World's Best Scientists 2026 revealed!
Award Badge
Genetics
Germany
2024
Award Badge
Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Genetics

D-Index
110
Citations
55791
World Ranking
532
National Ranking
37

Medicine

D-Index
110
Citations
56494
World Ranking
5465
National Ranking
303

Research.com Recognitions

  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Christoph Plass is affiliated with the German Cancer Research Center in Germany and has contributed extensively to the fields of biochemistry, genetics, and molecular biology as well as medicine. Their research encompasses several subfields, including molecular biology, cancer research, hematology, genetics, and pulmonary and respiratory medicine.

Their work focuses on multiple key topics, such as:

  • Epigenetics and DNA Methylation
  • Acute Myeloid Leukemia Research
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Cancer-related gene regulation
  • Histone Deacetylase Inhibitors Research

Plass has authored and co-authored numerous papers published in prominent scientific journals. Selected recent papers include:

  • Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin, 2020, Cancer Discovery
  • Epigenetic signatures in cancer: proper controls, current challenges and the potential for clinical translation, 2021, Genome Medicine
  • Neuronal ensemble-specific DNA methylation strengthens engram stability, 2020, Nature Communications
  • Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response, 2021, Nature Cancer
  • Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis, 2021, Gut

Their frequent collaborators include Dieter Weichenhan, Pavlo Lutsik, Daniel B. Lipka, Joschka Hey, and Matthias Schlesner.

Plass has published repeatedly in several scientific venues, with a particular number of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Blood
  • International Journal of Cancer
  • HemaSphere

In recognition of their scientific contributions, Plass was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2005.

Best Publications

  • Epigenetic differences arise during the lifetime of monozygotic twins

    Mario F. Fraga;Esteban Ballestar;Maria F. Paz;Santiago Ropero

  • Maftools: efficient and comprehensive analysis of somatic variants in cancer.

    Anand Mayakonda;Anand Mayakonda;De Chen Lin;Yassen Assenov;Yassen Assenov;Christoph Plass;Christoph Plass

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

    Jeremy Schwartzentruber;Andrey Korshunov;Xiao Yang Liu;David T.W. Jones

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

    Joseph F. Costello;Joseph F. Costello;Michael C. Frühwald;Michael C. Frühwald;Dominic J. Smiraglia;Laura J. Rush

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Sebastian Bender;Sebastian Bender;Yujie Tang;Anders M. Lindroth;Volker Hovestadt

  • MGMT testing—the challenges for biomarker-based glioma treatment

    Wolfgang Wick;Michael Weller;Martin van den Bent;Marc Sanson

  • Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis

    Nina Cabezas-Wallscheid;Daniel Klimmeck;Daniel Klimmeck;Jenny Hansson;Daniel B. Lipka

  • Principles for the post-GWAS functional characterization of cancer risk loci

    Matthew L Freedman;Alvaro N A Monteiro;Simon A Gayther;Simon A Gayther;Gerhard A Coetzee

  • BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

    Martje Tönjes;Sebastian Barbus;Yoon Jung Park;Yoon Jung Park;Wei Wang

  • Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

    Christoph Plass;Stefan M. Pfister;Stefan M. Pfister;Anders M. Lindroth;Olga Bogatyrova

  • Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.

    Aparna Raval;Stephan M. Tanner;John C. Byrd;Elizabeth B. Angerman

  • Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

    Sebastian Moran;Anna Martínez-Cardús;Sergi Sayols;Eva Musulén

  • The functional consequences of alternative promoter use in mammalian genomes

    Ramana V. Davuluri;Ramana V. Davuluri;Yutaka Suzuki;Sumio Sugano;Christoph Plass;Christoph Plass

  • Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

    Joachim Weischenfeldt;Ronald Simon;Lars Feuerbach;Karin Schlangen

  • Phase I Study of Decitabine Alone or in Combination With Valproic Acid in Acute Myeloid Leukemia

    William Blum;Rebecca B. Klisovic;Bjoern Hackanson;Zhongfa Liu

  • Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

    Antje Krohn;Tobias Diedler;Lia Burkhardt;Pascale Sophie Mayer

  • Predicting aberrant CpG island methylation.

    F. A. Feltus;E. K. Lee;E. K. Lee;J. F. Costello;Christoph Plass

Frequent Co-Authors

Dieter Weichenhan
Dieter Weichenhan German Cancer Research Center
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Roland Eils
Roland Eils Charité - University Medicine Berlin
Peter Schmezer
Peter Schmezer German Cancer Research Center
Peter Lichter
Peter Lichter German Cancer Research Center
Benedikt Brors
Benedikt Brors German Cancer Research Center
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Joseph F. Costello
Joseph F. Costello University of California, San Francisco
Guido Marcucci
Guido Marcucci City Of Hope National Medical Center
Andreas von Deimling
Andreas von Deimling Heidelberg University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you are interested in studying Genetics in the USA, you may also want to explore related online degrees and career options in the healthcare and life sciences fields. Many students pursue alternative pathways in nursing or healthcare administration, leveraging flexible online programs to broaden their skills.

For those considering nursing, there are nursing schools that dont require teas, making entry into nursing more accessible for many students. Fast-tracked routes, such as online lpn programs, can help you start your healthcare career sooner while still focusing on patient care and clinical skills.

For those aiming for leadership roles, consider the most affordable online mha programs. These degrees offer specialized knowledge in managing healthcare organizations, which is highly valuable alongside scientific backgrounds like genetics.

If you are passionate about teaching, research, or high-level practice, pursuing a phd nursing education online can open doors to advanced positions in academia or healthcare innovation. No matter your interest, online programs provide flexible ways to expand your career options related to genetics.

Best Scientists Citing Christoph Plass

Trending Scientists

Recently Published Articles