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Biology and Biochemistry

D-Index
47
Citations
7878
World Ranking
18719
National Ranking
7651

Overview

Punam Malik is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with contributions focused on Genetics, Molecular Biology, Hematology, Physiology, and Oncology as subfields.

The scientist's work covers several main topics, including:

  • Hemoglobinopathies and Related Disorders
  • CRISPR and Genetic Engineering
  • Virus-based Gene Therapy Research
  • Iron Metabolism and Disorders
  • RNA Interference and Gene Delivery
  • Biomedical Ethics and Regulation
  • Erythrocyte Function and Pathophysiology

Recent notable publications by Punam Malik include:

  • "Progression of albuminuria in patients with sickle cell anemia: a multicenter, longitudinal study," 2020, Blood Advances
  • "Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)," 2021, Gene Therapy
  • "Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics-guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia," 2021, British Journal of Haematology
  • "Strategies for precise gene edits in mammalian cells," 2023, Molecular Therapy - Nucleic Acids
  • "FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice," 2021, Blood Advances

The scientist frequently publishes in the following venues:

  • Blood
  • Blood Advances
  • Human Gene Therapy
  • Gene Therapy
  • Scientific Reports

Punam Malik has collaborated often with several researchers, including:

  • Omar Niss
  • Charles T. Quinn
  • Mengna Chi
  • Theodosia A. Kalfa
  • Sydney Felker

Best Publications

  • A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Sung Yun Pai;H. Bobby Gaspar;Myriam Armant

  • Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor

    Suresh K. Selvaraj;Ranjit K. Giri;Natalya Perelman;Cage Johnson

  • Pulmonary macrophage transplantation therapy

    Takuji Suzuki;Paritha Arumugam;Takuro Sakagami;Nico Lachmann

  • Successful correction of the human β-thalassemia major phenotype using a lentiviral vector

    Geetha Puthenveetil;Jessica Scholes;Jessica Scholes;Denysha Carbonell;Denysha Carbonell;Naveen Qureshi;Naveen Qureshi

  • Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management

    Samir K. Ballas;Muge R. Kesen;Morton F. Goldberg;Gerard A. Lutty

  • Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease.

    Alex George;Suvarnamala Pushkaran;Diamantis G. Konstantinidis;Sebastian Koochaki

  • Placenta growth factor activates monocytes and correlates with sickle cell disease severity

    Natalya Perelman;Suresh K. Selvaraj;Sandeep Batra;Lori R. Luck

  • Pediatric Tumor Cells Express Erythropoietin and a Functional Erythropoietin Receptor that Promotes Angiogenesis and Tumor Cell Survival

    Sandeep Batra;Natalya Perelman;Natalya Perelman;Lori R Luck;Lori R Luck;Hiroyuki Shimada;Hiroyuki Shimada

  • Ineffective erythropoiesis in β-thalassemia major is due to apoptosis at the polychromatophilic normoblast stage

    Liesl A Mathias;Timothy C Fisher;Licheng Zeng;Herbert J Meiselman

  • Therapeutic strategies for sickle cell disease: towards a multi-agent approach.

    Marilyn J. Telen;Punam Malik;Gregory M. Vercellotti

  • CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites

    Rajeswari Jayavaradhan;Devin M. Pillis;Michael Goodman;Fan Zhang

  • G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment

    Xiaoji Chen;Kyobi Skutt-Kakaria;Kyobi Skutt-Kakaria;Jerry Davison;Yang Li Ou

  • Improved Human β-globin Expression from Self-inactivating Lentiviral Vectors Carrying the Chicken Hypersensitive Site-4 (cHS4) Insulator Element

    Paritha I Arumugam;Jessica Scholes;Natalya Perelman;Ping Xia

  • High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors.

    Francois Moreau-Gaudry;Ping Xia;Ping Xia;Gang Jiang;Gang Jiang;Natalya P. Perelman

  • Constitutive HOXA5 Expression Inhibits Erythropoiesis and Increases Myelopoiesis From Human Hematopoietic Progenitors

    John Fuller;John Fuller;Denise Petersen;Denise Petersen;Parvin Izadi;Parvin Izadi

  • Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease

    Omar Niss;Charles T. Quinn;Adam Lane;Joshua Daily

  • Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

    Nathan Salomonis;Phillip J. Dexheimer;Larsson Omberg;Robin Schroll

  • An In Vitro Model of Human Red Blood Cell Production From Hematopoietic Progenitor Cells

    Punam Malik;Timothy C. Fisher;Lora L.W. Barsky;Licheng Zeng

  • Pathophysiology and therapy for haemoglobinopathies. Part I: sickle cell disease.

    Catherine Madigan;Punam Malik

  • Efficacy of gene therapy for X-linked severe combined immunodeficiency: update on trial No.1 follow-up and preliminary results of multicentric collaborative trial No. 2 (Paris - Boston - London)

    S Hacein-Bey-Abina;L Caccaveli;F Touzot;L Dal-Cortivo

Frequent Co-Authors

Donald B. Kohn
Donald B. Kohn University of California, Los Angeles
Russell E. Ware
Russell E. Ware Cincinnati Children's Hospital Medical Center
Adrian J. Thrasher
Adrian J. Thrasher University College London
Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center
Hans Peter Kiem
Hans Peter Kiem Fred Hutchinson Cancer Research Center
Axel Schambach
Axel Schambach Hannover Medical School
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center
David A. Williams
David A. Williams Boston Children's Hospital
Michael B. Jordan
Michael B. Jordan Cincinnati Children's Hospital Medical Center
Christopher Baum
Christopher Baum Charité - University Medicine Berlin

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