Sheng Shung Pong;Zhizhen Zeng;Qing Zhang

  • A Cluster of Four Novel Human G Protein-Coupled Receptor Genes Occurring in Close Proximity to CD22 Gene on Chromosome 19q13.1

    Marek Sawzdargo;Susan R. George;Tuan Nguyen;Shijie Xu

  • Discovery and mapping of ten novel G protein-coupled receptor genes.

    Dennis K. Lee;Tuan Nguyen;Kevin R. Lynch;Regina Cheng

  • Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth.

    Ahmed Hasbi;Theresa Fan;Mohammad Alijaniaram;Tuan Nguyen

Frequent Co-Authors

Brian F. O'Dowd
Brian F. O'Dowd Centre for Addiction and Mental Health
Tuan V. Nguyen
Tuan V. Nguyen University of Technology Sydney
Philip Seeman
Philip Seeman University of Toronto
Kevin R. Lynch
Kevin R. Lynch University of Virginia
Henry H.Q. Heng
Henry H.Q. Heng Wayne State University
Bertha K. Madras
Bertha K. Madras Harvard University
Paul J. Fletcher
Paul J. Fletcher Centre for Addiction and Mental Health
Michel Bouvier
Michel Bouvier University of Montreal
Rafael Franco
Rafael Franco University of Barcelona
Lehana Thabane
Lehana Thabane McMaster University

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