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Medicine

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107
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46520
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Research.com Recognitions

  • 2015 - Fellow of the Royal Society of Canada Academy of Science

Overview

Nada Jabado is affiliated with McGill University in Canada. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, particularly in the subfields of Molecular Biology, Genetics, Neurology, Cancer Research, and Immunology.

The main research topics covered by Nada Jabado include:

  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Epigenetics and DNA Methylation
  • Neurofibromatosis and Schwannoma Cases
  • Chromatin Remodeling and Cancer
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer

Several frequent coauthors have contributed to Nada Jabado's publications, including:

  • Claudia L. Kleinman
  • David Jones
  • Sébastien Perreault
  • David S. Ziegler
  • Stefan M. Pfister

Their work has appeared in various publication venues with the highest number of papers in:

  • Neuro-Oncology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Neuro-Oncology Advances

Recent papers authored or coauthored by Nada Jabado include:

  • Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis (2020, Cell)
  • K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas (2022, Nature Genetics)
  • The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial (2023, Nature Medicine)
  • H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2 (2020, Molecular Cell)
  • Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma (2020, Cell)

Nada Jabado was awarded the distinction of Fellow of the Royal Society of Canada in 2015 as part of the Academy of Science.

Best Publications

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

    Jeremy Schwartzentruber;Andrey Korshunov;Xiao Yang Liu;David T.W. Jones

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.

    Dong Anh Khuong-Quang;Pawel Buczkowicz;Patricia Rakopoulos;Xiao Yang Liu

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

    Dominik Sturm;Dominik Sturm;Brent A. Orr;Umut H. Toprak;Volker Hovestadt

  • Dissecting the genomic complexity underlying medulloblastoma

    David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner

  • Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

    Alan Mackay;Anna Burford;Diana Carvalho;Elisa Izquierdo

  • Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

    Tobias Rausch;David T.W. Jones;Marc Zapatka;Adrian M. Stütz

  • Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Sebastian Bender;Sebastian Bender;Yujie Tang;Anders M. Lindroth;Volker Hovestadt

  • Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

    Eric Bouffet;Valérie Larouche;Brittany B. Campbell;Daniele Merico

  • Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

    David T W Jones;Barbara Hutter;Natalie Jäger;Andrey Korshunov;Andrey Korshunov

  • Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

    Marcel Kool;David T.W. Jones;Natalie Jäger;Paul A. Northcott

  • Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

    Ivan Angulo;Oscar Vadas;Fabien Garçon;Edward Banham-Hall

  • Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

    S. C. Mack;H. Witt;R. M. Piro;L. Gu

  • Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

    Dominik Sturm;Sebastian Bender;David T. W. Jones;Peter Lichter

  • Griscelli Disease Maps to Chromosome 15q21 and Is Associated With Mutations in the myosin-Va Gene

    Pastural E;Barrat Fj;Dufourcq-Lagelouse R;Certain S

  • Natural Resistance to Intracellular Infections: Natural Resistance–Associated Macrophage Protein 1 (Nramp1) Functions as a Ph-Dependent Manganese Transporter at the Phagosomal Membrane

    Nada Jabado;Andrzej Jankowski;Samuel Dougaparsad;Virginie Picard

Frequent Co-Authors

Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Andrey Korshunov
Andrey Korshunov German Cancer Research Center
Michael D. Taylor
Michael D. Taylor University of Toronto
David T. W. Jones
David T. W. Jones German Cancer Research Center
Cynthia Hawkins
Cynthia Hawkins University of Toronto
Eric Bouffet
Eric Bouffet University of Toronto
Jacek Majewski
Jacek Majewski McGill University
Uri Tabori
Uri Tabori University of Toronto
Marcel Kool
Marcel Kool German Cancer Research Center
Andreas von Deimling
Andreas von Deimling Heidelberg University

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