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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
14748
World Ranking
14241
National Ranking
1005

Overview

Dieter Weichenhan is affiliated with the German Cancer Research Center in Germany. Their research primarily spans the domains of biochemistry, genetics, and molecular biology, with a focus on medicine-related topics. Over their career, they have produced 112 publications in the broader field of Biochemistry, Genetics and Molecular Biology and contributed 54 papers related to Medicine.

Their work delves into various subfields including Molecular Biology, Cancer Research, Hematology, Pulmonary and Respiratory Medicine, and Immunology. This range of expertise supports investigation into complex biological and medical phenomena.

Key topics covered by their research include:

  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Acute Myeloid Leukemia Research
  • Genomics and Chromatin Dynamics
  • Protein Degradation and Inhibitors

Several prominent scientific journals have published their work multiple times, including bioRxiv (Cold Spring Harbor Laboratory) with 17 publications, Nature Communications and Nucleic Acids Research each with 5 publications, Cancer Research with 4, and Blood with 3. This distribution illustrates a consistent engagement with high-impact and specialized outlets in cancer biology and molecular studies.

Their recent notable publications include:

  • "Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin," 2020, Cancer Discovery
  • "Neuronal ensemble-specific DNA methylation strengthens engram stability," 2020, Nature Communications
  • "Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis," 2021, Gut
  • "Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease," 2021, Nature Communications
  • "Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone," 2020, Nature Communications

Throughout their career, Dieter Weichenhan has frequently collaborated with several co-authors including Christoph Plass (64 joint publications), Pavlo Lutsik (31), Joschka Hey (19), Daniel B. Lipka (18), and Matthias Schlesner (13). These collaborations span research efforts in epigenetics and cancer biology.

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis

    Nina Cabezas-Wallscheid;Daniel Klimmeck;Daniel Klimmeck;Jenny Hansson;Daniel B. Lipka

  • Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

    Joachim Weischenfeldt;Ronald Simon;Lars Feuerbach;Karin Schlangen

  • DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

    Christopher C Oakes;Marc Seifert;Yassen Assenov;Lei Gu

  • DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

    David Brocks;Christopher R. Schmidt;Michael Daskalakis;Hyo Sik Jang

  • Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A

    Khelifa Arab;Yoon Jung Park;Anders M. Lindroth;Andrea Schäfer

  • Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

    Christoph Bock;Florian Halbritter;Francisco J. Carmona;Sascha Tierling

  • Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

    Michael Delacher;Charles D. Imbusch;Dieter Weichenhan;Achim Breiling

  • Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products

    Philipp Ehlermann;Kai Eggers;Angelika Bierhaus;Patrick Most

  • Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

    Clarissa Gerhauser;Francesco Favero;Thomas Risch;Ronald Simon

  • Alterations in cardiac DNA methylation in human dilated cardiomyopathy

    Jan Haas;Karen S. Frese;Yoon Jung Park;Yoon Jung Park;Andreas Keller

  • Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

    Patrick Most;Sven T. Pleger;Mirko Völkers;Beatrix Heidt

  • Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

    David Hassel;Tillman Dahme;Jeanette Erdmann;Benjamin Meder

  • Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

    Ralf Gilsbach;Martin Schwaderer;Sebastian Preissl;Björn A. Grüning

  • Targeted Next-Generation Sequencing for the Molecular Genetic Diagnostics of Cardiomyopathies

    Benjamin Meder;Jan Haas;Andreas Keller;Christiane Heid

  • A Modular, Positive Selection Bacterial Artificial Chromosome Vector with Multiple Cloning Sites

    E. Frengen;D. Weichenhan;Baohui Zhao;K. Osoegawa

  • Tagmentation-based whole-genome bisulfite sequencing

    Qi Wang;Lei Gu;Andrew Adey;Bernhard Radlwimmer

  • Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

    Florian Haller;Matthias Bieg;Rainer Will;Cindy Körner

  • Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB

    Angela Garding;Nupur Bhattacharya;Rainer Claus;Rainer Claus;Melanie Ruppel

Frequent Co-Authors

Christoph Plass
Christoph Plass German Cancer Research Center
Roland Eils
Roland Eils Charité - University Medicine Berlin
Hugo A. Katus
Hugo A. Katus Heidelberg University
Benedikt Brors
Benedikt Brors German Cancer Research Center
Matthias Schlesner
Matthias Schlesner University of Augsburg
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Peter Lichter
Peter Lichter German Cancer Research Center
Irina Lehmann
Irina Lehmann Humboldt-Universität zu Berlin
Martin von Bergen
Martin von Bergen Helmholtz Centre for Environmental Research
Karsten Rippe
Karsten Rippe German Cancer Research Center

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