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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
17945
World Ranking
1120
National Ranking
87

Medicine

D-Index
77
Citations
17986
World Ranking
18557
National Ranking
978

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award

Overview

Christopher Baum is affiliated with Charité - University Medicine Berlin in Germany. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with specific attention to Genetics, Molecular Biology, Oncology, Clinical Psychology, and Emergency Medical Services.

The scientist's work addresses multiple topics including:

  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • CAR-T cell therapy research
  • Resilience and Mental Health
  • Disaster Response and Management
  • Climate Change and Health Impacts

Among recent published papers, two notable studies are:

  • Multiple Genes Surrounding Bcl-xL, a Common Retroviral Insertion Site, Can Influence Hematopoiesis Individually or in Concert, published in 2020 in Human Gene Therapy
  • Population-level effects of Hurricane Sandy on adolescent health, published in 2024 in Journal of Affective Disorders

Frequent collaborators include Teng-Cheong Ha, Maike Stahlhut, Michael Rothe, Gabi Paul, and Violetta Dziadek, each contributing to at least one joint publication.

Christopher Baum's research outputs have appeared predominantly in the journals Human Gene Therapy and Journal of Affective Disorders, demonstrating a cross-disciplinary approach spanning molecular biology and clinical psychology.

Best Publications

  • Murine leukemia induced by retroviral gene marking.

    Zhixiong Li;Zhixiong Li;Jochen Düllmann;Bernd Schiedlmeier;Manfred Schmidt

  • Side effects of retroviral gene transfer into hematopoietic stem cells

    Christopher Baum;Jochen Düllmann;Zhixiong Li;Boris Fehse

  • Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

    Ute Modlich;Susana Navarro;Daniela Zychlinski;Tobias Maetzig

  • A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Sung Yun Pai;H. Bobby Gaspar;Myriam Armant

  • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

    Christopher Baum;Olga Kustikova;Ute Modlich;Zhixiong Li

  • Clonal Dominance of Hematopoietic Stem Cells Triggered by Retroviral Gene Marking

    Olga Kustikova;Boris Fehse;Ute Modlich;Min Yang

  • Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

    Ute Modlich;Jens Bohne;Manfred Schmidt;Christof von Kalle

  • Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors

    Daniela Zychlinski;Axel Schambach;Ute Modlich;Tobias Maetzig

  • Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells.

    C Baum;S Hegewisch-Becker;H G Eckert;C Stocking

  • Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

    Eva Warlich;Johannes Kuehle;Tobias Cantz;Tobias Cantz;Martijn H Brugman

  • Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

    Christopher Baum;Christof von Kalle;Frank J.T Staal;Zhixiong Li

  • Retroviral Vectors for High-Level Transgene Expression in T Lymphocytes

    Boris Engels;Hakan Cam;Thomas Schüler;Stefano Indraccolo

  • Gammaretroviral vectors: biology, technology and application.

    Tobias Maetzig;Melanie Galla;Christopher Baum;Axel Schambach

  • Resistance of mature T cells to oncogene transformation.

    Sebastian Newrzela;Kerstin Cornils;Zhixiong Li;Christopher Baum

  • Context Dependence of Different Modules for Posttranscriptional Enhancement of Gene Expression from Retroviral Vectors

    Axel Schambach;Harald Wodrich;Markus Hildinger;Jens Bohne

  • Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

    Markus Hildinger;Kristin L. Abel;Wolfram Ostertag;Christopher Baum

  • High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation.

    Bernhard Schiedlmeier;Hannes Klump;Elke Will;Goekhan Arman-Kalcek

  • LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

    Julia Skokowa;Gunnar Cario;Murat Uenalan;Axel Schambach

  • Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine–DNA methyltransferase in hematopoietic cells

    Axel Schambach;Jens Bohne;Saurabh Chandra;Elke Will

  • Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis

    Ute Modlich;Olga S Kustikova;Manfred Schmidt;Cornelia Rudolph

Frequent Co-Authors

Axel Schambach
Axel Schambach Hannover Medical School
Boris Fehse
Boris Fehse Universität Hamburg
Wolfram Ostertag
Wolfram Ostertag Universität Hamburg
David A. Williams
David A. Williams Boston Children's Hospital
Adrian J. Thrasher
Adrian J. Thrasher University College London
Brigitte Schlegelberger
Brigitte Schlegelberger Hannover Medical School
Dorothee von Laer
Dorothee von Laer Innsbruck Medical University
Christof von Kalle
Christof von Kalle Charité - University Medicine Berlin
Geoffrey P. Margison
Geoffrey P. Margison University of Manchester
Punam Malik
Punam Malik Cincinnati Children's Hospital Medical Center

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