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Genetics

D-Index
112
Citations
43898
World Ranking
499
National Ranking
256

Medicine

D-Index
113
Citations
46252
World Ranking
4963
National Ranking
2694

Overview

Bruce J. Aronow is affiliated with Cincinnati Children's Hospital Medical Center in the United States. The research contributions focus primarily on biochemistry, genetics, and molecular biology, with significant work also in medicine. The subfields of study encompass molecular biology, genetics, infectious diseases, immunology, and artificial intelligence.

The scope of research topics includes:

  • Single-cell and spatial transcriptomics
  • COVID-19 clinical research studies
  • Cell image analysis techniques
  • Cerebral palsy and movement disorders
  • Congenital heart defects research
  • Long-term effects of COVID-19
  • Epigenetics and DNA methylation

Frequent co-authors in the scientific collaborations are:

  • Kang Jin
  • Gabriel A. Brat
  • Tianxi Cai
  • Alba Gutiérrez-Sacristán
  • David A. Hanauer

Publications have been regularly featured in several venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • UNC Libraries
  • eLife
  • EClinicalMedicine

Representative recent papers include the following titles along with their year of publication and venue:

  • A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm, 2020, eLife
  • A roadmap for the Human Developmental Cell Atlas, 2021, Nature
  • Evolving phenotypes of non-hospitalized patients that indicate long COVID, 2021, BMC Medicine
  • A census of the lung: CellCards from LungMAP, 2021, Developmental Cell
  • Guided construction of single cell reference for human and mouse lung, 2023, Nature Communications

Best Publications

  • ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

    Jing Chen;Eric E. Bardes;Bruce J. Aronow;Anil G. Jegga

  • Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis

    Carine Blanchard;Ning Wang;Keith F. Stringer;Anil Mishra

  • Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

    Elizabeth B. Wilson;Douglas H. Yamada;Heidi Elsaesser;Jonathan Herskovitz

  • Genetic lineage tracing defines myofibroblast origin and function in the injured heart

    Onur Kanisicak;Hadi Khalil;Malina J. Ivey;Jason Karch

  • The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

    Anne E. Powell;Yang Wang;Yina Li;Emily J. Poulin

  • Canonical Genetic Signatures of the Adult Human Brain

    Michael Hawrylycz;Jeremy A. Miller;Vilas Menon;David Feng

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

    Karen I Zeller;Anil G Jegga;Bruce J Aronow;Kathryn A O'Donnell

  • Design and implementation of microarray gene expression markup language (MAGE-ML)

    Paul T Spellman;Michael Miller;Jason Stewart;Charles Troup

  • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

    Yael Haberman;Timothy L. Tickle;Phillip J. Dexheimer;Mi-Ok Kim

  • Single-cell analysis of mixed-lineage states leading to a binary cell fate choice

    Andre Olsson;Meenakshi Venkatasubramanian;Viren K. Chaudhri;Bruce J. Aronow

  • Genetic Manipulation of Periostin Expression Reveals a Role in Cardiac Hypertrophy and Ventricular Remodeling

    Toru Oka;Jian Xu;Jian Xu;Robert A. Kaiser;Robert A. Kaiser;Jaime Melendez;Jaime Melendez

  • ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition: Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo

    Ronald B DeMattos;John R Cirrito;Maia Parsadanian;Patrick C May

  • Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

    Toru Oka;Marjorie Maillet;Alistair J. Watt;Robert J. Schwartz

  • TRIM24 links a non-canonical histone signature to breast cancer

    Wen Wei Tsai;Zhanxin Wang;Teresa T. Yiu;Teresa T. Yiu;Kadir C. Akdemir

  • Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers

    Giuseppina Bonizzi;Magali Bebien;Dennis C Otero;Kirsten E Johnson-Vroom

  • Disease candidate gene identification and prioritization using protein interaction networks

    Jing Chen;Jing Chen;Bruce J Aronow;Bruce J Aronow;Bruce J Aronow;Anil G Jegga;Anil G Jegga

  • MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity.

    Thomas X. Lu;Jochen Hartner;Jochen Hartner;Eun-Jin Lim;Victoria Fabry

  • Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays.

    Jung Whan Kim;Karen I. Zeller;Yunyue Wang;Anil G. Jegga;Anil G. Jegga

  • Genetic Manipulation of Periostin Expression Reveals a Role in Cardiac Hypertrophy and Ventricular Remodeling

    Toru Oka;Robert A. Kaiser;Jaime Melendez;Jeffery D. Molkentin

Frequent Co-Authors

Anil G. Jegga
Anil G. Jegga Cincinnati Children's Hospital Medical Center
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
Subra Kugathasan
Subra Kugathasan Emory University
Jeffrey S. Hyams
Jeffrey S. Hyams University of Connecticut
David P. Witte
David P. Witte Cincinnati Children's Hospital Medical Center
Anne M. Griffiths
Anne M. Griffiths University of Toronto
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Jeffery D. Molkentin
Jeffery D. Molkentin Cincinnati Children's Hospital Medical Center
S. Steven Potter
S. Steven Potter Cincinnati Children's Hospital Medical Center

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