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Medicine

D-Index
89
Citations
28982
World Ranking
12690
National Ranking
6487

Research.com Recognitions

  • 2020 - Member of the National Academy of Medicine (NAM)

Overview

Cynthia E. Dunbar is affiliated with the National Institutes of Health in the United States and has made significant contributions primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans a range of topics with a notable focus on molecular biology, genetics, immunology, and hematology.

Their research covers key areas including virus-based gene therapy research, CRISPR and genetic engineering, hematopoietic stem cell transplantation, acute myeloid leukemia research, CAR-T cell therapy research, immune cell function and interaction, and cancer genomics and diagnostics.

Recent publications exemplify the scope of their work, featuring a variety of studies in prominent scientific venues:

  • Applying a clinical lens to animal models of CAR-T cell therapies, 2022, Molecular Therapy - Methods & Clinical Development
  • In Vivo Tracking of Adoptively Transferred Natural Killer Cells in Rhesus Macaques Using 89Zirconium-Oxine Cell Labeling and PET Imaging, 2020, Clinical Cancer Research
  • Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome, 2020, Haematologica
  • Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias, 2020, Blood Advances
  • Predictors of clonal evolution and myeloid neoplasia following immunosuppressive therapy in severe aplastic anemia, 2022, Leukemia

The frequent co-authors collaborating with Cynthia E. Dunbar include:

  • So Gun Hong
  • Chuanfeng Wu
  • Tae-Hoon Shin
  • David J. Young
  • Xing Fan

Primary publication venues for their work include:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Therapy - Methods & Clinical Development
  • Blood Advances
  • Cell Stem Cell

Their research is concentrated in several subfields, particularly:

  • Molecular Biology
  • Genetics
  • Immunology
  • Hematology
  • Oncology

Recognition within the scientific community includes being named a Member of the National Academy of Medicine in 2020.

Best Publications

  • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

    Marion G Ott;Manfred Schmidt;Kerstin Schwarzwaelder;Stefan Stein

  • Gene therapy comes of age.

    Cynthia E. Dunbar;Katherine A. High;J. Keith Joung;Donald B. Kohn

  • Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation.

    Childs R;Chernoff A;Contentin N;Bahceci E

  • Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

    R E Donahue;S W Kessler;D Bodine;K McDonagh

  • MRI detection of single particles for cellular imaging

    Erik M. Shapiro;Stanko Skrtic;Kathryn Sharer;Jonathan M. Hill

  • Serial Cardiac Magnetic Resonance Imaging of Injected Mesenchymal Stem Cells

    Jonathan M. Hill;Alexander J. Dick;Venkatesh K. Raman;Richard B. Thompson

  • Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation.

    CE Dunbar;M Cottler-Fox;JA O'Shaughnessy;S Doren

  • Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia

    Matthew J. Olnes;Phillip Scheinberg;Katherine R. Calvo;Ronan Desmond

  • Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.

    Danielle M. Townsley;Phillip Scheinberg;Thomas Winkler;Ronan Desmond

  • Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.

    R. V. B. Emmons;D. M. Reid;R. L. Cohen;G. Meng

  • Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells.

    Kathleen A. Hinds;Jonathan M. Hill;Erik M. Shapiro;Mikko O. Laukkanen

  • Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia

    Miriam Y. Kim;Kyung Rok Yu;Saad S. Kenderian;Marco Ruella

  • Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

    S J Brandt;D M Bodine;C E Dunbar;A W Nienhuis

  • Genotoxicity of Retroviral Integration In Hematopoietic Cells

    Arthur W. Nienhuis;Cynthia E. Dunbar;Brian P. Sorrentino

  • Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

    Ronan Desmond;Danielle M. Townsley;Bogdan Dumitriu;Matthew J. Olnes

  • Hepatitis-Associated Aplastic Anemia

    K E Brown;J Tisdale;A J Barrett;C E Dunbar

  • Ex Vivo Expansion of Genetically Marked Rhesus Peripheral Blood Progenitor Cells Results in Diminished Long-Term Repopulating Ability

    J.F. Tisdale;Y. Hanazono;S.E. Sellers;B.A. Agricola

  • Imatinib inhibits T-cell receptor mediated T-cell proliferation and activation in a dose-dependent manner

    Ruth Seggewiss;Karin Loré;Elisabeth Greiner;Magnus K. Magnusson

  • Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

    Peiman Hematti;Bum Kee Hong;Cole Ferguson;Rima Adler

  • CD34+ cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies

    Dimitrios Mavroudis;Elizabeth Read;Michele Cottler-Fox;Daniel Couriel

Frequent Co-Authors

Robert E. Donahue
Robert E. Donahue National Institutes of Health
Neal S. Young
Neal S. Young National Institutes of Health
John F. Tisdale
John F. Tisdale National Institutes of Health
Richard Childs
Richard Childs National Institutes of Health
Susan F. Leitman
Susan F. Leitman National Institutes of Health
Arthur W. Nienhuis
Arthur W. Nienhuis St. Jude Children's Research Hospital
David M. Bodine
David M. Bodine National Institutes of Health
Harry L. Malech
Harry L. Malech National Institutes of Health
Brian P. Sorrentino
Brian P. Sorrentino St. Jude Children's Research Hospital
A. John Barrett
A. John Barrett National Institutes of Health

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