D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 75 Citations 35,349 195 World Ranking 719 National Ranking 48

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Genetic enhancement, Immunology, Genetics, Stem cell and Haematopoiesis. His Genetic enhancement study combines topics from a wide range of disciplines, such as Hematopoietic stem cell transplantation, Transplantation, Transgene, Hematopoietic stem cell and Severe combined immunodeficiency. His research investigates the link between Hematopoietic stem cell and topics such as Cancer research that cross with problems in GLI2.

His study in the field of Immunodeficiency, Bone marrow, Myeloid and Tumor necrosis factor alpha also crosses realms of Respiratory epithelium. His Stem cell research is multidisciplinary, incorporating elements of Chronic granulomatous disease and Virology. His study in Haematopoiesis is interdisciplinary in nature, drawing from both Wiskott–Aldrich syndrome, Primary immunodeficiency and Cell therapy.

His most cited work include:

  • International network of cancer genome projects (1611 citations)
  • A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency (1589 citations)
  • Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy (1141 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Genetic enhancement, Immunology, Genetics, Gene and Haematopoiesis. He interconnects Cancer research, Transgene, Molecular biology, Viral vector and Transplantation in the investigation of issues within Genetic enhancement. His studies deal with areas such as Insertional mutagenesis, Ex vivo, Long terminal repeat and Virology as well as Viral vector.

His Immunology research incorporates elements of Cytotoxic T cell, Hematopoietic stem cell transplantation and Severe combined immunodeficiency. Christof von Kalle focuses mostly in the field of Gene, narrowing it down to topics relating to Cell biology and, in certain cases, CRISPR, Transcription activator-like effector nuclease and Genome editing. His research in Haematopoiesis intersects with topics in Progenitor cell, Myeloid and Bone marrow.

He most often published in these fields:

  • Genetic enhancement (30.05%)
  • Immunology (25.35%)
  • Genetics (17.37%)

What were the highlights of his more recent work (between 2018-2021)?

  • Artificial intelligence (7.04%)
  • Melanoma (6.10%)
  • Deep learning (4.23%)

In recent papers he was focusing on the following fields of study:

Christof von Kalle mostly deals with Artificial intelligence, Melanoma, Deep learning, Convolutional neural network and Severe acute respiratory syndrome coronavirus 2. He has researched Artificial intelligence in several fields, including Receiver operating characteristic, Medical diagnosis and Skin cancer. His Melanoma research includes elements of Dermatology, Prospective data, Early detection and Deep neural networks.

The Prospective data study which covers Oncology that intersects with Cancer. His study looks at the relationship between Deep learning and topics such as Artificial neural network, which overlap with Robustness, Learnability, Digital pathology and Data set. Christof von Kalle incorporates Trajectory analysis and Cancer research in his research.

Between 2018 and 2021, his most popular works were:

  • Pan-cancer analysis of whole genomes (538 citations)
  • COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. (243 citations)
  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. (226 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His scientific interests lie mostly in Artificial intelligence, Deep learning, University hospital, Contextual image classification and Convolutional neural network. Christof von Kalle works mostly in the field of Artificial intelligence, limiting it down to topics relating to Receiver operating characteristic and, in certain cases, Pattern recognition and Resident physician, as a part of the same area of interest. His study ties his expertise on Medical diagnosis together with the subject of Deep learning.

Christof von Kalle works mostly in the field of Medical diagnosis, limiting it down to topics relating to Histopathology and, in certain cases, Breast cancer, Melanoma diagnosis, Benign nevus and Radiology. His Contextual image classification research is multidisciplinary, incorporating perspectives in Dermatology and Confidence interval. His research integrates issues of Algorithm and Benchmark in his study of Melanoma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency

Salima Hacein-Bey-Abina;Christof Von Kalle;Manfred Schmidt;Françoise Le Deist.
The New England Journal of Medicine (2003)

2312 Citations

International network of cancer genome projects

Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker.
(2010)

1839 Citations

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

Nathalie Cartier;Salima Hacein-Bey-Abina;Cynthia C. Bartholomae;Gabor Veres.
Science (2009)

1606 Citations

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Marion G Ott;Manfred Schmidt;Kerstin Schwarzwaelder;Stefan Stein.
Nature Medicine (2006)

1309 Citations

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

Steven J. Howe;Marc R. Mansour;Kerstin Schwarzwaelder;Cynthia Bartholomae.
Journal of Clinical Investigation (2008)

1295 Citations

Pan-cancer analysis of whole genomes

Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart.
(2020)

1275 Citations

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani.
Science (2013)

1201 Citations

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua.
Science (2013)

1088 Citations

Dissecting the genomic complexity underlying medulloblastoma

David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner.
Nature (2012)

850 Citations

COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.

Robert Lorenz Chua;Soeren Lukassen;Saskia Trump;Bianca P. Hennig.
Nature Biotechnology (2020)

844 Citations

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