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Medicine

D-Index
107
Citations
39409
World Ranking
6295
National Ranking
3357

Overview

Richard F. Keep is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple disciplines within the medical and neuroscience fields, with a focus on neurologically related conditions and mechanisms.

Their primary fields of study include Medicine and Neuroscience, while their subfields of specialization cover Neurology, Epidemiology, Cellular and Molecular Neuroscience, Molecular Biology, and Pediatrics, Perinatology and Child Health.

The main topics covered in their work are:

  • Intracerebral and Subarachnoid Hemorrhage Research
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cerebrospinal fluid and hydrocephalus
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurosurgical Procedures and Complications
  • Barrier Structure and Function Studies

Frequent co-authors who have collaborated extensively with Richard F. Keep are:

  • Guohua Xi
  • Ya Hua
  • Fenghui Ye
  • Sravanthi Koduri
  • Aditya S. Pandey

The scientist has published numerous articles in several core venues, notably:

  • Fluids and Barriers of the CNS
  • Translational Stroke Research
  • Stroke
  • Experimental Neurology
  • Neurobiology of Disease

Recent papers authored or co-authored by Richard F. Keep include:

  • "Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited," 2022, published in Fluids and Barriers of the CNS
  • "Brain edema formation and therapy after intracerebral hemorrhage," 2022, published in Neurobiology of Disease
  • "Novel targets, treatments, and advanced models for intracerebral haemorrhage," 2022, published in EBioMedicine
  • "Blood-Brain Barrier Dysfunction in Normal Aging and Neurodegeneration: Mechanisms, Impact, and Treatments," 2023, published in Stroke
  • "The Role of Thrombin in Brain Injury After Hemorrhagic and Ischemic Stroke," 2020, published in Translational Stroke Research

Best Publications

  • Mechanisms of brain injury after intracerebral haemorrhage

    Guohua Xi;Richard F Keep;Julian T Hoff

  • Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

    Richard F Keep;Ya Hua;Guohua Xi

  • Blood-brain barrier dysfunction and recovery after ischemic stroke.

    Xiaoyan Jiang;Xiaoyan Jiang;Anuska V. Andjelkovic;Ling Zhu;Tuo Yang

  • Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products

    Feng Ping Huang;Guohua Xi;Richard F. Keep;Ya Hua

  • Behavioral Tests After Intracerebral Hemorrhage in the Rat

    Ya Hua;Timothy J Schallert;Richard F. Keep;Jimin Wu

  • Brain endothelial cell-cell junctions: how to "open" the blood brain barrier.

    Svetlana M Stamatovic;Richard F Keep;Anuska V Andjelkovic

  • Iron and Iron-Handling Proteins in the Brain After Intracerebral Hemorrhage

    Jimin Wu;Ya Hua;Richard F. Keep;Takehiro Nakamura

  • Potential role of MCP-1 in endothelial cell tight junction `opening': signaling via Rho and Rho kinase

    Svetlana M. Stamatovic;Richard F. Keep;Steven L. Kunkel;Anuska V. Andjelkovic

  • Monocyte Chemoattractant Protein-1 Regulation of Blood–Brain Barrier Permeability:

    Svetlana M Stamatovic;Parvin Shakui;Richard F Keep;Bethany B Moore

  • Edema from intracerebral hemorrhage: the role of thrombin.

    K. R. Lee;G. P. Colon;A. L. Betz;R. F. Keep

  • The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury : deleterious or protective?

    Guohua Xi;Georg Reiser;Richard F. Keep

  • Role of Blood Clot Formation on Early Edema Development After Experimental Intracerebral Hemorrhage

    Guohua Xi;Kenneth R. Wagner;Kenneth R. Wagner;Richard F. Keep;Ya Hua

  • Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats

    Guohua Xi;Richard F. Keep;Julian T. Hoff

  • Acute inflammatory reaction following experimental intracerebral hemorrhage in rat.

    Chao Gong;Julian T Hoff;Richard F Keep

  • Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury.

    Yejie Shi;Yejie Shi;Lili Zhang;Lili Zhang;Lili Zhang;Hongjian Pu;Hongjian Pu;Leilei Mao;Leilei Mao

  • Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage.

    Takehiro Nakamura;Richard F. Keep;Ya Hua;Timothy J Schallert

  • Absence of the Chemokine Receptor CCR2 Protects Against Cerebral Ischemia/Reperfusion Injury in Mice

    Oliver B. Dimitrijevic;Svetlana M. Stamatovic;Richard F. Keep;Anuska V. Andjelkovic

  • Intracerebral hemorrhage-induced neuronal death.

    Chao Gong;Nicholas Boulis;Jun Qian;Danielle E. Turner

  • Brain injury after intracerebral hemorrhage: the role of thrombin and iron.

    Ya Hua;Richard F. Keep;Julian T. Hoff;Guohua Xi

  • Junctional proteins of the blood-brain barrier: New insights into function and dysfunction

    Svetlana M Stamatovic;Allison M Johnson;Richard F Keep;Anuska V Andjelkovic

Frequent Co-Authors

Guohua Xi
Guohua Xi University of Michigan–Ann Arbor
Julian T. Hoff
Julian T. Hoff University of Michigan–Ann Arbor
Timothy J Schallert
Timothy J Schallert The University of Texas at Austin
Yejie Shi
Yejie Shi University of Pittsburgh
Scott D. Larsen
Scott D. Larsen University of Michigan–Ann Arbor
R. Anne Stetler
R. Anne Stetler University of Pittsburgh
Thomas L. Chenevert
Thomas L. Chenevert University of Michigan–Ann Arbor
Joseph P. Broderick
Joseph P. Broderick University of Cincinnati
Lewis B. Morgenstern
Lewis B. Morgenstern University of Michigan–Ann Arbor
Rajiv R. Ratan
Rajiv R. Ratan Cornell University

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