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Medicine

D-Index
112
Citations
44118
World Ranking
5155
National Ranking
2788

Overview

Frank R. Sharp is affiliated with the University of California, Davis in the United States. Their research spans a broad range of topics primarily within medicine, biochemistry, genetics, molecular biology, and neuroscience. Their work emphasizes neurology, molecular biology, epidemiology, immunology, and cancer research.

Their main research topics include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Acute Ischemic Stroke Management
  • S100 Proteins and Annexins
  • Immune cells in cancer
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer-related molecular mechanisms research

Sharp has published extensively, with frequent appearances in publication venues such as:

  • Stroke
  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroinflammation
  • Brain

Selected recent papers include:

  • Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke, 2020, Journal of Cerebral Blood Flow & Metabolism
  • Molecular Correlates of Hemorrhage and Edema Volumes Following Human Intracerebral Hemorrhage Implicate Inflammation, Autophagy, mRNA Splicing, and T Cell Receptor Signaling, 2020, Translational Stroke Research
  • Early peripheral blood gene expression associated with good and poor 90-day ischemic stroke outcomes, 2023, Journal of Neuroinflammation
  • Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke, 2022, Brain
  • Bacterial lipopolysaccharide is associated with stroke, 2021, Scientific Reports

Frequent collaborators in Sharp's research include:

  • Bradley P. Ander
  • Glen C. Jickling
  • Heather Hull
  • Boryana Stamova
  • Hajar Amini

Best Publications

  • Expression of c-fos protein in brain: metabolic mapping at the cellular level

    S. M. Sagar;Frank R Sharp;T. Curran

  • A Semiautomated Method for Measuring Brain Infarct Volume

    Raymond A. Swanson;Raymond A. Swanson;Matthew T. Morton;George Tsao-Wu;George Tsao-Wu;Robert A. Savalos;Robert A. Savalos

  • Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils.

    Jialing Liu;Karen Solway;Robert O. Messing;Frank R. Sharp

  • HIF1 and oxygen sensing in the brain

    Frank R. Sharp;Frank R. Sharp;Myriam Bernaudin

  • Engaging neuroscience to advance translational research in brain barrier biology

    Edward A. Neuwelt;Björn Bauer;Christoph Fahlke;Gert Fricker

  • Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain

    Marcelle Bergeron;Jeffrey M. Gidday;Aimee Y. Yu;Gregg L. Semenza

  • Multiple molecular penumbras after focal cerebral ischemia.

    Frank R. Sharp;Aigang Lu;Yang Tang;David E. Millhorn

  • Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures.

    Da Zhi Liu;Yingfang Tian;Bradley P. Ander;Huichun Xu

  • c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress

    Frank R Sharp;S. M. Sagar;K. Hicks;D. Lowenstein

  • In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

    Guodong Cao;Wei Pei;Hailiang Ge;Qinhua Liang

  • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain.

    Marcelle Bergeron;Aimee Y. Yu;Karen E. Solway;Gregg L. Semenza

  • Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans

    Glen C Jickling;DaZhi Liu;Boryana Stamova;Bradley P Ander

  • Targeting neutrophils in ischemic stroke: translational insights from experimental studies

    Glen C Jickling;DaZhi Liu;Bradley P Ander;Boryana Stamova

  • Heat-shock protein protection

    Frank R Sharp;Stephen M Massa;Raymond A Swanson

  • Heme and iron metabolism: role in cerebral hemorrhage.

    Kenneth R. Wagner;Frank R. Sharp;Timothy D. Ardizzone;Aigang Lu

  • Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.

    Faisal Adhami;Faisal Adhami;Guanghong Liao;Yury M. Morozov;Aryn Schloemer

  • Gram-negative bacterial molecules associate with Alzheimer disease pathology

    Xinhua Zhan;Boryana Stamova;Lee Way Jin;Charles Decarli

  • Brain Genomic Response following Hypoxia and Re-oxygenation in the Neonatal Rat IDENTIFICATION OF GENES THAT MIGHT CONTRIBUTE TO HYPOXIA-INDUCED ISCHEMIC TOLERANCE

    Myriam Bernaudin;Yang Tang;Melinda Reilly;Edwige Petit

  • Heat shock proteins as markers of neural injury.

    Manuel F. Gonzalez;Kazuya Shiraishi;Kinya Hisanaga;Stephen M. Sagar

  • Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke.

    Renée J. Turner;Frank R. Sharp

Frequent Co-Authors

Stephen M. Sagar
Stephen M. Sagar University of California, San Francisco
Raymond A. Swanson
Raymond A. Swanson University of California, San Francisco
Philip Weinstein
Philip Weinstein University of Adelaide
Joseph P. Broderick
Joseph P. Broderick University of Cincinnati
Pak H. Chan
Pak H. Chan Stanford University
Jari Koistinaho
Jari Koistinaho University of Helsinki
Tracy A. Glauser
Tracy A. Glauser Cincinnati Children's Hospital Medical Center
Linda Noble
Linda Noble University of California, San Francisco
Jialing Liu
Jialing Liu University of California, San Francisco
Steven H. Graham
Steven H. Graham University of Pittsburgh

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