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Molecular Biology

D-Index
84
Citations
32245
World Ranking
864
National Ranking
455

Overview

Craig T. Jordan is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily focuses on Medicine, with significant contributions to Biochemistry, Genetics and Molecular Biology. Within these areas, their work extensively covers subfields such as Hematology, Molecular Biology, Immunology, Genetics, and Oncology.

The central themes of their research are centered on Acute Myeloid Leukemia (AML) and related hematologic malignancies. Key topics explored include:

  • Acute Myeloid Leukemia Research
  • Histone Deacetylase Inhibitors Research
  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Chronic Myeloid Leukemia Treatments
  • Acute Lymphoblastic Leukemia Research
  • Hematopoietic Stem Cell Transplantation

Several recent publications highlight their research contributions:

  • "Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia," 2020, Cancer Discovery
  • "Integrative analysis of drug response and clinical outcome in acute myeloid leukemia," 2022, Cancer Cell
  • "Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells," 2020, Nature Cancer
  • "Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells," 2020, Cell Stem Cell
  • "Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia," 2021, Blood Advances

Craig T. Jordan frequently collaborates with a group of co-authors including Brett M. Stevens, Daniel A. Pollyea, Clayton A. Smith, Maria L. Amaya, and Jonathan A. Gutman. The number of joint publications with these colleagues ranges from 25 to over 50, indicating an ongoing collaborative research network.

Their research has been published in several recurring venues, reflecting a consistent focus on hematology and cancer biology. These venues include:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Discovery
  • Haematologica
  • Cancer Research

This body of work reflects a commitment to exploring molecular and clinical aspects of blood cancers, with a particular emphasis on drug resistance mechanisms and therapeutic outcomes in acute myeloid leukemia.

Best Publications

  • Cancer Stem Cells

    Craig T. Jordan;Monica L. Guzman;Mark Noble

  • BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.

    Eleni D. Lagadinou;Alexander Sach;Kevin Callahan;Randall M. Rossi

  • Functional genomic landscape of acute myeloid leukaemia

    Jeffrey W. Tyner;Cristina E. Tognon;Cristina E. Tognon;Daniel Bottomly;Beth Wilmot

  • The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

    CT Jordan;D Upchurch;SJ Szilvassy;ML Guzman

  • Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells

    Monica L. Guzman;Sarah J. Neering;Sarah J. Neering;Sarah J. Neering;Donna Upchurch;Donna Upchurch;Donna Upchurch;Barry Grimes;Barry Grimes;Barry Grimes

  • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

    Monica L. Guzman;Randall M. Rossi;Randall M. Rossi;Lilliana Karnischky;Lilliana Karnischky;Xiaojie Li;Xiaojie Li

  • The Increasing Complexity of the Cancer Stem Cell Paradigm

    Jeffrey M. Rosen;Craig T. Jordan

  • A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

    William Matthews;Craig T. Jordan;Gordon W. Wiegand;Drew Pardoll

  • Clonal and systemic analysis of long-term hematopoiesis in the mouse

    Craig T. Jordan;Ihor R. Lemischka

  • A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

    William Matthews;Craig T. Jordan;Marc Gavin;Nancy A. Jenkins

  • Preferential induction of apoptosis for primary human leukemic stem cells

    Monica L. Guzman;Carol F. Swiderski;Dianna S. Howard;Barry A. Grimes

  • Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.

    Daniel A. Pollyea;Brett M. Stevens;Courtney L. Jones;Amanda Winters

  • Stable transduction of quiescent CD34+CD38− human hematopoietic cells by HIV-1-based lentiviral vectors

    Scott S. Case;Mary A. Price;Craig T. Jordan;Xiao Jin Yu

  • Acute myeloid leukaemia.

    Asim Khwaja;Magnus Bjorkholm;Rosemary E Gale;Ross L Levine

  • An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

    Monica L. Guzman;Randall M. Rossi;Sundar Neelakantan;Xiaojie Li

  • PSORS2 Is Due to Mutations in CARD14

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Katherine C. Pierson

  • Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.

    Unknown

  • Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.

    Courtney L. Jones;Brett M. Stevens;Angelo D'Alessandro;Julie A. Reisz

  • Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting

    Marina Y. Konopleva;Craig T. Jordan

  • The Molecular Basis of Leukemia

    D. Gary Gilliland;Craig T. Jordan;Carolyn A. Felix

Frequent Co-Authors

Peter A. Crooks
Peter A. Crooks University of Arkansas for Medical Sciences
Jane L. Liesveld
Jane L. Liesveld University of Rochester Medical Center
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver
James DeGregori
James DeGregori University of Colorado Anschutz Medical Campus
Travis Nemkov
Travis Nemkov University of Colorado Denver
Ihor R. Lemischka
Ihor R. Lemischka Icahn School of Medicine at Mount Sinai
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Scott A. Armstrong
Scott A. Armstrong Harvard University
Paul S. Brookes
Paul S. Brookes University of Rochester Medical Center
Anne M. Bowcock
Anne M. Bowcock Icahn School of Medicine at Mount Sinai

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