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Neuroscience

D-Index
79
Citations
21040
World Ranking
1693
National Ranking
54

Overview

Denis Vivien is affiliated with the Université de Caen Normandie in France, focusing primarily on medical and neuroscientific research. Their work spans multiple fields including Medicine, with 302 publications, and Neuroscience, with 125 publications. Within these fields, Vivien's subfields of study notably include Neurology, Epidemiology, Psychiatry and Mental Health, Molecular Biology, and Cognitive Neuroscience.

The scientist's main research topics encompass diverse areas related to brain health and disease mechanisms. Key topics include Dementia and Cognitive Impairment Research, Acute Ischemic Stroke Management, Neuroinflammation and Neurodegeneration Mechanisms, Traumatic Brain Injury and Neurovascular Disturbances, Alzheimer's disease research and treatments, Protease and Inhibitor Mechanisms, and Functional Brain Connectivity Studies.

Vivien has contributed to numerous publications in several respected venues. Frequent publication outlets include Alzheimer's & Dementia with 27 publications, bioRxiv (Cold Spring Harbor Laboratory) with 13, Scientific Reports with 9, Research Square with 6, and Alzheimer's Research & Therapy with 5 publications.

Some of their recent papers are:

  • White matter hyperintensity topography in Alzheimer's disease and links to cognition, 2021, Alzheimer's & Dementia
  • HGF and MET: From Brain Development to Neurological Disorders, 2021, Frontiers in Cell and Developmental Biology
  • Filling the gaps on stroke research: Focus on inflammation and immunity, 2020, Brain Behavior and Immunity
  • White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition, 2020, Alzheimer's Research & Therapy
  • Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults, 2020, JAMA Neurology

Vivien frequently collaborates with a core group of coauthors. Notable collaborators include Gaël Chételat, Vincent de La Sayette, Julie Gonneaud, Géraldine Poisnel, and Brigitte Landeau. These partnerships suggest a sustained engagement with research teams specializing in neurodegenerative diseases and cognitive disorders.

Best Publications

  • Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

    S Dennler;S Itoh;D Vivien;P ten Dijke

  • The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

    Olivier Nicole;Fabian Docagne;Carine Ali;Isabelle Margaill

  • Stroke and the immune system: from pathophysiology to new therapeutic strategies

    Richard Macrez;Carine Ali;Olivier Toutirais;Brigitte Le Mauff

  • Impaired Glymphatic Perfusion After Strokes Revealed by Contrast-Enhanced MRI A New Target for Fibrinolysis?

    Thomas Gaberel;Clement Gakuba;Romain Goulay;Sara Martinez De Lizarrondo

  • Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain.

    Myriam Bernaudin;Anita Bellail;Hugo H. Marti;Alexandra Yvon

  • Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

    Manuel Yepes;Benoit D Roussel;Carine Ali;Denis Vivien

  • Cytokines in Neuroinflammation and Alzheimers Disease

    Mathias Cacquevel;Nathalie Lebeurrier;Simon Cheenne;Denis Vivien

  • Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain

    Carine Ali;Olivier Nicole;Fabian Docagne;Sylvain Lesne

  • Improving outcome after stroke: overcoming the translational roadblock.

    Matthias Endres;Britta Engelhardt;Jari Koistinaho;Olle Lindvall

  • Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia

    Gemma Llovera;Kerstin Hofmann;Stefan Roth;Angelica Salas-Pérdomo

  • NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production

    Sylvain Lesné;Carine Ali;Cecília Gabriel;Nicole Croci

  • Activation of microglial N‐methyl‐D‐aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain

    Angela M. Kaindl;Vincent Degos;Vincent Degos;Stéphane Peineau;Elodie Gouadon;Elodie Gouadon

  • Neuroprotection Mediated by Glial Cell Line-Derived Neurotrophic Factor: Involvement of a Reduction of NMDA-Induced Calcium Influx by the Mitogen-Activated Protein Kinase Pathway

    Olivier Nicole;Carine Ali;Fabian Docagne;Laurent Plawinski

  • Mouse Model of In Situ Thromboembolic Stroke and Reperfusion

    Cyrille Orset;Richard Macrez;Alan R. Young;Didier Panthou

  • Crosstalk between Rap1 and Rac regulates secretion of sAPPα

    Marjorie Maillet;Sylvain J Robert;Mathias Cacquevel;Monique Gastineau

  • Tissue-Type Plasminogen Activator Crosses the Intact Blood-Brain Barrier by Low-Density Lipoprotein Receptor-Related Protein-Mediated Transcytosis

    Karim Benchenane;Vincent Berezowski;Carine Ali;Mónica Fernández-Monreal

  • A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury.

    Antonio Ruocco;Olivier Nicole;Fabian Docagne;Carine Ali

  • Transforming growth factor-β signalling in brain disorders

    Denis Vivien;Carine Ali

  • General Anesthesia Inhibits the Activity of the "Glymphatic System".

    Clement Gakuba;Thomas Gaberel;Suzanne Goursaud;Jennifer Bourges

  • Transforming Growth Factor-β1 Potentiates Amyloid-β Generation in Astrocytes and in Transgenic Mice

    Sylvain Lesné;Fabian Docagne;Cecı́lia Gabriel;Géraldine Liot

  • Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor β1

    Alain Buisson;Olivier Nicole;Fabian Docagne;Hervé Sartelet

Frequent Co-Authors

Fabian Docagne
Fabian Docagne Université de Caen Normandie
Alain Buisson
Alain Buisson Grenoble Alpes University
Gaël Chételat
Gaël Chételat Université de Caen Normandie
Sylvain Lesné
Sylvain Lesné University of Minnesota
Vincent de la Sayette
Vincent de la Sayette Université de Caen Normandie
Brigitte Landeau
Brigitte Landeau Université de Caen Normandie
Miranka Wirth
Miranka Wirth German Center for Neurodegenerative Diseases
Eider M. Arenaza-Urquijo
Eider M. Arenaza-Urquijo Barcelona Institute for Global Health
Ulrich Dirnagl
Ulrich Dirnagl Charité - University Medicine Berlin
Bruno J. Gonzalez
Bruno J. Gonzalez University of Rouen

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