Frank R. Sharp spends much of his time researching Ischemia, Internal medicine, Neuroscience, Endocrinology and Heat shock protein. His Ischemia study incorporates themes from Hypoxia, Gene expression, Stroke, Cerebral infarction and Pathology. His studies examine the connections between Internal medicine and genetics, as well as such issues in Neurogenesis, with regards to NeuN.
The concepts of his Neuroscience study are interwoven with issues in Dizocilpine and Phencyclidine. His Endocrinology research includes elements of NMDA receptor and Cell biology. His Heat shock protein research is multidisciplinary, incorporating perspectives in Immunocytochemistry, Status epilepticus, Signal transduction and Penumbra.
His main research concerns Internal medicine, Endocrinology, Neuroscience, Ischemia and Pathology. His Internal medicine study combines topics from a wide range of disciplines, such as Neocortex and Cardiology. Frank R. Sharp has researched Endocrinology in several fields, including NMDA receptor and c-Fos.
His biological study spans a wide range of topics, including Heat shock protein and Hypoxia. Frank R. Sharp combines subjects such as Immunocytochemistry and Cell biology with his study of Heat shock protein. His Pathology research incorporates themes from Magnetic resonance imaging, Cerebral infarction, Heme oxygenase and Infarction.
Frank R. Sharp mostly deals with Stroke, Internal medicine, Gene expression, microRNA and Ischemic stroke. His work carried out in the field of Stroke brings together such families of science as Transcriptome, Pathogenesis, Blood–brain barrier and Bioinformatics. His research integrates issues of Endocrinology, Oncology and Cardiology in his study of Internal medicine.
His research in Gene expression intersects with topics in Immune system and Pathology. While the research belongs to areas of microRNA, Frank R. Sharp spends his time largely on the problem of Autism, intersecting his research to questions surrounding Neuroscience, Human genetics, Temporal cortex and Small nucleolar RNA. Frank R. Sharp studies Hippocampus, a branch of Neuroscience.
Frank R. Sharp mainly focuses on Stroke, Bioinformatics, Immunology, Brain ischemia and Pathology. His studies deal with areas such as Biomarker, Intracerebral hemorrhage, Gene expression and Angiogenesis as well as Bioinformatics. His research ties Ischemia and Immunology together.
His work deals with themes such as Transforming growth factor beta and Neuroinflammation, which intersect with Ischemia. His study in Brain ischemia is interdisciplinary in nature, drawing from both Heat shock protein, Biochemistry, Shock, Ischemic stroke and Heme. His study with Blood–brain barrier involves better knowledge in Internal medicine.
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Expression of c-fos protein in brain: metabolic mapping at the cellular level
S. M. Sagar;Frank R Sharp;T. Curran.
Science (1988)
A Semiautomated Method for Measuring Brain Infarct Volume
Raymond A. Swanson;Raymond A. Swanson;Matthew T. Morton;George Tsao-Wu;George Tsao-Wu;Robert A. Savalos;Robert A. Savalos.
Journal of Cerebral Blood Flow and Metabolism (1990)
Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils.
Jialing Liu;Karen Solway;Robert O. Messing;Frank R. Sharp.
The Journal of Neuroscience (1998)
Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain
Marcelle Bergeron;Jeffrey M. Gidday;Aimee Y. Yu;Gregg L. Semenza.
Annals of Neurology (2000)
Multiple molecular penumbras after focal cerebral ischemia.
Frank R. Sharp;Aigang Lu;Yang Tang;David E. Millhorn.
Journal of Cerebral Blood Flow and Metabolism (2000)
c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress
Frank R Sharp;S. M. Sagar;K. Hicks;D. Lowenstein.
The Journal of Neuroscience (1991)
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis
Guodong Cao;Wei Pei;Hailiang Ge;Qinhua Liang.
The Journal of Neuroscience (2002)
HIF1 and oxygen sensing in the brain
Frank R. Sharp;Frank R. Sharp;Myriam Bernaudin.
Nature Reviews Neuroscience (2004)
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain.
Marcelle Bergeron;Aimee Y. Yu;Karen E. Solway;Gregg L. Semenza.
European Journal of Neuroscience (1999)
Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures.
Da Zhi Liu;Yingfang Tian;Bradley P. Ander;Huichun Xu.
Journal of Cerebral Blood Flow and Metabolism (2010)
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