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Neuroscience

D-Index
124
Citations
56379
World Ranking
338
National Ranking
203

Medicine

D-Index
124
Citations
56459
World Ranking
3231
National Ranking
1781

Overview

Eng H. Lo is affiliated with Harvard University in the United States and has contributed extensively to the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their research spans multiple subfields including neurology, molecular biology, epidemiology, physiology, and pulmonary and respiratory medicine.

Their main research topics include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Acute Ischemic Stroke Management
  • Neurological Disease Mechanisms and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Circadian Rhythm and Melatonin
  • Barrier Structure and Function Studies

Eng H. Lo has published frequently in journals such as:

  • Stroke
  • Journal of Cerebral Blood Flow & Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Circulation Research

Notable recent papers by Eng H. Lo include:

  • Potential circadian effects on translational failure for neuroprotection, 2020, Nature
  • The future of neuroprotection in stroke, 2020, Journal of Neurology Neurosurgery & Psychiatry
  • Placental Mitochondria Therapy for Cerebral Ischemia-Reperfusion Injury in Mice, 2020, Stroke
  • Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study, 2022, PLoS Medicine
  • The neurovascular unit and systemic biology in stroke - implications for translation and treatment, 2022, Nature Reviews Neurology

Frequent collaborators include:

  • Ken Arai
  • Wenlu Li
  • MingMing Ning
  • Emiri T. Mandeville
  • Kazuhide Hayakawa

Best Publications

  • Mechanisms, challenges and opportunities in stroke

    Eng H. Lo;Turgay Dalkara;Michael A. Moskowitz

  • The Science of Stroke: Mechanisms in Search of Treatments

    Michael A. Moskowitz;Eng H. Lo;Costantino Iadecola

  • Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

    Marc Fisher;Marc Fisher;Giora Z. Feuerstein;David W. Howells;Patricia D. Hurn

  • Transfer of mitochondria from astrocytes to neurons after stroke

    Kazuhide Hayakawa;Elga Esposito;Xiaohua Wang;Xiaohua Wang;Yasukazu Terasaki

  • Effects of Matrix Metalloproteinase-9 Gene Knock-Out on the Proteolysis of Blood–Brain Barrier and White Matter Components after Cerebral Ischemia

    Minoru Asahi;Xiaoying Wang;Tatsuro Mori;Toshihisa Sumii

  • Role for Matrix Metalloproteinase 9 after Focal Cerebral Ischemia: Effects of Gene Knockout and Enzyme Inhibition with BB-94:

    Minoru Asahi;Kazuko Asahi;Jae-Chang Jung;Gregory J. del Zoppo

  • Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

    Yasuhiko Kawasaki;Zhen Zhong Xu;Xiaoying Wang;Jong Yeon Park

  • Role of matrix metalloproteinases in delayed cortical responses after stroke.

    Bing-Qiao Zhao;Sophia Wang;Hahn-Young Kim;Hahn-Young Kim;Hannah Storrie

  • A new penumbra: transitioning from injury into repair after stroke

    Eng H Lo

  • MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

    Anna Rosell;Eloy Cuadrado;Arantxa Ortega-Aznar;Mar Hernández-Guillamon

  • Cortical spreading depression activates and upregulates MMP-9

    Yasemin Gursoy-Ozdemir;Jianhua Qiu;Norihiro Matsuoka;Hayrunnisa Bolay

  • Involvement of Matrix Metalloproteinase in Thrombolysis-Associated Hemorrhagic Transformation After Embolic Focal Ischemia in Rats

    Toshihisa Sumii;Eng H. Lo

  • Increased Brain Expression of Matrix Metalloproteinase-9 After Ischemic and Hemorrhagic Human Stroke

    Anna Rosell;Arantxa Ortega-Aznar;José Alvarez-Sabín;Israel Fernández-Cadenas

  • Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.

    Xiaoying Wang;Sun-Ryung Lee;Ken Arai;Seong-Ryong Lee

  • Pathophysiologic cascades in ischemic stroke.

    Changhong Xing;Ken Arai;Eng H. Lo;Marc Hommel

  • Stroke: Working toward a prioritized world agenda

    Vladimir Hachinski;Geoffrey A. Donnan;Philip B. Gorelick;Werner Hacke

  • Evidence for Apoptosis After Intracerebral Hemorrhage in Rat Striatum

    Kohji Matsushita;Wei Meng;Xiaoying Wang;Minoru Asahi

  • Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

    Sava Sakadžić;Emmanuel Roussakis;Mohammad A Yaseen;Emiri T Mandeville

  • Junctional complexes of the blood–brain barrier: permeability changes in neuroinflammation

    Margaret A Petty;Eng H Lo

  • Effects of Matrix Metalloproteinase-9 Gene Knock-Out on Morphological and Motor Outcomes after Traumatic Brain Injury

    Xiaoying Wang;JaeChang Jung;Minoru Asahi;Wilson Chwang

Frequent Co-Authors

Michael A. Moskowitz
Michael A. Moskowitz Harvard University
David A. Boas
David A. Boas Boston University
Kyu-Won Kim
Kyu-Won Kim Seoul National University
Aneesh B. Singhal
Aneesh B. Singhal Massachusetts General Hospital
Anna Devor
Anna Devor Boston University
Igor F. Palacios
Igor F. Palacios Harvard University
Cenk Ayata
Cenk Ayata Harvard University
Karen L. Furie
Karen L. Furie Brown University
Bruce R. Rosen
Bruce R. Rosen Harvard University
Ona Wu
Ona Wu Harvard University

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